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- W2062417962 abstract "The role of cellular repair in radiation biology and therapy is reviewed from the standpoint of possible chemical inhibition as a means of radiosensitization. PLD repair inhibitors screened in cell culture system and DNA repair inhibitors in molecular system are reported. Among them some of PLD repair inhibitors such as 3'-deoxyadenosine, 3'-deoxyguanosine, β-arabinofuranosyladenine (ara-A) and their derivatives are shown to be effective radiosensitizers as well as chemosensitizers in experimental tumors. Preliminary results of clinical trial of ara-A in radio- and chemotherapy of the cancer are also presented." @default.
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- W2062417962 date "1984-01-01" @default.
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- W2062417962 title "PLD repair inhibitors as radiosensitizers" @default.
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