Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062602011> ?p ?o ?g. }
- W2062602011 endingPage "151" @default.
- W2062602011 startingPage "139" @default.
- W2062602011 abstract "Caveolae are morphologically evident as omega-shaped invaginations of the plasma membrane with a diameter of 50–100 nm. They may also exist in a variety of other forms including flattened domains indistinguishable from the plasma membrane itself. At least in some cell types caveolae undertake transport functions including that of the endocytic and transcytotic movement of macromolecules, and indeed microbes and microbial toxins. Opportunities exist for basic and applied investigators working within the pharmaceutical sciences to exploit caveolae membrane interactions with the aim to develop of novel cellular or transcellular drug delivery strategies. This overview article will provide: pertinent information on the biology of the caveolae membrane system; review the various caveolae isolation methods; highlight some of the literature evidence showing that caveolae are functional with regard to macromolecule transport; discuss the role that caveolae could fulfill in the pulmonary absorption of therapeutic proteins from alveolar airspace to capillary blood following inhalational drug delivery, and finally review some very recent work showing proof-of-principle that caveolae domains can be targeted in a tissue-specific manner with highly selective ligands." @default.
- W2062602011 created "2016-06-24" @default.
- W2062602011 creator A5031279238 @default.
- W2062602011 creator A5038131272 @default.
- W2062602011 creator A5040308280 @default.
- W2062602011 creator A5052464532 @default.
- W2062602011 creator A5068115915 @default.
- W2062602011 date "2003-02-01" @default.
- W2062602011 modified "2023-10-18" @default.
- W2062602011 title "Targeting caveolae for vesicular drug transport" @default.
- W2062602011 cites W107714425 @default.
- W2062602011 cites W1258111398 @default.
- W2062602011 cites W139442493 @default.
- W2062602011 cites W1549194476 @default.
- W2062602011 cites W1575798288 @default.
- W2062602011 cites W1598968710 @default.
- W2062602011 cites W1643087207 @default.
- W2062602011 cites W1963556560 @default.
- W2062602011 cites W1963952319 @default.
- W2062602011 cites W1967289387 @default.
- W2062602011 cites W1974043466 @default.
- W2062602011 cites W1980773456 @default.
- W2062602011 cites W1983949401 @default.
- W2062602011 cites W1995150314 @default.
- W2062602011 cites W1996219643 @default.
- W2062602011 cites W1999743098 @default.
- W2062602011 cites W2012690424 @default.
- W2062602011 cites W2019862207 @default.
- W2062602011 cites W2022561687 @default.
- W2062602011 cites W2032190558 @default.
- W2062602011 cites W2046774437 @default.
- W2062602011 cites W2049215266 @default.
- W2062602011 cites W2050465028 @default.
- W2062602011 cites W2059159382 @default.
- W2062602011 cites W2059895279 @default.
- W2062602011 cites W2060481671 @default.
- W2062602011 cites W2062315382 @default.
- W2062602011 cites W2064754325 @default.
- W2062602011 cites W2066812102 @default.
- W2062602011 cites W2068800887 @default.
- W2062602011 cites W2069444054 @default.
- W2062602011 cites W2074753255 @default.
- W2062602011 cites W2080238905 @default.
- W2062602011 cites W2088432812 @default.
- W2062602011 cites W2088638510 @default.
- W2062602011 cites W2088812802 @default.
- W2062602011 cites W2095483664 @default.
- W2062602011 cites W2105943425 @default.
- W2062602011 cites W2111833940 @default.
- W2062602011 cites W2112465136 @default.
- W2062602011 cites W2117468682 @default.
- W2062602011 cites W2119569928 @default.
- W2062602011 cites W2121936687 @default.
- W2062602011 cites W2126392303 @default.
- W2062602011 cites W2133388060 @default.
- W2062602011 cites W2138568868 @default.
- W2062602011 cites W2156590312 @default.
- W2062602011 cites W2160670356 @default.
- W2062602011 cites W2161484620 @default.
- W2062602011 cites W2163790379 @default.
- W2062602011 cites W2164957471 @default.
- W2062602011 cites W2165467938 @default.
- W2062602011 cites W2464439230 @default.
- W2062602011 cites W4245394973 @default.
- W2062602011 cites W4248349873 @default.
- W2062602011 doi "https://doi.org/10.1016/s0168-3659(02)00358-9" @default.
- W2062602011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12618030" @default.
- W2062602011 hasPublicationYear "2003" @default.
- W2062602011 type Work @default.
- W2062602011 sameAs 2062602011 @default.
- W2062602011 citedByCount "38" @default.
- W2062602011 countsByYear W20626020112012 @default.
- W2062602011 countsByYear W20626020112013 @default.
- W2062602011 countsByYear W20626020112014 @default.
- W2062602011 countsByYear W20626020112015 @default.
- W2062602011 countsByYear W20626020112016 @default.
- W2062602011 countsByYear W20626020112017 @default.
- W2062602011 countsByYear W20626020112021 @default.
- W2062602011 countsByYear W20626020112022 @default.
- W2062602011 countsByYear W20626020112023 @default.
- W2062602011 crossrefType "journal-article" @default.
- W2062602011 hasAuthorship W2062602011A5031279238 @default.
- W2062602011 hasAuthorship W2062602011A5038131272 @default.
- W2062602011 hasAuthorship W2062602011A5040308280 @default.
- W2062602011 hasAuthorship W2062602011A5052464532 @default.
- W2062602011 hasAuthorship W2062602011A5068115915 @default.
- W2062602011 hasConcept C120882062 @default.
- W2062602011 hasConcept C1491633281 @default.
- W2062602011 hasConcept C178790620 @default.
- W2062602011 hasConcept C185350488 @default.
- W2062602011 hasConcept C185592680 @default.
- W2062602011 hasConcept C2779820397 @default.
- W2062602011 hasConcept C28005876 @default.
- W2062602011 hasConcept C41625074 @default.
- W2062602011 hasConcept C49866891 @default.
- W2062602011 hasConcept C55493867 @default.
- W2062602011 hasConcept C60903277 @default.
- W2062602011 hasConcept C62478195 @default.