FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062655405> ?p ?o ?g. }

• W2062655405 endingPage "328" @default.
• W2062655405 startingPage "319" @default.
• W2062655405 abstract "The measurement of blood clotting time is important in a range of clinical applications such as assessing coagulation disorders and controlling the effect of various anticoagulant drug therapies. Clotting time tests essentially measure the onset of clot formation which results from the formation of fibrin fibers in the blood sample. However, such assays are inherently imprecise due to the highly variable nature of the clot formation process and the sample matrix. This work describes a clotting time measurement assay which uses a fluorescent probe to very precisely detect the onset of fibrin clot formation. It uses a microstructured surface which enhances the formation of multiple localized clot loci and which results in the abrupt redistribution of the fluorescent label at the onset of clot formation in both whole blood and plasma. This methodology was applied to the development of an activated partial thromboplastin time (aPTT) test in a lateral flow microfluidic platform and used to monitor the effect of heparin dosage where it showed linearity from 0 to 2 U/mL in spiked plasma samples (R2=0.996, n = 3), correlation against gold standard coagulometry of 0.9986, and correlation against standard hospital aPTT in 32 patient samples of 0.78." @default.
• W2062655405 created "2016-06-24" @default.
• W2062655405 creator A5032727757 @default.
• W2062655405 creator A5058926712 @default.
• W2062655405 creator A5060285944 @default.
• W2062655405 creator A5074284969 @default.
• W2062655405 creator A5074478702 @default.
• W2062655405 date "2010-12-01" @default.
• W2062655405 modified "2023-09-27" @default.
• W2062655405 title "Fluorescence-Based Blood Coagulation Assay Device for Measuring Activated Partial Thromboplastin Time" @default.
• W2062655405 cites W1810018036 @default.
• W2062655405 cites W1813018921 @default.
• W2062655405 cites W1988904722 @default.
• W2062655405 cites W1989940253 @default.
• W2062655405 cites W1991285364 @default.
• W2062655405 cites W1998880963 @default.
• W2062655405 cites W2000600286 @default.
• W2062655405 cites W2002635586 @default.
• W2062655405 cites W2004729908 @default.
• W2062655405 cites W2029231027 @default.
• W2062655405 cites W2031198783 @default.
• W2062655405 cites W2033198468 @default.
• W2062655405 cites W2038665865 @default.
• W2062655405 cites W2070736643 @default.
• W2062655405 cites W2082182716 @default.
• W2062655405 cites W2100646356 @default.
• W2062655405 cites W2111883975 @default.
• W2062655405 cites W2125071170 @default.
• W2062655405 cites W2129620629 @default.
• W2062655405 cites W2142389015 @default.
• W2062655405 cites W2152101805 @default.
• W2062655405 cites W2262936034 @default.
• W2062655405 cites W2326872281 @default.
• W2062655405 cites W2328155270 @default.
• W2062655405 cites W2333330110 @default.
• W2062655405 cites W2405750565 @default.
• W2062655405 cites W2412154786 @default.
• W2062655405 cites W2417381623 @default.
• W2062655405 cites W2461345642 @default.
• W2062655405 cites W4205312708 @default.
• W2062655405 cites W4245860073 @default.
• W2062655405 cites W4255367289 @default.
• W2062655405 cites W43493040 @default.
• W2062655405 doi "https://doi.org/10.1021/ac102436v" @default.
• W2062655405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21121686" @default.
• W2062655405 hasPublicationYear "2010" @default.
• W2062655405 type Work @default.
• W2062655405 sameAs 2062655405 @default.
• W2062655405 citedByCount "13" @default.
• W2062655405 countsByYear W20626554052012 @default.
• W2062655405 countsByYear W20626554052013 @default.
• W2062655405 countsByYear W20626554052016 @default.
• W2062655405 countsByYear W20626554052017 @default.
• W2062655405 countsByYear W20626554052018 @default.
• W2062655405 countsByYear W20626554052019 @default.
• W2062655405 countsByYear W20626554052020 @default.
• W2062655405 countsByYear W20626554052022 @default.
• W2062655405 crossrefType "journal-article" @default.
• W2062655405 hasAuthorship W2062655405A5032727757 @default.
• W2062655405 hasAuthorship W2062655405A5058926712 @default.
• W2062655405 hasAuthorship W2062655405A5060285944 @default.
• W2062655405 hasAuthorship W2062655405A5074284969 @default.
• W2062655405 hasAuthorship W2062655405A5074478702 @default.
• W2062655405 hasBestOaLocation W20626554052 @default.
• W2062655405 hasConcept C126322002 @default.
• W2062655405 hasConcept C136229726 @default.
• W2062655405 hasConcept C141071460 @default.
• W2062655405 hasConcept C144594695 @default.
• W2062655405 hasConcept C1621761 @default.
• W2062655405 hasConcept C185592680 @default.
• W2062655405 hasConcept C203014093 @default.
• W2062655405 hasConcept C2777557582 @default.
• W2062655405 hasConcept C2777987278 @default.
• W2062655405 hasConcept C2778205648 @default.
• W2062655405 hasConcept C2778261982 @default.
• W2062655405 hasConcept C2778382381 @default.
• W2062655405 hasConcept C2908581485 @default.
• W2062655405 hasConcept C43617362 @default.
• W2062655405 hasConcept C54173615 @default.
• W2062655405 hasConcept C55493867 @default.
• W2062655405 hasConcept C71924100 @default.
• W2062655405 hasConcept C77171857 @default.
• W2062655405 hasConcept C86803240 @default.
• W2062655405 hasConceptScore W2062655405C126322002 @default.
• W2062655405 hasConceptScore W2062655405C136229726 @default.
• W2062655405 hasConceptScore W2062655405C141071460 @default.
• W2062655405 hasConceptScore W2062655405C144594695 @default.
• W2062655405 hasConceptScore W2062655405C1621761 @default.
• W2062655405 hasConceptScore W2062655405C185592680 @default.
• W2062655405 hasConceptScore W2062655405C203014093 @default.
• W2062655405 hasConceptScore W2062655405C2777557582 @default.
• W2062655405 hasConceptScore W2062655405C2777987278 @default.
• W2062655405 hasConceptScore W2062655405C2778205648 @default.
• W2062655405 hasConceptScore W2062655405C2778261982 @default.
• W2062655405 hasConceptScore W2062655405C2778382381 @default.
• W2062655405 hasConceptScore W2062655405C2908581485 @default.
• W2062655405 hasConceptScore W2062655405C43617362 @default.
• W2062655405 hasConceptScore W2062655405C54173615 @default.

• next