FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062384018> ?p ?o ?g. }

• W2062384018 endingPage "781" @default.
• W2062384018 startingPage "776" @default.
• W2062384018 abstract "Abstract Background The ACRP30/adiponectin gene on chromosome 3q27, a region linked to the metabolic syndrome, encodes for the abundant adipocyte‐specific secreted protein. Consistent rodent and human studies suggested that this adipokine may be a molecular link between metabolic and cardiovascular diseases. Aims In order to investigate the role of single nucleotide polymorphisms (SNPs) within the APM1 gene in the susceptibility to coronary artery disease (CAD), we performed a case‐control study on Caucasian Type 2 (non‐insulin‐dependent) diabetic patients, a population at high‐risk for CAD. Methods Five APM1 SNPs were genotyped in 162 Type 2 diabetic French and Swiss subjects with CAD and in 315 Type 2 diabetic French and Swiss subjects without CAD. Results In univariate analysis, SNP+45 T>G was associated with CAD (OR 1.9 95% CI 1.2–2.9 P = 0.0036). In multivariate analysis, SNP+45 T>G remained associated with CAD (OR 1.2 95% CI 0.8–1.9 P = 0.017), independently of classical cardiovascular risk factors including components of the metabolic syndrome. SNP haplotype analyses revealed a CAD protective combination of all SNP wild‐type alleles (OR 0.5 95% CI 0.3–0.7 P = 0.0006). Conclusions Our study, performed in diabetic subjects, revealed an association between individual SNP+45 in the APM1 gene and CAD. Furthermore, the susceptibility for CAD due to SNP+45 was independent of classic cardiovascular risk factors. Further studies will be necessary to confirm the role of SNP+45 in the development of CAD. However, ACRP30/adiponectin may contribute to atherosclerosis susceptibility in high‐risk populations such as Type 2 diabetic subjects." @default.
• W2062384018 created "2016-06-24" @default.
• W2062384018 creator A5015465194 @default.
• W2062384018 creator A5035511168 @default.
• W2062384018 creator A5047197856 @default.
• W2062384018 creator A5051582802 @default.
• W2062384018 creator A5055112262 @default.
• W2062384018 creator A5072036478 @default.
• W2062384018 date "2004-06-21" @default.
• W2062384018 modified "2023-10-15" @default.
• W2062384018 title "The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non-insulin-dependent) diabetes mellitus" @default.
• W2062384018 cites W1587875569 @default.
• W2062384018 cites W1592191138 @default.
• W2062384018 cites W1981261500 @default.
• W2062384018 cites W2001727439 @default.
• W2062384018 cites W2063318299 @default.
• W2062384018 cites W2069497802 @default.
• W2062384018 cites W2072262664 @default.
• W2062384018 cites W2088622017 @default.
• W2062384018 cites W2096773810 @default.
• W2062384018 cites W2097060572 @default.
• W2062384018 cites W2097504226 @default.
• W2062384018 cites W2102422654 @default.
• W2062384018 cites W2106550052 @default.
• W2062384018 cites W2108931588 @default.
• W2062384018 cites W2120462461 @default.
• W2062384018 cites W2130670158 @default.
• W2062384018 cites W2132681327 @default.
• W2062384018 cites W2139801418 @default.
• W2062384018 cites W2143497221 @default.
• W2062384018 cites W2147921895 @default.
• W2062384018 cites W2156260257 @default.
• W2062384018 cites W2159829835 @default.
• W2062384018 cites W2160589226 @default.
• W2062384018 cites W2166370133 @default.
• W2062384018 doi "https://doi.org/10.1111/j.1464-5491.2004.01224.x" @default.
• W2062384018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15209773" @default.
• W2062384018 hasPublicationYear "2004" @default.
• W2062384018 type Work @default.
• W2062384018 sameAs 2062384018 @default.
• W2062384018 citedByCount "95" @default.
• W2062384018 countsByYear W20623840182012 @default.
• W2062384018 countsByYear W20623840182013 @default.
• W2062384018 countsByYear W20623840182014 @default.
• W2062384018 countsByYear W20623840182016 @default.
• W2062384018 countsByYear W20623840182017 @default.
• W2062384018 countsByYear W20623840182018 @default.
• W2062384018 countsByYear W20623840182019 @default.
• W2062384018 countsByYear W20623840182022 @default.
• W2062384018 crossrefType "journal-article" @default.
• W2062384018 hasAuthorship W2062384018A5015465194 @default.
• W2062384018 hasAuthorship W2062384018A5035511168 @default.
• W2062384018 hasAuthorship W2062384018A5047197856 @default.
• W2062384018 hasAuthorship W2062384018A5051582802 @default.
• W2062384018 hasAuthorship W2062384018A5055112262 @default.
• W2062384018 hasAuthorship W2062384018A5072036478 @default.
• W2062384018 hasConcept C104317684 @default.
• W2062384018 hasConcept C126322002 @default.
• W2062384018 hasConcept C134018914 @default.
• W2062384018 hasConcept C135763542 @default.
• W2062384018 hasConcept C139275648 @default.
• W2062384018 hasConcept C153209595 @default.
• W2062384018 hasConcept C180754005 @default.
• W2062384018 hasConcept C194832188 @default.
• W2062384018 hasConcept C197754878 @default.
• W2062384018 hasConcept C2776782570 @default.
• W2062384018 hasConcept C2777180221 @default.
• W2062384018 hasConcept C2777391703 @default.
• W2062384018 hasConcept C2778213512 @default.
• W2062384018 hasConcept C2779306644 @default.
• W2062384018 hasConcept C2780578515 @default.
• W2062384018 hasConcept C2908647359 @default.
• W2062384018 hasConcept C2910068830 @default.
• W2062384018 hasConcept C54355233 @default.
• W2062384018 hasConcept C555293320 @default.
• W2062384018 hasConcept C60644358 @default.
• W2062384018 hasConcept C71924100 @default.
• W2062384018 hasConcept C86803240 @default.
• W2062384018 hasConcept C99454951 @default.
• W2062384018 hasConceptScore W2062384018C104317684 @default.
• W2062384018 hasConceptScore W2062384018C126322002 @default.
• W2062384018 hasConceptScore W2062384018C134018914 @default.
• W2062384018 hasConceptScore W2062384018C135763542 @default.
• W2062384018 hasConceptScore W2062384018C139275648 @default.
• W2062384018 hasConceptScore W2062384018C153209595 @default.
• W2062384018 hasConceptScore W2062384018C180754005 @default.
• W2062384018 hasConceptScore W2062384018C194832188 @default.
• W2062384018 hasConceptScore W2062384018C197754878 @default.
• W2062384018 hasConceptScore W2062384018C2776782570 @default.
• W2062384018 hasConceptScore W2062384018C2777180221 @default.
• W2062384018 hasConceptScore W2062384018C2777391703 @default.
• W2062384018 hasConceptScore W2062384018C2778213512 @default.
• W2062384018 hasConceptScore W2062384018C2779306644 @default.
• W2062384018 hasConceptScore W2062384018C2780578515 @default.
• W2062384018 hasConceptScore W2062384018C2908647359 @default.
• W2062384018 hasConceptScore W2062384018C2910068830 @default.
• W2062384018 hasConceptScore W2062384018C54355233 @default.
• W2062384018 hasConceptScore W2062384018C555293320 @default.

• next