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- W2062606837 abstract "Letters15 May 1995Dapsone in Thrombocytopenia of the Antiphospholipid Antibody SyndromePhilippe Lesprit, Bertrand Godeau, and Bertrand WechslerPhilippe LespritSearch for more papers by this author, Bertrand GodeauSearch for more papers by this author, and Bertrand WechslerSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-10-199505150-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Kavanaugh [1] recently reported the beneficial effect of danazol on thrombocytopenia in a patient with the antiphospholipid antibody syndrome.We describe a woman with thrombocytopenia associated with primary antiphospholipid syndrome who responded to dapsone therapy. Her medical history included two fetal losses. In December 1993, profound thrombocytopenia (platelet count, 10 × 109/L) was seen with another spontaneous abortion. Treatment with prednisone (80 mg daily) was started, and her platelet count transiently increased to 37 × 109/L. She was hospitalized in our unit in February 1994. Physical examination was unremarkable except for ecchymotic purpura. Prednisone (1 mg/kg body ...References1. Kavanaugh A. Danazol therapy in thrombocytopenia associated with the antiphospholipid antibody syndrome. Ann Intern Med. 1994; 121:767-8. Google Scholar2. Durand JM, Lefevre P, Hovette P, Mongin M, Soubeyrand J. Dapsone for idiopathic autoimmune thrombocytopenic purpura in elderly patients. Br J Haematol. 1991; 78:459-63. Google Scholar3. Durand JM, Lefevre P, Hovette P, Issifi S, Mongin M. Dapsone for thrombocytopenic purpura related to human immunodeficiency virus infection. Am J Med. 1991; 90:675-7. Google Scholar4. Godeau B, Oksenhendler E, Bierling P. Dapsone for autoimmune thrombocytopenic purpura. Am J Hematol. 1993; 44:70-2. Google Scholar5. Durand JM, Lefevre P, Kaplanski G, Cretel E, Mongin M, Soubeyrand J. Correction of thrombocytopenia with dapsone in the primary antiphospholipid syndrome. J Rheumatol. 1993; 20:1777-8. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCryptic conspirators: a conversation about thrombocytopenia and antiphospholipid syndromeEffects of a Novel Pyridylsulphonyl Thiazole Derivative, FR115092, on Autoimmune and Mitomycin C-induced Thrombycytopenia in MiceThe Hematologic Manifestations of the Antiphospholipid SyndromePurpura thrombopénique auto-immun 15 May 1995Volume 122, Issue 10Page: 802KeywordsAntibodiesAntiphospholipid syndromeDrugsElderlyEnzyme linked immunosorbent assayHIVIdiopathic thrombocytopenic purpuraMiscarriagePlateletsResearch laboratories Issue Published: 15 May 1995 CopyrightCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ..." @default.
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- W2062606837 date "1995-05-15" @default.
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- W2062606837 title "Dapsone in Thrombocytopenia of the Antiphospholipid Antibody Syndrome" @default.
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