Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062551937> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W2062551937 abstract "Self-assembly of 13 nm gold nanoparticles (AuNPs) engineered into 2D structures in solution using DNA tiles for their possible use for gene delivery and photothermal therapy is reported. The two different DNA tiles were constructed and the AuNPs coated with oligonucleotides possessing complementary sequence from the free ends were hybridized with the sticky ends of the tiles. The DNA tiles were bind to each other by mixing the tile structures without a heating and cooling step. The constructed nanostructures were 5 to 7 DNA tiles long since heat was not used to elongate them. When the DNA tiles were bound to the AuNPs, it was observed that AuNPs tend to stay in close proximity by filling the gaps between tiles. The stability of the constructed structures was tested against DNase, a DNA cleaving enzyme, for possible applications for gene delivery and photothermal therapy. It was found that the AuNP bound DNA tile structures resist the DNase cleavage up to eighty percent. Due to the presence of the AuNPs in the structure, the enzyme cannot bind to DNA sequences and this increases the DNA tile structures’ stability." @default.
- W2062551937 created "2016-06-24" @default.
- W2062551937 creator A5041051675 @default.
- W2062551937 creator A5043094524 @default.
- W2062551937 creator A5043399178 @default.
- W2062551937 date "2012-01-25" @default.
- W2062551937 modified "2023-10-15" @default.
- W2062551937 title "2D Gold Nanoparticle Structures Engineered Through DNA Tiles for Delivery and Therapy" @default.
- W2062551937 doi "https://doi.org/10.5101/nbe.v4i1.p17-22" @default.
- W2062551937 hasPublicationYear "2012" @default.
- W2062551937 type Work @default.
- W2062551937 sameAs 2062551937 @default.
- W2062551937 citedByCount "4" @default.
- W2062551937 countsByYear W20625519372012 @default.
- W2062551937 countsByYear W20625519372014 @default.
- W2062551937 countsByYear W20625519372016 @default.
- W2062551937 crossrefType "journal-article" @default.
- W2062551937 hasAuthorship W2062551937A5041051675 @default.
- W2062551937 hasAuthorship W2062551937A5043094524 @default.
- W2062551937 hasAuthorship W2062551937A5043399178 @default.
- W2062551937 hasBestOaLocation W20625519371 @default.
- W2062551937 hasConcept C104819515 @default.
- W2062551937 hasConcept C155672457 @default.
- W2062551937 hasConcept C171250308 @default.
- W2062551937 hasConcept C192562407 @default.
- W2062551937 hasConceptScore W2062551937C104819515 @default.
- W2062551937 hasConceptScore W2062551937C155672457 @default.
- W2062551937 hasConceptScore W2062551937C171250308 @default.
- W2062551937 hasConceptScore W2062551937C192562407 @default.
- W2062551937 hasIssue "1" @default.
- W2062551937 hasLocation W20625519371 @default.
- W2062551937 hasOpenAccess W2062551937 @default.
- W2062551937 hasPrimaryLocation W20625519371 @default.
- W2062551937 hasRelatedWork W1659871537 @default.
- W2062551937 hasRelatedWork W2058631687 @default.
- W2062551937 hasRelatedWork W2071383841 @default.
- W2062551937 hasRelatedWork W2156611380 @default.
- W2062551937 hasRelatedWork W2414615721 @default.
- W2062551937 hasRelatedWork W2967492500 @default.
- W2062551937 hasRelatedWork W3012559914 @default.
- W2062551937 hasRelatedWork W3114424702 @default.
- W2062551937 hasRelatedWork W4248003285 @default.
- W2062551937 hasRelatedWork W31250680 @default.
- W2062551937 hasVolume "4" @default.
- W2062551937 isParatext "false" @default.
- W2062551937 isRetracted "false" @default.
- W2062551937 magId "2062551937" @default.
- W2062551937 workType "article" @default.