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• W2062482933 abstract "Background: In areas where both tuberculosis and Crohn's disease are common, colonic manifestations may be similar. Despite availability of a battery of tests, it may be difficult to distinguish between these conditions. Aim: To assess clinical features and endoscopy findings that could potentially differentiate colonic tuberculosis from Crohn's colitis. Materials and method: Patients included in this study were those presenting between June 2000 and March 2004 with a definite histologic diagnosis of tuberculosis or Crohn's; or those in whom treatment with anti-tubercular therapy resulted in clinical and/ or endoscopic resolution. These patients were retrospectively reviewed to analyze clinical features and colonoscopic findings Results: 27 patients with colonic tuberculosis and 80 patients with Crohn's disease met the inclusion criteria. Patients with Crohn's disease presented significantly more commonly with diarrhea (83%), rectal bleeding (59%), melena (28%) and prior history of perianal disease (28%). Tubercular patients tended to have abdominal pain more commonly (96%). On colonoscopy of tuberculosis patients, contiguous ileocaecal involvement was significantly more common (74%) and left colon involvement significantly less common. The ulcerations tended to be transverse. On the contrary, skip lesions, rectal and left colonic involvement and linear ulcers were significantly more common in Crohn's disease. Conclusion: Clinical presentation with diarrhea, rectal bleed or malena, previous history of perianal disease and colonoscopic left colonic involvement, skip lesions and linear ulcers are more commonly seen in Crohn's disease. Patients presenting predominantly with abdominal pain and colonoscopic features of ileocecal involvement are more often seen in colonic tuberculosis. Background: In areas where both tuberculosis and Crohn's disease are common, colonic manifestations may be similar. Despite availability of a battery of tests, it may be difficult to distinguish between these conditions. Aim: To assess clinical features and endoscopy findings that could potentially differentiate colonic tuberculosis from Crohn's colitis. Materials and method: Patients included in this study were those presenting between June 2000 and March 2004 with a definite histologic diagnosis of tuberculosis or Crohn's; or those in whom treatment with anti-tubercular therapy resulted in clinical and/ or endoscopic resolution. These patients were retrospectively reviewed to analyze clinical features and colonoscopic findings Results: 27 patients with colonic tuberculosis and 80 patients with Crohn's disease met the inclusion criteria. Patients with Crohn's disease presented significantly more commonly with diarrhea (83%), rectal bleeding (59%), melena (28%) and prior history of perianal disease (28%). Tubercular patients tended to have abdominal pain more commonly (96%). On colonoscopy of tuberculosis patients, contiguous ileocaecal involvement was significantly more common (74%) and left colon involvement significantly less common. The ulcerations tended to be transverse. On the contrary, skip lesions, rectal and left colonic involvement and linear ulcers were significantly more common in Crohn's disease. Conclusion: Clinical presentation with diarrhea, rectal bleed or malena, previous history of perianal disease and colonoscopic left colonic involvement, skip lesions and linear ulcers are more commonly seen in Crohn's disease. Patients presenting predominantly with abdominal pain and colonoscopic features of ileocecal involvement are more often seen in colonic tuberculosis." @default.
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• W2062482933 date "2005-04-01" @default.
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• W2062482933 title "Clinicocolonoscopic Differentiation of Tuberculosis From Crohn's Disease" @default.
• W2062482933 doi "https://doi.org/10.1016/s0016-5107(05)01382-9" @default.
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