FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062289201> ?p ?o ?g. }

• W2062289201 endingPage "221" @default.
• W2062289201 startingPage "217" @default.
• W2062289201 abstract "Objective: To evaluate the clinical usefulness of serum autoantibody profiling in patients with autoimmune myositis.Methods: We retrospectively studied 74 consecutive patients: 68 had definite or probable myositis according to Bohan–Peter criteria, six suffered from antisynthetase syndrome with subclinical myopathy. Myositis specific antibodies (MSA) (anti-ARS, -SRP, -Mi-2) were determined by RNA immunoprecipitation or immunoblot, myositis associated antibodies (MAA) (anti-RoRNP, -U1RNP, -PM/Scl, -Ku) by immunoblot.Results: Forty-three patients (58%) were positive for MSA: anti-Jo-1 in 15/27 polymyositis (PM) (55%), 4/33 dermatomyositis (DM) (12%), 1/8 overlap (12%) and 2/6 antisynthetase syndrome (33%); anti-ARS non-Jo-1 in 1/27 PM (4%), 2/33 DM (6%) and 4/6 antisynthetase syndrome (67%); anti-Mi-2 in 1/27 PM (4%) and 11/33 DM (33%); anti-SRP in 3/27 PM (11%) and 1/33 DM (3%). One patient was anti-Jo-1/Mi-2 positive, one anti-Jo-1/SRP positive. Moreover, 27 patients (36%) were positive for MAA: anti-Ro/SSA in 8/27 PM (30%), 7/33 DM (21%), 1/8 overlap (12%), and 3/6 antisynthetase syndrome (50%); anti-U1RNP in 1/27 PM (3.7%), 1/33 DM (3%), and 2/8 overlap (25%); anti-PM/Scl in 2/8 overlap (25%), anti-Ku in 2/8 overlap (25%). Anti-Jo-1 was predominantly associated with PM, anti-Mi-2 was almost exclusively found in DM patients. Anti-ARS antibodies were closely associated with interstitial lung disease and polyarthritis; notably, anti-ARS non-Jo-1 was more frequent in patients without overt muscle alterations. Anti-Ro/SSA antibody was not associated with any disease subset, but significantly more frequent in antisynthetase syndrome.Conclusions: Searching for MSA and MAA in patients with autoimmmune myositis is recommended because of its diagnostic and clinical value. Anti-ARS non-Jo-1 antibodies seem to preferentially target patients with pulmonary fibrosis without overt myopathy." @default.
• W2062289201 created "2016-06-24" @default.
• W2062289201 creator A5006589173 @default.
• W2062289201 creator A5015954010 @default.
• W2062289201 creator A5023500837 @default.
• W2062289201 creator A5031900368 @default.
• W2062289201 creator A5038006814 @default.
• W2062289201 creator A5038036832 @default.
• W2062289201 creator A5051145762 @default.
• W2062289201 creator A5069825343 @default.
• W2062289201 creator A5074477451 @default.
• W2062289201 creator A5080993054 @default.
• W2062289201 date "2006-01-01" @default.
• W2062289201 modified "2023-10-17" @default.
• W2062289201 title "Clinical implications of autoantibody screening in patients with autoimmune myositis" @default.
• W2062289201 cites W132981314 @default.
• W2062289201 cites W1971734001 @default.
• W2062289201 cites W1974440177 @default.
• W2062289201 cites W1980510932 @default.
• W2062289201 cites W1985287023 @default.
• W2062289201 cites W1985918110 @default.
• W2062289201 cites W1987353768 @default.
• W2062289201 cites W1990793218 @default.
• W2062289201 cites W1996842986 @default.
• W2062289201 cites W1997602533 @default.
• W2062289201 cites W2008750539 @default.
• W2062289201 cites W2014321075 @default.
• W2062289201 cites W2014929518 @default.
• W2062289201 cites W2017455399 @default.
• W2062289201 cites W2017862162 @default.
