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• W2062600825 abstract "A 1660 g, male infant was born at 32 weeks gestation to a 34-year-old gravida 2 para 1 mother. Pregnancy was complicated by cervical incompetence, and the infant was born via cesarean delivery. The mother denied having taken any drugs or being exposed to radiographs. There was no family history of congenital anomalies or consanguinity. On admission to the Neonatal Intensive Care Unit, the infant was noted to have a thin, threadlike band of tissue vertically connecting the left upper and lower eyelids (Figures 1 and 2). The rest of the physical examination was perfectly normal and a detailed assessment, including cranial ultrasound, echocardiography, and otoacoustic emission screening failed to reveal any other congenital anomalies.Figure 2Thin fibrous band, vertically connecting the left eyelids.View Large Image Figure ViewerDownload Hi-res image Download (PPT) The ophthalmologic examination revealed a single adhesion in the middle portion of the left eyelid margins. With manual retraction of the eyelids, the affected eye's anterior segment and fundus seemed normal (Figure 3). An incision to the band tissue was made with a surgical scissors with minimal hemorrhage (Video; available at www.jpeds.com). The rest of this premature infant's course was totally normal with unremarkable detailed ophthalmologic examinations in the follow-ups. Ankyloblepharon filiforme adnatum (AFA) is defined by partial eyelid fusion with an extensile band of fibrous tissue vertically attached to upper and lower eyelids. AFA, in isolation, is of unknown etiology with an incidence of 4.4 per 100 000 births. Nonsyndromic cases might be associated with central nervous system or cardiovascular malformations.1Jain S. Atkinson A.J. Hopkisson B. Ankyloblepharon filiforme adnatum.Br J Ophthalmol. 1997; 81: 705Crossref Google Scholar Although it may appear as a solitary anomaly, it can also be associated with a wide spectrum of systemic malformations, such as Hay-Wells syndrome, also known as ankyloblepharon-ectodermal dysplasia-clefting syndrome, curly hair-ankyloblepharon-nail dysplasia syndrome, and Edwards syndrome (trisomy 18). Furthermore, it might be associated with hydrocephalus, glaucoma, and cardiac defects.2Sharkey D. Marlow N. Stokes J. Ankyloblepharon filiforme adnatum.J Pediatr. 2008; 152: 594Abstract Full Text Full Text PDF PubMed Scopus (10) Google Scholar, 3Martinez-Ortiz A. Garrido-Contreras V. Perez-Martinez A. Ardanaz-Aldave A. Zubieta-Garciandia A. Elso-Tartas J. Ankyloblepharon filiforme adnatum: presentation of a case.Pediatr Dermatol. 2012; 27: 207-208Crossref Scopus (1) Google Scholar AFA is diagnosed clinically with its unique presentation, and the treatment consists of simple surgical resection of the fibrous bands, which might allow detailed ophthalmologic examination and alleviate parental stress. The major practical importance of this anomaly is that the physician should be aware of the possible presence of other congenital anomalies.1Jain S. Atkinson A.J. Hopkisson B. Ankyloblepharon filiforme adnatum.Br J Ophthalmol. 1997; 81: 705Crossref Google Scholar Download .avi (11.67 MB) Help with avi files Video" @default.
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• W2062600825 date "2013-01-01" @default.
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• W2062600825 title "A Stitched Eye in the Newborn: Ankyloblepharon Filiforme Adnatum" @default.
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• W2062600825 doi "https://doi.org/10.1016/j.jpeds.2012.08.041" @default.
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