FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062285956> ?p ?o ?g. }

• W2062285956 endingPage "75" @default.
• W2062285956 startingPage "71" @default.
• W2062285956 abstract "According to Traditional Chinese Medicine (TCM) theories, TCM with different meridian tropism have different therapeutic effects. In view of the meridian tropism of Astragalus membranaceus (Huangqi), astragaloside IV, one of the effective phytochemicals of Huangqi, was appointed and observed its distribution in rat tissues following a single intravenous (i.v.) dose. A simple and accurate LC-ESI-MS/MS method was developed and validated for astragaloside IV quantification in heart, liver, spleen, lung and kidney using warfarin as an internal standard (IS). Chromatographic separation was performed on a Eclipse plus C18 (4.6 mm × 100 mm, 1.8 μm) when the flow rate was set at 0.300 mL min−1 and ammonium acetate aqueous solution - acetonitrile was used as mobile phase. The intra- and inter-day precisions of the quality control samples were within 15% and accuracies were within 90.0–110%. The recoveries were more than 90.0% at high, medium and low concentrations, respectively. This method was successfully applied for distribution of astragaloside IV after intravenous (i.v.) dose of 4 mg kg−1 astragaloside IV in rats. Astragaloside IV concentration was highest in liver and kidney and remained much higher than that in other tissues over the experiment course. Lung, heart and spleen were also detected to contain astragaloside IV. The results clearly demonstrated that astragaloside IV was one of the material bases of the meridian tropism of Huangqi." @default.
• W2062285956 created "2016-06-24" @default.
• W2062285956 creator A5006446712 @default.
• W2062285956 creator A5013238240 @default.
• W2062285956 creator A5029636776 @default.
• W2062285956 creator A5042505190 @default.
• W2062285956 creator A5072799173 @default.
• W2062285956 creator A5074964630 @default.
• W2062285956 creator A5075018408 @default.
• W2062285956 creator A5078126271 @default.
• W2062285956 date "2012-12-01" @default.
• W2062285956 modified "2023-10-14" @default.
• W2062285956 title "The experimental study of Astragalus membranaceus on meridian tropsim: The distribution study of astragaloside IV in rat tissues" @default.
• W2062285956 cites W1965791448 @default.
• W2062285956 cites W1973028464 @default.
• W2062285956 cites W1975106483 @default.
• W2062285956 cites W1980644890 @default.
• W2062285956 cites W1985380713 @default.
• W2062285956 cites W1993491132 @default.
• W2062285956 cites W2000410249 @default.
• W2062285956 cites W2019361008 @default.
• W2062285956 cites W2050587933 @default.
• W2062285956 cites W2055412125 @default.
• W2062285956 cites W2057668018 @default.
• W2062285956 cites W2064685888 @default.
• W2062285956 cites W2070416826 @default.
• W2062285956 cites W2079023692 @default.
• W2062285956 cites W2080675167 @default.
• W2062285956 cites W2114277563 @default.
• W2062285956 cites W2115688226 @default.
• W2062285956 cites W2156248278 @default.
• W2062285956 doi "https://doi.org/10.1016/j.jchromb.2012.10.024" @default.
• W2062285956 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23217309" @default.
• W2062285956 hasPublicationYear "2012" @default.
• W2062285956 type Work @default.
• W2062285956 sameAs 2062285956 @default.
• W2062285956 citedByCount "29" @default.
• W2062285956 countsByYear W20622859562013 @default.
• W2062285956 countsByYear W20622859562014 @default.
• W2062285956 countsByYear W20622859562015 @default.
• W2062285956 countsByYear W20622859562016 @default.
• W2062285956 countsByYear W20622859562017 @default.
• W2062285956 countsByYear W20622859562018 @default.
• W2062285956 countsByYear W20622859562020 @default.
• W2062285956 countsByYear W20622859562021 @default.
• W2062285956 countsByYear W20622859562022 @default.
• W2062285956 countsByYear W20622859562023 @default.
• W2062285956 crossrefType "journal-article" @default.
• W2062285956 hasAuthorship W2062285956A5006446712 @default.
• W2062285956 hasAuthorship W2062285956A5013238240 @default.
• W2062285956 hasAuthorship W2062285956A5029636776 @default.
• W2062285956 hasAuthorship W2062285956A5042505190 @default.
• W2062285956 hasAuthorship W2062285956A5072799173 @default.
• W2062285956 hasAuthorship W2062285956A5074964630 @default.
• W2062285956 hasAuthorship W2062285956A5075018408 @default.
• W2062285956 hasAuthorship W2062285956A5078126271 @default.
• W2062285956 hasConcept C121332964 @default.
• W2062285956 hasConcept C126322002 @default.
• W2062285956 hasConcept C1276947 @default.
• W2062285956 hasConcept C142724271 @default.
• W2062285956 hasConcept C179691212 @default.
• W2062285956 hasConcept C179998833 @default.
• W2062285956 hasConcept C185592680 @default.
• W2062285956 hasConcept C188947578 @default.
• W2062285956 hasConcept C204787440 @default.
• W2062285956 hasConcept C2777061170 @default.
• W2062285956 hasConcept C2780091579 @default.
• W2062285956 hasConcept C2780798337 @default.
• W2062285956 hasConcept C43617362 @default.
• W2062285956 hasConcept C71924100 @default.
• W2062285956 hasConceptScore W2062285956C121332964 @default.
• W2062285956 hasConceptScore W2062285956C126322002 @default.
• W2062285956 hasConceptScore W2062285956C1276947 @default.
• W2062285956 hasConceptScore W2062285956C142724271 @default.
• W2062285956 hasConceptScore W2062285956C179691212 @default.
• W2062285956 hasConceptScore W2062285956C179998833 @default.
• W2062285956 hasConceptScore W2062285956C185592680 @default.
• W2062285956 hasConceptScore W2062285956C188947578 @default.
• W2062285956 hasConceptScore W2062285956C204787440 @default.
• W2062285956 hasConceptScore W2062285956C2777061170 @default.
• W2062285956 hasConceptScore W2062285956C2780091579 @default.
• W2062285956 hasConceptScore W2062285956C2780798337 @default.
• W2062285956 hasConceptScore W2062285956C43617362 @default.
• W2062285956 hasConceptScore W2062285956C71924100 @default.
• W2062285956 hasFunder F4320317321 @default.
• W2062285956 hasFunder F4320321001 @default.
• W2062285956 hasFunder F4320321106 @default.
• W2062285956 hasLocation W20622859561 @default.
• W2062285956 hasLocation W20622859562 @default.
• W2062285956 hasOpenAccess W2062285956 @default.
• W2062285956 hasPrimaryLocation W20622859561 @default.
• W2062285956 hasRelatedWork W2072506126 @default.
• W2062285956 hasRelatedWork W2099783185 @default.
• W2062285956 hasRelatedWork W2347522703 @default.
• W2062285956 hasRelatedWork W2360855610 @default.
• W2062285956 hasRelatedWork W2366779683 @default.
• W2062285956 hasRelatedWork W2372513339 @default.
• W2062285956 hasRelatedWork W2373658683 @default.

• next