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- W2062210494 abstract "2,3,6-Tribromo-4,5-dihydroxybenzyl methyl ether (TDB) from the methanolic extract of the red alga Symphyocladia latiuscula exhibits major antioxidant activity. In this study, the activity of TDB against oxidative damage in deoxyribose and DNA was investigated in vitro for potential applications in preventing mutagenesis caused by DNA damage. TDB inhibited the oxidation of deoxyribose at concentrations of up to <TEX>$1{mu}g$</TEX>/mL in the presence of <TEX>$Fe^{+3}$</TEX>-EDTA/<TEX>$H_2O_2$</TEX>. Furthermore, TDB showed no pro oxidant activity as determined by absence of the reduction of bleomycin-<TEX>$Fe^{+3}$</TEX> to bleomycin-<TEX>$Fe^{+2}$</TEX>, which leads to DNA damage. Based on these results, TDB demonstrated considerable antioxidant activity without prooxidant properties." @default.
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- W2062210494 date "2009-06-30" @default.
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- W2062210494 title "Antioxidant Effects of 2,3,6-tribromo-4,5-dihydroxybenzyl Methyl Ether (TDB) from the Red Alga, Symphyocladia latiuscula" @default.
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- W2062210494 doi "https://doi.org/10.5657/fas.2009.12.2.086" @default.
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