FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062369968> ?p ?o ?g. }

• W2062369968 endingPage "1961" @default.
• W2062369968 startingPage "1957" @default.
• W2062369968 abstract "An increase in the severity of schizophrenia through consecutive generations (anticipation) has been found in some studies of families with affected members. Anticipation in five neurologlcai disorders is known to arise from the expansion of CAG repeats between generations of affected individuais. The ‘repeat expansion detection’ method was used to screen indlviduai genomes for the size of such expansions in a sampie of schizophrenic and normai sub jects. Comparison of the frequency distribution of CAG expansions observed in schizophrenic patients to that for normal subjects, showed that there are significantly more expansions in patients (p = 0.048). When male and female subjects are considered separateiy, there is a highly significant difference in the distribution of repeat sizes found between affected and normal females (p = 0.0023) but no significant difference between affected and normal males. Over all there is a 28% excess of expansions observed in affected versus normal females, and their presence confers a relative risk of 4.12 (p <0.005). in contrast, the frequency distribution of age-at-onset with respect to repeat size is nearly the same in male and female patients and, when the sexes are combined, the larger (CAG)69–136 expansions are associated with a younger age-at-onset (p = 0.02)." @default.
• W2062369968 created "2016-06-24" @default.
• W2062369968 creator A5016651371 @default.
• W2062369968 creator A5025642426 @default.
• W2062369968 creator A5030220819 @default.
• W2062369968 creator A5074274548 @default.
• W2062369968 creator A5090482548 @default.
• W2062369968 date "1995-01-01" @default.
• W2062369968 modified "2023-10-18" @default.
• W2062369968 title "CAG repeat expansions and schizophrenia: association with disease in females and with early age-at-onset" @default.
• W2062369968 cites W1491248060 @default.
• W2062369968 cites W1561216395 @default.
• W2062369968 cites W1966489527 @default.
• W2062369968 cites W1970972148 @default.
• W2062369968 cites W1973055895 @default.
• W2062369968 cites W1981578816 @default.
• W2062369968 cites W2002664886 @default.
• W2062369968 cites W2012481532 @default.
• W2062369968 cites W2019650070 @default.
• W2062369968 cites W2020227900 @default.
• W2062369968 cites W2025497083 @default.
• W2062369968 cites W2044559546 @default.
• W2062369968 cites W2051740298 @default.
• W2062369968 cites W2052961349 @default.
• W2062369968 cites W2053714596 @default.
• W2062369968 cites W2054869090 @default.
• W2062369968 cites W2058803495 @default.
• W2062369968 cites W2073012734 @default.
• W2062369968 cites W2090476855 @default.
• W2062369968 cites W2113333419 @default.
• W2062369968 cites W2121642311 @default.
• W2062369968 cites W2123179257 @default.
• W2062369968 cites W2149355456 @default.
• W2062369968 cites W2155225654 @default.
• W2062369968 cites W2168338263 @default.
• W2062369968 cites W2179102879 @default.
• W2062369968 cites W2255469197 @default.
• W2062369968 cites W2600639051 @default.
• W2062369968 cites W2764362690 @default.
• W2062369968 doi "https://doi.org/10.1093/hmg/4.10.1957" @default.
• W2062369968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8595421" @default.
• W2062369968 hasPublicationYear "1995" @default.
• W2062369968 type Work @default.
• W2062369968 sameAs 2062369968 @default.
• W2062369968 citedByCount "110" @default.
• W2062369968 countsByYear W20623699682016 @default.
• W2062369968 crossrefType "journal-article" @default.
• W2062369968 hasAuthorship W2062369968A5016651371 @default.
• W2062369968 hasAuthorship W2062369968A5025642426 @default.
• W2062369968 hasAuthorship W2062369968A5030220819 @default.
• W2062369968 hasAuthorship W2062369968A5074274548 @default.
• W2062369968 hasAuthorship W2062369968A5090482548 @default.
• W2062369968 hasConcept C104317684 @default.
• W2062369968 hasConcept C118552586 @default.
• W2062369968 hasConcept C126322002 @default.
• W2062369968 hasConcept C134018914 @default.
• W2062369968 hasConcept C144024400 @default.
• W2062369968 hasConcept C149923435 @default.
• W2062369968 hasConcept C154945302 @default.
• W2062369968 hasConcept C15744967 @default.
• W2062369968 hasConcept C166252455 @default.
• W2062369968 hasConcept C176777502 @default.
• W2062369968 hasConcept C180754005 @default.
• W2062369968 hasConcept C2776412080 @default.
• W2062369968 hasConcept C2777767895 @default.
• W2062369968 hasConcept C2779134260 @default.
• W2062369968 hasConcept C2779727114 @default.
• W2062369968 hasConcept C41008148 @default.
• W2062369968 hasConcept C42407357 @default.
• W2062369968 hasConcept C54355233 @default.
• W2062369968 hasConcept C71924100 @default.
• W2062369968 hasConcept C86803240 @default.
• W2062369968 hasConceptScore W2062369968C104317684 @default.
• W2062369968 hasConceptScore W2062369968C118552586 @default.
• W2062369968 hasConceptScore W2062369968C126322002 @default.
• W2062369968 hasConceptScore W2062369968C134018914 @default.
• W2062369968 hasConceptScore W2062369968C144024400 @default.
• W2062369968 hasConceptScore W2062369968C149923435 @default.
• W2062369968 hasConceptScore W2062369968C154945302 @default.
• W2062369968 hasConceptScore W2062369968C15744967 @default.
• W2062369968 hasConceptScore W2062369968C166252455 @default.
• W2062369968 hasConceptScore W2062369968C176777502 @default.
• W2062369968 hasConceptScore W2062369968C180754005 @default.
• W2062369968 hasConceptScore W2062369968C2776412080 @default.
• W2062369968 hasConceptScore W2062369968C2777767895 @default.
• W2062369968 hasConceptScore W2062369968C2779134260 @default.
• W2062369968 hasConceptScore W2062369968C2779727114 @default.
• W2062369968 hasConceptScore W2062369968C41008148 @default.
• W2062369968 hasConceptScore W2062369968C42407357 @default.
• W2062369968 hasConceptScore W2062369968C54355233 @default.
• W2062369968 hasConceptScore W2062369968C71924100 @default.
• W2062369968 hasConceptScore W2062369968C86803240 @default.
• W2062369968 hasIssue "10" @default.
• W2062369968 hasLocation W20623699681 @default.
• W2062369968 hasLocation W20623699682 @default.
• W2062369968 hasOpenAccess W2062369968 @default.
• W2062369968 hasPrimaryLocation W20623699681 @default.
• W2062369968 hasRelatedWork W1491248060 @default.

• next