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• W2062334191 abstract "HER2-targeted therapies have revolutionized the outcome of patients with HER2-positive breast cancer. Pertuzumab is the first in a new class of monoclonal antibodies that target the extracellular dimerization domain of HER2 receptors, also known as HER dimerization inhibitors. The development of pertuzumab and preclinical and clinical data in breast cancer are reviewed. Regulatory affairs related to pertuzumab and the recent accelerated approval granted by the FDA for the treatment of breast cancer in the neoadjuvant setting are also covered. This process opens doors for further approvals which could considerably shorten the time between initial drug development and availability." @default.
• W2062334191 created "2016-06-24" @default.
• W2062334191 creator A5003348942 @default.
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• W2062334191 date "2014-06-12" @default.
• W2062334191 modified "2023-10-17" @default.
• W2062334191 title "Pertuzumab for the Treatment of Breast Cancer" @default.
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• W2062334191 doi "https://doi.org/10.3109/07357907.2014.922570" @default.
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