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- W2062452317 abstract "Methyltetrahydrofolic acid, formyltetrahydrofolic acid, folic acid and dihydrofolic acid were injected intravitreally into the eyes of chickens. No short-term or long-term signs of neurotoxicity were observed, even when doses 100-200 times those at which kainic acid produces clear neurotoxic effects were injected. The folic acid derivatives neither inhibited nor potentiated the neurotoxic effects. Thus no support is given to the suggestion that folic acid and its derivatives may act as kainic acid agonists or antagonists, even though the receptors involved in kainic acid-induced neurotoxicity appear to be of the kainic acid rather than quisqualic acid or N-methyl-D-aspartic acid type." @default.
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- W2062452317 date "1982-12-01" @default.
- W2062452317 modified "2023-09-25" @default.
- W2062452317 title "Folic acid derivatives do not reproduce the neurotoxic effects of kainic acid on chicken retina" @default.
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- W2062452317 doi "https://doi.org/10.1016/0304-3940(82)90094-5" @default.
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