FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062655152> ?p ?o ?g. }

• W2062655152 abstract "Antidepressant use has been associated with cognitive impairment in older persons. We sought to examine whether this association might reflect an indication bias.A total of 544 community-dwelling hypertensive men aged ≥65 years completed the Hopkins Verbal Learning Test at baseline and 1 year. Antidepressant medications were ascertained by the use of medical records. Potential confounding by indications was examined by adjusting for depression-related diagnoses and severity of depression symptoms using multiple linear regression, a propensity score, and a structural equation model (SEM).Before adjusting for the indications, a one unit cumulative exposure to antidepressants was associated with -1.00 (95% confidence interval [CI], -1.94, -0.06) point lower HVLT score. After adjusting for the indications using multiple linear regression or a propensity score, the association diminished to -0.48 (95% CI, -0.62, 1.58) and -0.58 (95% CI, -0.60, 1.58), respectively. The most clinical interpretable empirical SEM with adequate fit involves both direct and indirect paths of the two indications. Depression-related diagnoses and depression symptoms significantly predict antidepressant use (p < .05). Their total standardized path coefficients on Hopkins Verbal Learning Test score were twice (0.073) or as large (0.034) as the antidepressant use (0.035).The apparent association between antidepressant use and memory deficit in older persons may be confounded by indications. SEM offers a heuristic empirical method for examining confounding by indications but not quantitatively superior bias reduction compared with conventional methods." @default.
• W2062655152 created "2016-06-24" @default.
• W2062655152 creator A5032254200 @default.
• W2062655152 creator A5035221383 @default.
• W2062655152 creator A5038171056 @default.
• W2062655152 creator A5063600149 @default.
• W2062655152 date "2012-01-01" @default.
• W2062655152 modified "2023-09-23" @default.
• W2062655152 title "Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods" @default.
• W2062655152 cites W1565240145 @default.
• W2062655152 cites W1570060061 @default.
• W2062655152 cites W1643369756 @default.
• W2062655152 cites W1665332082 @default.
• W2062655152 cites W1917852220 @default.
• W2062655152 cites W1966624434 @default.
• W2062655152 cites W1975699010 @default.
• W2062655152 cites W1978204374 @default.
• W2062655152 cites W1987459273 @default.
• W2062655152 cites W1993243484 @default.
• W2062655152 cites W2000445173 @default.
• W2062655152 cites W2013831701 @default.
• W2062655152 cites W2020262183 @default.
• W2062655152 cites W2037135054 @default.
• W2062655152 cites W2042578688 @default.
• W2062655152 cites W2058496298 @default.
• W2062655152 cites W2063548620 @default.
• W2062655152 cites W2064616280 @default.
• W2062655152 cites W2071509654 @default.
• W2062655152 cites W2073225472 @default.
• W2062655152 cites W2089679462 @default.
• W2062655152 cites W2100039954 @default.
• W2062655152 cites W2104057213 @default.
• W2062655152 cites W2112778345 @default.
• W2062655152 cites W2121298241 @default.
• W2062655152 cites W2132940371 @default.
• W2062655152 cites W2136670164 @default.
• W2062655152 cites W2142495742 @default.
• W2062655152 cites W2150291618 @default.
• W2062655152 cites W2159011576 @default.
• W2062655152 cites W2162159672 @default.
• W2062655152 cites W2169294797 @default.
• W2062655152 cites W2414167269 @default.
• W2062655152 cites W2900927010 @default.
• W2062655152 cites W30500643 @default.
• W2062655152 cites W1996530279 @default.
• W2062655152 doi "https://doi.org/10.1016/j.annepidem.2011.10.004" @default.
• W2062655152 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4054866" @default.
• W2062655152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22037381" @default.
• W2062655152 hasPublicationYear "2012" @default.
• W2062655152 type Work @default.
• W2062655152 sameAs 2062655152 @default.
• W2062655152 citedByCount "6" @default.
• W2062655152 countsByYear W20626551522012 @default.
• W2062655152 countsByYear W20626551522013 @default.
• W2062655152 countsByYear W20626551522014 @default.
• W2062655152 countsByYear W20626551522016 @default.
• W2062655152 countsByYear W20626551522017 @default.
• W2062655152 countsByYear W20626551522018 @default.
• W2062655152 crossrefType "journal-article" @default.
• W2062655152 hasAuthorship W2062655152A5032254200 @default.
• W2062655152 hasAuthorship W2062655152A5035221383 @default.
• W2062655152 hasAuthorship W2062655152A5038171056 @default.
• W2062655152 hasAuthorship W2062655152A5063600149 @default.
• W2062655152 hasBestOaLocation W20626551522 @default.
• W2062655152 hasConcept C118552586 @default.
• W2062655152 hasConcept C126322002 @default.
• W2062655152 hasConcept C139719470 @default.
• W2062655152 hasConcept C142853389 @default.
• W2062655152 hasConcept C15744967 @default.
• W2062655152 hasConcept C162324750 @default.
• W2062655152 hasConcept C17923572 @default.
• W2062655152 hasConcept C2776867660 @default.
• W2062655152 hasConcept C2779177272 @default.
• W2062655152 hasConcept C44249647 @default.
• W2062655152 hasConcept C542102704 @default.
• W2062655152 hasConcept C558461103 @default.
• W2062655152 hasConcept C71924100 @default.
• W2062655152 hasConcept C77350462 @default.
• W2062655152 hasConceptScore W2062655152C118552586 @default.
• W2062655152 hasConceptScore W2062655152C126322002 @default.
• W2062655152 hasConceptScore W2062655152C139719470 @default.
• W2062655152 hasConceptScore W2062655152C142853389 @default.
• W2062655152 hasConceptScore W2062655152C15744967 @default.
• W2062655152 hasConceptScore W2062655152C162324750 @default.
• W2062655152 hasConceptScore W2062655152C17923572 @default.
• W2062655152 hasConceptScore W2062655152C2776867660 @default.
• W2062655152 hasConceptScore W2062655152C2779177272 @default.
• W2062655152 hasConceptScore W2062655152C44249647 @default.
• W2062655152 hasConceptScore W2062655152C542102704 @default.
• W2062655152 hasConceptScore W2062655152C558461103 @default.
• W2062655152 hasConceptScore W2062655152C71924100 @default.
• W2062655152 hasConceptScore W2062655152C77350462 @default.
• W2062655152 hasLocation W20626551521 @default.
• W2062655152 hasLocation W20626551522 @default.
• W2062655152 hasLocation W20626551523 @default.
• W2062655152 hasLocation W20626551524 @default.
• W2062655152 hasOpenAccess W2062655152 @default.
• W2062655152 hasPrimaryLocation W20626551521 @default.
• W2062655152 hasRelatedWork W1710805182 @default.
• W2062655152 hasRelatedWork W1857891855 @default.

• next