Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062400487> ?p ?o ?g. }
- W2062400487 endingPage "299" @default.
- W2062400487 startingPage "288" @default.
- W2062400487 abstract "Background: A number of different molecules are known to be involved in the signal pathway to release histamine from mast cells, among which arachidonic acid (AA) is one of the key mediators. On the other hand, we found that the application of compound 48/80, a typical histamine liberator, generated superoxide in mast cells. In the present study, we investigated the mechanism of superoxide production in mast cells with respect to AA signaling in conjunction with a fine structural analysis. Methods: Superoxide production was monitored by chemiluminescence in rat peritoneal mast cells and their subfractions after various treatments. For scanning electron micrography, the conditions for fixation and freeze-fracture were optimized to get natural fine images. Results: Compound 48/80 induced superoxide production in the isolated mast cells and some of their subfractions possibly through intracellular increase in Ca2+ concentration, activation of cytosolic phospholipase A2, and release of AA. Discussion: The present results indicate the critical role of AA in the signal pathway to generate superoxide from mast cells in response to compound 48/80." @default.
- W2062400487 created "2016-06-24" @default.
- W2062400487 creator A5006653971 @default.
- W2062400487 creator A5021973822 @default.
- W2062400487 creator A5032971154 @default.
- W2062400487 creator A5054018959 @default.
- W2062400487 creator A5057882737 @default.
- W2062400487 creator A5067360623 @default.
- W2062400487 creator A5070302842 @default.
- W2062400487 date "2003-01-01" @default.
- W2062400487 modified "2023-10-14" @default.
- W2062400487 title "Involvement of Arachidonic Acid in Nonimmunologic Production of Superoxide in Mast Cells" @default.
- W2062400487 cites W1492252673 @default.
- W2062400487 cites W1516582678 @default.
- W2062400487 cites W1525360648 @default.
- W2062400487 cites W1570720342 @default.
- W2062400487 cites W1581684345 @default.
- W2062400487 cites W1585823649 @default.
- W2062400487 cites W1604764621 @default.
- W2062400487 cites W1664326306 @default.
- W2062400487 cites W183609828 @default.
- W2062400487 cites W1975002369 @default.
- W2062400487 cites W1979421598 @default.
- W2062400487 cites W1988251596 @default.
- W2062400487 cites W2008243630 @default.
- W2062400487 cites W2017668832 @default.
- W2062400487 cites W2026358430 @default.
- W2062400487 cites W2041622964 @default.
- W2062400487 cites W2049131840 @default.
- W2062400487 cites W2062701938 @default.
- W2062400487 cites W2064655962 @default.
- W2062400487 cites W2068299368 @default.
- W2062400487 cites W2072608243 @default.
- W2062400487 cites W2077904086 @default.
- W2062400487 cites W2089311757 @default.
- W2062400487 cites W2090711023 @default.
- W2062400487 cites W2114482761 @default.
- W2062400487 cites W2114773848 @default.
- W2062400487 cites W2117966002 @default.
- W2062400487 cites W2128125228 @default.
- W2062400487 cites W2137552764 @default.
- W2062400487 cites W2153539273 @default.
- W2062400487 cites W2156060851 @default.
- W2062400487 cites W2156166697 @default.
- W2062400487 cites W2222229959 @default.
- W2062400487 cites W2399591470 @default.
- W2062400487 cites W2402874995 @default.
- W2062400487 cites W2404400511 @default.
- W2062400487 cites W2410566333 @default.
- W2062400487 cites W2433767276 @default.
- W2062400487 cites W618630104 @default.
- W2062400487 doi "https://doi.org/10.1159/000070216" @default.
- W2062400487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12740530" @default.
- W2062400487 hasPublicationYear "2003" @default.
- W2062400487 type Work @default.
- W2062400487 sameAs 2062400487 @default.
- W2062400487 citedByCount "3" @default.
- W2062400487 countsByYear W20624004872014 @default.
- W2062400487 countsByYear W20624004872021 @default.
- W2062400487 crossrefType "journal-article" @default.
- W2062400487 hasAuthorship W2062400487A5006653971 @default.
- W2062400487 hasAuthorship W2062400487A5021973822 @default.
- W2062400487 hasAuthorship W2062400487A5032971154 @default.
- W2062400487 hasAuthorship W2062400487A5054018959 @default.
- W2062400487 hasAuthorship W2062400487A5057882737 @default.
- W2062400487 hasAuthorship W2062400487A5067360623 @default.
- W2062400487 hasAuthorship W2062400487A5070302842 @default.
- W2062400487 hasConcept C1122143 @default.
- W2062400487 hasConcept C170493617 @default.
- W2062400487 hasConcept C181199279 @default.
- W2062400487 hasConcept C185592680 @default.
- W2062400487 hasConcept C203014093 @default.
- W2062400487 hasConcept C2776551241 @default.
- W2062400487 hasConcept C2778078955 @default.
- W2062400487 hasConcept C2779726688 @default.
- W2062400487 hasConcept C2780795997 @default.
- W2062400487 hasConcept C2781082844 @default.
- W2062400487 hasConcept C49802076 @default.
- W2062400487 hasConcept C55493867 @default.
- W2062400487 hasConcept C86803240 @default.
- W2062400487 hasConcept C95444343 @default.
- W2062400487 hasConcept C98274493 @default.
- W2062400487 hasConceptScore W2062400487C1122143 @default.
- W2062400487 hasConceptScore W2062400487C170493617 @default.
- W2062400487 hasConceptScore W2062400487C181199279 @default.
- W2062400487 hasConceptScore W2062400487C185592680 @default.
- W2062400487 hasConceptScore W2062400487C203014093 @default.
- W2062400487 hasConceptScore W2062400487C2776551241 @default.
- W2062400487 hasConceptScore W2062400487C2778078955 @default.
- W2062400487 hasConceptScore W2062400487C2779726688 @default.
- W2062400487 hasConceptScore W2062400487C2780795997 @default.
- W2062400487 hasConceptScore W2062400487C2781082844 @default.
- W2062400487 hasConceptScore W2062400487C49802076 @default.
- W2062400487 hasConceptScore W2062400487C55493867 @default.
- W2062400487 hasConceptScore W2062400487C86803240 @default.
- W2062400487 hasConceptScore W2062400487C95444343 @default.
- W2062400487 hasConceptScore W2062400487C98274493 @default.
- W2062400487 hasIssue "4" @default.