Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062113188> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2062113188 endingPage "105" @default.
- W2062113188 startingPage "99" @default.
- W2062113188 abstract "An immunocytochemical technique for simultaneously visualizing two different antigens, dihydroxyphenylalanine (L-DOPA) and dopamine (DA), has been used to investigate the presence of cell bodies containing both compounds L-DOPA and DA and those having only L-DOPA in rat mesencephalon areas. The brain slices were processed with a double peroxidase-antiperoxidase method using simultaneously an incubation of a rabbit anti-L-DOPA serum and a monoclonal anti-DA antibody raised in mouse. Both antigens were revealed by the peroxidase reaction but with different chromogens that are easily distinguishable. In this staining procedure, the first antigen, conjugated DA was stained using the 3,3′-diaminobenzidine (DAB)-Nickel complex; while the second antigen, conjugated L-DOPA, was localized using DAB. The yellow-brown color due to DAB was masked by that of DAB-nickel. The possible existence of both single and double labelings could be worked. We have found many L-DOPA-positive/DA-positive and a few L-DOPA-positive/DA-negative cell bodies in dopaminergic regions in the rat midbrain: substantia nigra, ventral tegmental area, and raphe nuclei. In the locus coeruleus, we noted only L-DOPA-positive/DA-positive cell bodies. These results confirm those previously described for rat and cat hypothalamus, where both immunoreactive-cell body types have been detected: L-DOPA positive/DA positive and L-DOPA positive/DA negative. The existence of neuronal cells containing only L-DOPA is a new neuroanatomic finding, accounting better for the heterogeneity of dopamine systems with respect to physiologic, pharmacologic, and molecular data." @default.
- W2062113188 created "2016-06-24" @default.
- W2062113188 creator A5028906907 @default.
- W2062113188 creator A5063519251 @default.
- W2062113188 creator A5078462648 @default.
- W2062113188 date "1989-01-01" @default.
- W2062113188 modified "2023-09-30" @default.
- W2062113188 title "Identification of L-DOPA-dopamine and L-DOPA cell bodies in the rat mesencephalic dopaminergic cell systems" @default.
- W2062113188 cites W1497427077 @default.
- W2062113188 cites W1964705865 @default.
- W2062113188 cites W1970533599 @default.
- W2062113188 cites W2000062259 @default.
- W2062113188 cites W2013061015 @default.
- W2062113188 cites W2015050779 @default.
- W2062113188 cites W2026381642 @default.
- W2062113188 cites W2028618631 @default.
- W2062113188 cites W2028773214 @default.
- W2062113188 cites W2046327306 @default.
- W2062113188 cites W2052631430 @default.
- W2062113188 cites W2070123502 @default.
- W2062113188 cites W2076832585 @default.
- W2062113188 cites W2088727446 @default.
- W2062113188 cites W2093442042 @default.
- W2062113188 cites W2120601698 @default.
- W2062113188 doi "https://doi.org/10.1002/syn.890040203" @default.
- W2062113188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2781469" @default.
- W2062113188 hasPublicationYear "1989" @default.
- W2062113188 type Work @default.
- W2062113188 sameAs 2062113188 @default.
- W2062113188 citedByCount "26" @default.
- W2062113188 countsByYear W20621131882013 @default.
- W2062113188 countsByYear W20621131882017 @default.
- W2062113188 countsByYear W20621131882018 @default.
- W2062113188 countsByYear W20621131882019 @default.
- W2062113188 countsByYear W20621131882020 @default.
- W2062113188 countsByYear W20621131882021 @default.
- W2062113188 countsByYear W20621131882023 @default.
- W2062113188 crossrefType "journal-article" @default.
- W2062113188 hasAuthorship W2062113188A5028906907 @default.
- W2062113188 hasAuthorship W2062113188A5063519251 @default.
- W2062113188 hasAuthorship W2062113188A5078462648 @default.
- W2062113188 hasConcept C126322002 @default.
- W2062113188 hasConcept C134018914 @default.
- W2062113188 hasConcept C137183658 @default.
- W2062113188 hasConcept C153911025 @default.
- W2062113188 hasConcept C159167319 @default.
- W2062113188 hasConcept C185592680 @default.
- W2062113188 hasConcept C2780938664 @default.
- W2062113188 hasConcept C2780948874 @default.
- W2062113188 hasConcept C3020251336 @default.
- W2062113188 hasConcept C513476851 @default.
- W2062113188 hasConcept C529278444 @default.
- W2062113188 hasConcept C552161191 @default.
- W2062113188 hasConcept C71924100 @default.
- W2062113188 hasConcept C86803240 @default.
- W2062113188 hasConceptScore W2062113188C126322002 @default.
- W2062113188 hasConceptScore W2062113188C134018914 @default.
- W2062113188 hasConceptScore W2062113188C137183658 @default.
- W2062113188 hasConceptScore W2062113188C153911025 @default.
- W2062113188 hasConceptScore W2062113188C159167319 @default.
- W2062113188 hasConceptScore W2062113188C185592680 @default.
- W2062113188 hasConceptScore W2062113188C2780938664 @default.
- W2062113188 hasConceptScore W2062113188C2780948874 @default.
- W2062113188 hasConceptScore W2062113188C3020251336 @default.
- W2062113188 hasConceptScore W2062113188C513476851 @default.
- W2062113188 hasConceptScore W2062113188C529278444 @default.
- W2062113188 hasConceptScore W2062113188C552161191 @default.
- W2062113188 hasConceptScore W2062113188C71924100 @default.
- W2062113188 hasConceptScore W2062113188C86803240 @default.
- W2062113188 hasIssue "2" @default.
- W2062113188 hasLocation W20621131881 @default.
- W2062113188 hasLocation W20621131882 @default.
- W2062113188 hasOpenAccess W2062113188 @default.
- W2062113188 hasPrimaryLocation W20621131881 @default.
- W2062113188 hasRelatedWork W1513336686 @default.
- W2062113188 hasRelatedWork W1981862471 @default.
- W2062113188 hasRelatedWork W2009043849 @default.
- W2062113188 hasRelatedWork W2019923660 @default.
- W2062113188 hasRelatedWork W2032984859 @default.
- W2062113188 hasRelatedWork W2034821677 @default.
- W2062113188 hasRelatedWork W2061909284 @default.
- W2062113188 hasRelatedWork W2066649694 @default.
- W2062113188 hasRelatedWork W2370097487 @default.
- W2062113188 hasRelatedWork W2513128864 @default.
- W2062113188 hasVolume "4" @default.
- W2062113188 isParatext "false" @default.
- W2062113188 isRetracted "false" @default.
- W2062113188 magId "2062113188" @default.
- W2062113188 workType "article" @default.