FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062114042> ?p ?o ?g. }

• W2062114042 endingPage "322" @default.
• W2062114042 startingPage "316" @default.
• W2062114042 abstract "Background: Insulin-like growth factor-II mRNA-binding protein 3 (IMP-3 ), a member of the insulin-like growth factor mRNA-binding protein family, is expressed in several human malignancies, including melanomas. However, the expression of IMP-3 has not been explored in melanoma in situ, various histologic subtypes of invasive melanomas and atypical Spitz tumors. Methods: IMP-3 immunostain was performed in 157 melanocytic lesions. Results: Nearly all benign (8/8), dysplastic (8/8) and Spitz nevi (8/9) were negative for IMP-3. Focal IMP-3 positivity was observed in 5/12 melanoma in situ and 4/15 superficial melanomas (Breslow depth ≤1 mm). Half (10/20) of deep melanomas (Breslow depth >1 mm) and 25/52 metastatic melanomas demonstrated strong IMP-3 staining. IMP-3 expression differs significantly between non-desmoplastic melanomas (superficial and deep) and benign or dysplastic or Spitz nevi (p = 0.0427, respectively). Four of 23 desmoplastic melanomas expressed IMP-3 , which was significantly different from deep melanomas (p = 0.0109). IMP-3 stained 7 of 10 atypical Spitz tumors. The difference between atypical Spitz tumors and Spitz nevi was statistically significant (p = 0.0256). Conclusion: A malignant circumstance, such as non-desmoplastic melanoma or atypical Spitz tumor, can be inferred when IMP-3 is expressed, suggesting potential diagnostic value of IMP-3 in melanocytic lesions. Yu L, Xu H, Wasco MJ, Bourne PA, Ma L. IMP-3 expression in melanocytic lesions." @default.
• W2062114042 created "2016-06-24" @default.
• W2062114042 creator A5008581924 @default.
• W2062114042 creator A5009458650 @default.
• W2062114042 creator A5011954508 @default.
• W2062114042 creator A5032994993 @default.
• W2062114042 creator A5084922819 @default.
• W2062114042 date "2010-03-01" @default.
• W2062114042 modified "2023-09-25" @default.
• W2062114042 title "IMP-3 expression in melanocytic lesions" @default.
• W2062114042 cites W1943557071 @default.
• W2062114042 cites W1964995908 @default.
• W2062114042 cites W1972992454 @default.
• W2062114042 cites W1982581785 @default.
• W2062114042 cites W1988804311 @default.
• W2062114042 cites W1992034858 @default.
• W2062114042 cites W1996910481 @default.
• W2062114042 cites W2000408101 @default.
• W2062114042 cites W2001894998 @default.
• W2062114042 cites W2013626185 @default.
• W2062114042 cites W2031125959 @default.
• W2062114042 cites W2032554396 @default.
• W2062114042 cites W2053613923 @default.
• W2062114042 cites W2065944087 @default.
• W2062114042 cites W2073482890 @default.
• W2062114042 cites W2086959949 @default.
• W2062114042 cites W2089354810 @default.
• W2062114042 cites W2094774666 @default.
• W2062114042 cites W2126051876 @default.
• W2062114042 cites W2164065167 @default.
• W2062114042 cites W4242867261 @default.
• W2062114042 cites W4322700127 @default.
• W2062114042 doi "https://doi.org/10.1111/j.1600-0560.2009.01428.x" @default.
• W2062114042 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19788446" @default.
• W2062114042 hasPublicationYear "2010" @default.
• W2062114042 type Work @default.
• W2062114042 sameAs 2062114042 @default.
• W2062114042 citedByCount "20" @default.
• W2062114042 countsByYear W20621140422012 @default.
• W2062114042 countsByYear W20621140422014 @default.
• W2062114042 countsByYear W20621140422015 @default.
• W2062114042 countsByYear W20621140422016 @default.
• W2062114042 countsByYear W20621140422017 @default.
• W2062114042 countsByYear W20621140422018 @default.
• W2062114042 countsByYear W20621140422020 @default.
• W2062114042 countsByYear W20621140422022 @default.
• W2062114042 crossrefType "journal-article" @default.
• W2062114042 hasAuthorship W2062114042A5008581924 @default.
• W2062114042 hasAuthorship W2062114042A5009458650 @default.
• W2062114042 hasAuthorship W2062114042A5011954508 @default.
• W2062114042 hasAuthorship W2062114042A5032994993 @default.
• W2062114042 hasAuthorship W2062114042A5084922819 @default.
• W2062114042 hasBestOaLocation W20621140422 @default.
• W2062114042 hasConcept C121608353 @default.
• W2062114042 hasConcept C126322002 @default.
• W2062114042 hasConcept C142724271 @default.
• W2062114042 hasConcept C204232928 @default.
• W2062114042 hasConcept C2777411683 @default.
• W2062114042 hasConcept C2777658100 @default.
• W2062114042 hasConcept C2779323059 @default.
• W2062114042 hasConcept C2780212769 @default.
• W2062114042 hasConcept C2908643394 @default.
• W2062114042 hasConcept C4224716 @default.
• W2062114042 hasConcept C502942594 @default.
• W2062114042 hasConcept C530470458 @default.
• W2062114042 hasConcept C71924100 @default.
• W2062114042 hasConceptScore W2062114042C121608353 @default.
• W2062114042 hasConceptScore W2062114042C126322002 @default.
• W2062114042 hasConceptScore W2062114042C142724271 @default.
• W2062114042 hasConceptScore W2062114042C204232928 @default.
• W2062114042 hasConceptScore W2062114042C2777411683 @default.
• W2062114042 hasConceptScore W2062114042C2777658100 @default.
• W2062114042 hasConceptScore W2062114042C2779323059 @default.
• W2062114042 hasConceptScore W2062114042C2780212769 @default.
• W2062114042 hasConceptScore W2062114042C2908643394 @default.
• W2062114042 hasConceptScore W2062114042C4224716 @default.
• W2062114042 hasConceptScore W2062114042C502942594 @default.
• W2062114042 hasConceptScore W2062114042C530470458 @default.
• W2062114042 hasConceptScore W2062114042C71924100 @default.
• W2062114042 hasIssue "3" @default.
• W2062114042 hasLocation W20621140421 @default.
• W2062114042 hasLocation W20621140422 @default.
• W2062114042 hasLocation W20621140423 @default.
• W2062114042 hasOpenAccess W2062114042 @default.
• W2062114042 hasPrimaryLocation W20621140421 @default.
• W2062114042 hasRelatedWork W1988804311 @default.
• W2062114042 hasRelatedWork W2022498945 @default.
• W2062114042 hasRelatedWork W202920663 @default.
• W2062114042 hasRelatedWork W2407881497 @default.
• W2062114042 hasRelatedWork W2413359840 @default.
• W2062114042 hasRelatedWork W2414790453 @default.
• W2062114042 hasRelatedWork W3161434006 @default.
• W2062114042 hasRelatedWork W3163411982 @default.
• W2062114042 hasRelatedWork W4362392281 @default.
• W2062114042 hasRelatedWork W2507619929 @default.
• W2062114042 hasVolume "37" @default.
• W2062114042 isParatext "false" @default.
• W2062114042 isRetracted "false" @default.

• next