Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062445638> ?p ?o ?g. }
- W2062445638 endingPage "1629" @default.
- W2062445638 startingPage "1620" @default.
- W2062445638 abstract "Polymer-supported chiral organocatalysts, as well as most other forms of immobilized catalysts, are traditionally prepared by a postmodification approach where modified catalyst precursors are anchored onto prefabricated polymer beads. Herein, we report an alternative and more scalable approach where polymer-supported chiral enamine and iminium organocatalysts are prepared in a bottom-up fashion where methacrylic functional monomers are prepared in an entirely nonchromatographic manner and subsequently copolymerized with suitable comonomers to give cross-linked polymer beads. All syntheses have been conducted on multigram scale for all intermediates and finished polymer products, and the catalysts have proven successful in reactions taking place in solvents spanning a wide range of solvent polarity. While polymer-supported proline and prolineamides generally demonstrated excellent results and recycling robustness in asymmetric aldol reactions of ketones and benzaldehydes, the simplest type of Jørgensen/Hayashi diarylprolinol TMS-ether showed excellent selectivity, but rather sluggish reactivity in the Enders-type asymmetric cascade. The polymer-supported version of the first-generation MacMillan imidazolidinone had a pattern of reactivity very similar to that of the monomeric catalyst, but is too unstable to allow recycling." @default.
- W2062445638 created "2016-06-24" @default.
- W2062445638 creator A5052030211 @default.
- W2062445638 creator A5069067876 @default.
- W2062445638 creator A5073267919 @default.
- W2062445638 creator A5073300828 @default.
- W2062445638 creator A5084188265 @default.
- W2062445638 date "2010-02-08" @default.
- W2062445638 modified "2023-10-18" @default.
- W2062445638 title "A General Approach for Preparation of Polymer-Supported Chiral Organocatalysts via Acrylic Copolymerization" @default.
- W2062445638 cites W1542423148 @default.
- W2062445638 cites W1964237748 @default.
- W2062445638 cites W1967564407 @default.
- W2062445638 cites W1967861454 @default.
- W2062445638 cites W1968282668 @default.
- W2062445638 cites W1968332904 @default.
- W2062445638 cites W1970772463 @default.
- W2062445638 cites W1972174093 @default.
- W2062445638 cites W1978510424 @default.
- W2062445638 cites W1981149288 @default.
- W2062445638 cites W1988504082 @default.
- W2062445638 cites W1991390651 @default.
- W2062445638 cites W1997236349 @default.
- W2062445638 cites W1999136159 @default.
- W2062445638 cites W2002889273 @default.
- W2062445638 cites W2005664724 @default.
- W2062445638 cites W2010196527 @default.
- W2062445638 cites W2013092331 @default.
- W2062445638 cites W2015849672 @default.
- W2062445638 cites W2017790094 @default.
- W2062445638 cites W2018709993 @default.
- W2062445638 cites W2019138564 @default.
- W2062445638 cites W2021071888 @default.
- W2062445638 cites W2021157862 @default.
- W2062445638 cites W2024016071 @default.
- W2062445638 cites W2028598889 @default.
- W2062445638 cites W2040942636 @default.
- W2062445638 cites W2042434512 @default.
- W2062445638 cites W2046354043 @default.
- W2062445638 cites W2049258974 @default.
- W2062445638 cites W2050330817 @default.
- W2062445638 cites W2050620648 @default.
- W2062445638 cites W2054305392 @default.
- W2062445638 cites W2054930916 @default.
- W2062445638 cites W2055816746 @default.
- W2062445638 cites W2057664315 @default.
- W2062445638 cites W2057755142 @default.
- W2062445638 cites W2062355662 @default.
- W2062445638 cites W2062676186 @default.
- W2062445638 cites W2065014257 @default.
- W2062445638 cites W2065736341 @default.
- W2062445638 cites W2070750058 @default.
- W2062445638 cites W2072341703 @default.
- W2062445638 cites W2083698603 @default.
- W2062445638 cites W2085193807 @default.
- W2062445638 cites W2087274467 @default.
- W2062445638 cites W2091838088 @default.
- W2062445638 cites W2093338767 @default.
- W2062445638 cites W2098430907 @default.
- W2062445638 cites W2103118742 @default.
- W2062445638 cites W2103313675 @default.
- W2062445638 cites W2109366906 @default.
- W2062445638 cites W2111280484 @default.
- W2062445638 cites W2118093092 @default.
- W2062445638 cites W2120560286 @default.
- W2062445638 cites W2124861960 @default.
- W2062445638 cites W2127634213 @default.
- W2062445638 cites W2147744446 @default.
- W2062445638 cites W2155678338 @default.
- W2062445638 cites W2157167787 @default.
- W2062445638 cites W2159771831 @default.
- W2062445638 cites W2163858331 @default.
- W2062445638 cites W2165539982 @default.
- W2062445638 cites W2172247375 @default.
- W2062445638 cites W2320556745 @default.
- W2062445638 cites W2326169069 @default.
- W2062445638 cites W2330319949 @default.
- W2062445638 cites W2552822738 @default.
- W2062445638 cites W2949653989 @default.
- W2062445638 cites W2950266152 @default.
- W2062445638 cites W2950338315 @default.
- W2062445638 cites W2950822004 @default.
- W2062445638 cites W2951375028 @default.
- W2062445638 cites W2951394064 @default.
- W2062445638 cites W2951952364 @default.
- W2062445638 cites W2952205889 @default.
- W2062445638 cites W2952649818 @default.
- W2062445638 cites W2952782850 @default.
- W2062445638 cites W2952794327 @default.
- W2062445638 cites W2953193857 @default.
- W2062445638 cites W342835521 @default.
- W2062445638 cites W4242488137 @default.
- W2062445638 cites W4246528915 @default.
- W2062445638 cites W4376848524 @default.
- W2062445638 cites W60061431 @default.
- W2062445638 cites W2058763796 @default.
- W2062445638 doi "https://doi.org/10.1021/jo902585j" @default.
- W2062445638 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20141122" @default.