• W2062289201 cites W2018083990 @default.
• W2062289201 cites W2049484723 @default.
• W2062289201 cites W2052319992 @default.
• W2062289201 cites W2057134454 @default.
• W2062289201 cites W2069359556 @default.
• W2062289201 cites W2071793391 @default.
• W2062289201 cites W2072335655 @default.
• W2062289201 cites W2080813348 @default.
• W2062289201 cites W2104077617 @default.
• W2062289201 cites W2119335684 @default.
• W2062289201 cites W2165911231 @default.
• W2062289201 cites W2170200935 @default.
• W2062289201 cites W2314311014 @default.
• W2062289201 cites W2317272504 @default.
• W2062289201 cites W4211050134 @default.
• W2062289201 cites W4237668060 @default.
• W2062289201 cites W3022664073 @default.
• W2062289201 doi "https://doi.org/10.1080/08916930600622645" @default.
• W2062289201 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16769655" @default.
• W2062289201 hasPublicationYear "2006" @default.
• W2062289201 type Work @default.
• W2062289201 sameAs 2062289201 @default.
• W2062289201 citedByCount "85" @default.
• W2062289201 countsByYear W20622892012012 @default.
• W2062289201 countsByYear W20622892012013 @default.
• W2062289201 countsByYear W20622892012014 @default.
• W2062289201 countsByYear W20622892012015 @default.
• W2062289201 countsByYear W20622892012016 @default.
• W2062289201 countsByYear W20622892012017 @default.
• W2062289201 countsByYear W20622892012018 @default.
• W2062289201 countsByYear W20622892012019 @default.
• W2062289201 countsByYear W20622892012020 @default.
• W2062289201 countsByYear W20622892012021 @default.
• W2062289201 countsByYear W20622892012022 @default.
• W2062289201 countsByYear W20622892012023 @default.
• W2062289201 crossrefType "journal-article" @default.
• W2062289201 hasAuthorship W2062289201A5006589173 @default.
• W2062289201 hasAuthorship W2062289201A5015954010 @default.
• W2062289201 hasAuthorship W2062289201A5023500837 @default.
• W2062289201 hasAuthorship W2062289201A5031900368 @default.
• W2062289201 hasAuthorship W2062289201A5038006814 @default.
• W2062289201 hasAuthorship W2062289201A5038036832 @default.
• W2062289201 hasAuthorship W2062289201A5051145762 @default.
• W2062289201 hasAuthorship W2062289201A5069825343 @default.
• W2062289201 hasAuthorship W2062289201A5074477451 @default.
• W2062289201 hasAuthorship W2062289201A5080993054 @default.
• W2062289201 hasConcept C113280763 @default.
• W2062289201 hasConcept C126322002 @default.
• W2062289201 hasConcept C142724271 @default.
• W2062289201 hasConcept C159654299 @default.
• W2062289201 hasConcept C163764329 @default.
• W2062289201 hasConcept C203014093 @default.
• W2062289201 hasConcept C2775941666 @default.
• W2062289201 hasConcept C2777077863 @default.
• W2062289201 hasConcept C2777543607 @default.
• W2062289201 hasConcept C2777714996 @default.
• W2062289201 hasConcept C2778751314 @default.
• W2062289201 hasConcept C2778917330 @default.
• W2062289201 hasConcept C2779017958 @default.
• W2062289201 hasConcept C2779134260 @default.
• W2062289201 hasConcept C2779387793 @default.
• W2062289201 hasConcept C2781232998 @default.
• W2062289201 hasConcept C71924100 @default.
• W2062289201 hasConcept C90924648 @default.
• W2062289201 hasConceptScore W2062289201C113280763 @default.
• W2062289201 hasConceptScore W2062289201C126322002 @default.
• W2062289201 hasConceptScore W2062289201C142724271 @default.
• W2062289201 hasConceptScore W2062289201C159654299 @default.

• next