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- W2062251477 abstract "Modifications in the sensitivity of target-cells to DA or agonists in mouse striatum have been assesses both behaviorally, by scoring a stereotyped behaviour elicited by apomorphine and biochemically, by measurement of HVA and DA levels to evaluate the activity of the feedback loop controlling nigro-striatal neurons. Following the acute administration of α-MPT, hypersensitivity develops in a few hours and decays progressively in 3 days. Since the development of hypersensitivity is prevented by the administration of cycloheximide or anisomycin, two inhibitors of protein synthesis, it is hypothesized that it migth be accounted for by synthesis of new receptor sites." @default.
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- W2062251477 date "1977-08-01" @default.
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- W2062251477 title "Rapid development of hypersensitivity of striatal dopamine receptors induced by alpha-methylparatyrosine and its prevention by protein synthesis inhibitors" @default.
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- W2062251477 doi "https://doi.org/10.1016/0024-3205(77)90510-0" @default.
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