Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062577085> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2062577085 endingPage "192" @default.
- W2062577085 startingPage "183" @default.
- W2062577085 abstract "Contraction regulates the myosin content and the rate of myosin synthesis in cultured neonatal rat heart cells. To further explore the mechanism for this regulation we examined various parameters of RNA content and RNA synthesis in contacting versus noncontracting myocytes. While contraction stimulated myosin heavy chain (MHC) synthesis by 72% compared to that of KCl-arrested cells, simultaneous analyses of polysome profiles were no different under the two culture conditions. Incorporation of [3H]uridine monophosphate into cellular RNA revealed no change in the rate of total RNA or ribosomal subunits synthesis. In vitro translation of cellular RNA yielded similar incorporation of [35S]methionine into trichloroacetic acid precipitable protein. Specific transcription of the MHC gene was examined by dot-blot analysis and was unaltered by contraction. Northern blot analysis of the MHC sequences detected by a cDNA probe revealed an mRNA sequence corresponding to a molecular weight of approximately 30 S. These data suggest that RNA synthesis and RNA content are unaltered by contraction in cultured heart cells and therefore the changes in myosin synthesis may be mediated at a post-transcriptional control level." @default.
- W2062577085 created "2016-06-24" @default.
- W2062577085 creator A5030426564 @default.
- W2062577085 creator A5036058899 @default.
- W2062577085 creator A5056104537 @default.
- W2062577085 date "1987-11-01" @default.
- W2062577085 modified "2023-10-17" @default.
- W2062577085 title "Regulation of cardiac myosin synthesis: Studies of RNA content in cultured heart cells" @default.
- W2062577085 cites W1511926315 @default.
- W2062577085 cites W1514158683 @default.
- W2062577085 cites W1551002057 @default.
- W2062577085 cites W1577871794 @default.
- W2062577085 cites W1588766342 @default.
- W2062577085 cites W1609528353 @default.
- W2062577085 cites W1970403529 @default.
- W2062577085 cites W1974744126 @default.
- W2062577085 cites W1979717755 @default.
- W2062577085 cites W1992939744 @default.
- W2062577085 cites W1995273385 @default.
- W2062577085 cites W1995486522 @default.
- W2062577085 cites W2012591372 @default.
- W2062577085 cites W2012619752 @default.
- W2062577085 cites W2038564114 @default.
- W2062577085 cites W2053624118 @default.
- W2062577085 cites W2060503440 @default.
- W2062577085 cites W2081764298 @default.
- W2062577085 cites W2087896205 @default.
- W2062577085 cites W2089582790 @default.
- W2062577085 cites W2102129370 @default.
- W2062577085 cites W2132149497 @default.
- W2062577085 cites W2133954863 @default.
- W2062577085 cites W2161906616 @default.
- W2062577085 cites W2410649504 @default.
- W2062577085 doi "https://doi.org/10.1016/0014-4827(87)90344-2" @default.
- W2062577085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3678378" @default.
- W2062577085 hasPublicationYear "1987" @default.
- W2062577085 type Work @default.
- W2062577085 sameAs 2062577085 @default.
- W2062577085 citedByCount "9" @default.
- W2062577085 crossrefType "journal-article" @default.
- W2062577085 hasAuthorship W2062577085A5030426564 @default.
- W2062577085 hasAuthorship W2062577085A5036058899 @default.
- W2062577085 hasAuthorship W2062577085A5056104537 @default.
- W2062577085 hasConcept C104317684 @default.
- W2062577085 hasConcept C105580179 @default.
- W2062577085 hasConcept C153911025 @default.
- W2062577085 hasConcept C177707886 @default.
- W2062577085 hasConcept C3675279 @default.
- W2062577085 hasConcept C55493867 @default.
- W2062577085 hasConcept C65666806 @default.
- W2062577085 hasConcept C67705224 @default.
- W2062577085 hasConcept C67905577 @default.
- W2062577085 hasConcept C6997183 @default.
- W2062577085 hasConcept C86803240 @default.
- W2062577085 hasConcept C88478588 @default.
- W2062577085 hasConcept C95444343 @default.
- W2062577085 hasConceptScore W2062577085C104317684 @default.
- W2062577085 hasConceptScore W2062577085C105580179 @default.
- W2062577085 hasConceptScore W2062577085C153911025 @default.
- W2062577085 hasConceptScore W2062577085C177707886 @default.
- W2062577085 hasConceptScore W2062577085C3675279 @default.
- W2062577085 hasConceptScore W2062577085C55493867 @default.
- W2062577085 hasConceptScore W2062577085C65666806 @default.
- W2062577085 hasConceptScore W2062577085C67705224 @default.
- W2062577085 hasConceptScore W2062577085C67905577 @default.
- W2062577085 hasConceptScore W2062577085C6997183 @default.
- W2062577085 hasConceptScore W2062577085C86803240 @default.
- W2062577085 hasConceptScore W2062577085C88478588 @default.
- W2062577085 hasConceptScore W2062577085C95444343 @default.
- W2062577085 hasIssue "1" @default.
- W2062577085 hasLocation W20625770851 @default.
- W2062577085 hasLocation W20625770852 @default.
- W2062577085 hasOpenAccess W2062577085 @default.
- W2062577085 hasPrimaryLocation W20625770851 @default.
- W2062577085 hasRelatedWork W1558850036 @default.
- W2062577085 hasRelatedWork W1930954292 @default.
- W2062577085 hasRelatedWork W1966344818 @default.
- W2062577085 hasRelatedWork W1986198964 @default.
- W2062577085 hasRelatedWork W2014617051 @default.
- W2062577085 hasRelatedWork W2030736202 @default.
- W2062577085 hasRelatedWork W2060949829 @default.
- W2062577085 hasRelatedWork W2075782744 @default.
- W2062577085 hasRelatedWork W2402836686 @default.
- W2062577085 hasRelatedWork W2476347230 @default.
- W2062577085 hasVolume "173" @default.
- W2062577085 isParatext "false" @default.
- W2062577085 isRetracted "false" @default.
- W2062577085 magId "2062577085" @default.
- W2062577085 workType "article" @default.