Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062530890> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2062530890 endingPage "163" @default.
- W2062530890 startingPage "160" @default.
- W2062530890 abstract "Merkel cell carcinomas (MCC) belong to the family of neuroendocrine tumors. In addition to other markers, they express somatostatin receptors. They are uncommon, highly malignant skin tumors with an aggressive clinical course. They develop in sun-exposed areas of the skin, mostly in elderly patients. In addition to frequent locoregional recurrences, there is a high incidence of distant metastases. Treatment is stage dependent and consists of operation and chemo- and/or radiotherapy, respectively. The advanced age of patients often impedes adequate therapy. (90)Y-DOTATOC is a novel radiolabeled somatostatin analogue containing the active octapeptide of somatostatin. It is very well tolerated and offers the option of treating somatostatin receptor-positive tumors by targeted radiotherapy. We report the case of an 83-year-old woman with recurrent MCC of the left cheek. The primary tumor and several relapses were treated with surgery and locoregional radiotherapy. After the 3rd relapse, she was treated 4 times with (90)Y-DOTATOC and two complete remissions were achieved. The fourth administration after the 2nd relapse was ineffective and conventional chemotherapy was started. There were no side effects of the (90)Y-DOTATOC. We conclude that due to its good tolerability, (90)Y-DOTATOC therapy should be evaluated further as a new therapy for somatostatin receptor-positive MCC." @default.
- W2062530890 created "2016-06-24" @default.
- W2062530890 creator A5011868198 @default.
- W2062530890 creator A5013094846 @default.
- W2062530890 creator A5060986576 @default.
- W2062530890 creator A5061360488 @default.
- W2062530890 creator A5071517999 @default.
- W2062530890 creator A5089948389 @default.
- W2062530890 date "2004-01-01" @default.
- W2062530890 modified "2023-10-18" @default.
- W2062530890 title "Successful Targeted Radiotherapy with <sup>90</sup>Y-DOTATOC in a Patient with Merkel Cell Carcinoma" @default.
- W2062530890 cites W1902952770 @default.
- W2062530890 cites W1935825021 @default.
- W2062530890 cites W1984622272 @default.
- W2062530890 cites W1993412014 @default.
- W2062530890 cites W2001776535 @default.
- W2062530890 cites W2024170734 @default.
- W2062530890 cites W2026302622 @default.
- W2062530890 cites W2041342426 @default.
- W2062530890 cites W2052266670 @default.
- W2062530890 cites W2078063184 @default.
- W2062530890 cites W2079012954 @default.
- W2062530890 cites W2109049048 @default.
- W2062530890 cites W2334493919 @default.
- W2062530890 cites W2917068635 @default.
- W2062530890 cites W4230131648 @default.
- W2062530890 cites W4230829695 @default.
- W2062530890 cites W4254233664 @default.
- W2062530890 cites W4256411162 @default.
- W2062530890 cites W4296766361 @default.
- W2062530890 doi "https://doi.org/10.1159/000077443" @default.
- W2062530890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15138369" @default.
- W2062530890 hasPublicationYear "2004" @default.
- W2062530890 type Work @default.
- W2062530890 sameAs 2062530890 @default.
- W2062530890 citedByCount "44" @default.
- W2062530890 countsByYear W20625308902012 @default.
- W2062530890 countsByYear W20625308902013 @default.
- W2062530890 countsByYear W20625308902014 @default.
- W2062530890 countsByYear W20625308902015 @default.
- W2062530890 countsByYear W20625308902017 @default.
- W2062530890 countsByYear W20625308902018 @default.
- W2062530890 countsByYear W20625308902019 @default.
- W2062530890 countsByYear W20625308902021 @default.
- W2062530890 countsByYear W20625308902022 @default.
- W2062530890 crossrefType "journal-article" @default.
- W2062530890 hasAuthorship W2062530890A5011868198 @default.
- W2062530890 hasAuthorship W2062530890A5013094846 @default.
- W2062530890 hasAuthorship W2062530890A5060986576 @default.
- W2062530890 hasAuthorship W2062530890A5061360488 @default.
- W2062530890 hasAuthorship W2062530890A5071517999 @default.
- W2062530890 hasAuthorship W2062530890A5089948389 @default.
- W2062530890 hasConcept C126322002 @default.
- W2062530890 hasConcept C143998085 @default.
- W2062530890 hasConcept C197934379 @default.
- W2062530890 hasConcept C2776297358 @default.
- W2062530890 hasConcept C2776694085 @default.
- W2062530890 hasConcept C2777546739 @default.
- W2062530890 hasConcept C2778342957 @default.
- W2062530890 hasConcept C2778375690 @default.
- W2062530890 hasConcept C2779066768 @default.
- W2062530890 hasConcept C2780291066 @default.
- W2062530890 hasConcept C509974204 @default.
- W2062530890 hasConcept C71924100 @default.
- W2062530890 hasConcept C80115893 @default.
- W2062530890 hasConceptScore W2062530890C126322002 @default.
- W2062530890 hasConceptScore W2062530890C143998085 @default.
- W2062530890 hasConceptScore W2062530890C197934379 @default.
- W2062530890 hasConceptScore W2062530890C2776297358 @default.
- W2062530890 hasConceptScore W2062530890C2776694085 @default.
- W2062530890 hasConceptScore W2062530890C2777546739 @default.
- W2062530890 hasConceptScore W2062530890C2778342957 @default.
- W2062530890 hasConceptScore W2062530890C2778375690 @default.
- W2062530890 hasConceptScore W2062530890C2779066768 @default.
- W2062530890 hasConceptScore W2062530890C2780291066 @default.
- W2062530890 hasConceptScore W2062530890C509974204 @default.
- W2062530890 hasConceptScore W2062530890C71924100 @default.
- W2062530890 hasConceptScore W2062530890C80115893 @default.
- W2062530890 hasIssue "2" @default.
- W2062530890 hasLocation W20625308901 @default.
- W2062530890 hasLocation W20625308902 @default.
- W2062530890 hasOpenAccess W2062530890 @default.
- W2062530890 hasPrimaryLocation W20625308901 @default.
- W2062530890 hasRelatedWork W1964078768 @default.
- W2062530890 hasRelatedWork W1975786744 @default.
- W2062530890 hasRelatedWork W1995669920 @default.
- W2062530890 hasRelatedWork W2062530890 @default.
- W2062530890 hasRelatedWork W2144003347 @default.
- W2062530890 hasRelatedWork W2321118795 @default.
- W2062530890 hasRelatedWork W2396241214 @default.
- W2062530890 hasRelatedWork W2415522692 @default.
- W2062530890 hasRelatedWork W2794786437 @default.
- W2062530890 hasRelatedWork W3017309227 @default.
- W2062530890 hasVolume "66" @default.
- W2062530890 isParatext "false" @default.
- W2062530890 isRetracted "false" @default.
- W2062530890 magId "2062530890" @default.
- W2062530890 workType "article" @default.