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- W2062217050 abstract "To determine if MRI can predict intracerebral plasminogen activation after focal cerebral ischemia (FCI), ischemic regions detected by MRI after 48 h of permanent FCI in rats were compared with areas of increased plasminogen activation, defined by histological zymography after 72 h of ischemia. The overlap between areas of MRI alterations (64.5% +/- 5.4% of total ischemic hemisphere) and areas with increased plasminogen activation (62.2% +/- 3.6%) was significant for the hemisphere (p < 0.001), the cortex (p < 0.05), and the basal ganglia (p < 0.05). Thus, MRI can predict the extent of increased plasminogen activation, which may play a role in BBB-mediated post-ischemic brain edema and secondary hemorrhage." @default.
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- W2062217050 date "2002-11-01" @default.
- W2062217050 modified "2023-09-23" @default.
- W2062217050 title "MRI predicts area of increased plasminogen activation in permanent focal cerebral ischemia" @default.
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- W2062217050 doi "https://doi.org/10.1179/016164102101200799" @default.
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