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- W2062131150 abstract "Objective: Preclinical studies in gynecologic and other malignancies demonstrate that HDAC inhibitors can impede cancer cell line proliferation in vitro and block the growth of tumors derived from those cell lines in vivo. We used both established ovarian cancer lines and a xenograft model of patient-derived primary serous ovarian tumors to evaluate the efficacy of the HDAC inhibitor panobinostat (LBH589) as a single agent in vitro or in combination with cytotoxic chemotherapy in vivo." @default.
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- W2062131150 date "2011-03-01" @default.
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- W2062131150 title "Influence of the novel histone deacetylase inhibitor panobinostat (LBH589) on the growth of ovarian cancer" @default.
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- W2062131150 doi "https://doi.org/10.1016/j.ygyno.2010.12.170" @default.
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