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- W2062297235 abstract "We previously showed that modified A/Puerto Rico/8/34 (PR8) influenza master strain had improved viral rescue and growth properties in African green monkey kidney (Vero) cell line by introducing NS gene of Vero-adapted A/England/1/53 (vaEng53). In the present study, it was found that the NS1 protein derived from vaEng53 was extensively accumulated in the nuclei than that of PR8. This accumulation was caused by 7 amino acid differences in C-terminal region of NS1 protein. These results suggest that specific accumulation of NS1 protein may contribute to efficient viral replication in Vero cells." @default.
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- W2062297235 date "2007-05-01" @default.
- W2062297235 modified "2023-09-27" @default.
- W2062297235 title "Extensive Accumulation of Influenza Virus NS1 Protein in the Nuclei Causes Effective Viral Growth in Vero Cells" @default.
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- W2062297235 doi "https://doi.org/10.1111/j.1348-0421.2007.tb03935.x" @default.
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