FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062661013> ?p ?o ?g. }

• W2062661013 endingPage "7731" @default.
• W2062661013 startingPage "7724" @default.
• W2062661013 abstract "Widespread applications of conventional polymeric gene carriers are greatly hampered by their inefficient transfection performance under serum-containing environment. Aiming to overcome this limitation, we propose a bioreducible polyethylenimine-gold nanocomplex system (SSPEI-Au NC), which can be prepared by a simple layer-by-layer (LBL) assembly procedure. SSPEI-Au NC contains sequentially deposited layers of bioreducible polyethylenimine (SSPEI) and poly(γ-glutamic acid) (γ-PGA) for efficient binding and delivery of plasmid DNA (pDNA). SSPEI-Au NC was characterized for various physicochemical properties, including: UV-vis spectra, TEM imaging, hydrodynamic size, and pDNA binding ability. The SSPEI-Au NC were efficiently uptaken by mammalian cells as observed using dark-field microscopy. Comparing to nondegradable PEI25k, the bioreducible SSPEI-Au NC exhibited superior transfection capability under serum-containing condition while causing lower cytotoxicity on mammalian cell lines. The effect of serum on SSPEI-Au NC dispersity was studied using UV-vis spectrometry and the results suggest that serum-assisted colloidal stability of SSPEI-Au NC contributed to its serum-resistant transfection." @default.
• W2062661013 created "2016-06-24" @default.
• W2062661013 creator A5048286805 @default.
• W2062661013 creator A5064913310 @default.
• W2062661013 date "2015-03-20" @default.
• W2062661013 modified "2023-10-13" @default.
• W2062661013 title "Complexation of Bioreducible Cationic Polymers with Gold Nanoparticles for Improving Stability in Serum and Application on Nonviral Gene Delivery" @default.
• W2062661013 cites W1965866951 @default.
• W2062661013 cites W1972775797 @default.
• W2062661013 cites W1980352701 @default.
• W2062661013 cites W1981439401 @default.
• W2062661013 cites W1982629566 @default.
• W2062661013 cites W1986307528 @default.
• W2062661013 cites W2001031612 @default.
• W2062661013 cites W2001218002 @default.
• W2062661013 cites W2006645179 @default.
• W2062661013 cites W2015755230 @default.
• W2062661013 cites W2016097990 @default.
• W2062661013 cites W2033711847 @default.
• W2062661013 cites W2038969379 @default.
• W2062661013 cites W2050432620 @default.
• W2062661013 cites W2051799869 @default.
• W2062661013 cites W2055721190 @default.
• W2062661013 cites W2056560999 @default.
• W2062661013 cites W2058552215 @default.
• W2062661013 cites W2075585703 @default.
• W2062661013 cites W2085380241 @default.
• W2062661013 cites W2087403976 @default.
• W2062661013 cites W2103912663 @default.
• W2062661013 cites W2111602311 @default.
• W2062661013 cites W2117161686 @default.
• W2062661013 cites W2120692644 @default.
• W2062661013 cites W2166479549 @default.
• W2062661013 cites W2314516700 @default.
• W2062661013 cites W2323270466 @default.
• W2062661013 cites W2327935215 @default.
• W2062661013 cites W3023288964 @default.
• W2062661013 doi "https://doi.org/10.1021/acsami.5b00732" @default.
• W2062661013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25764067" @default.
• W2062661013 hasPublicationYear "2015" @default.
• W2062661013 type Work @default.
• W2062661013 sameAs 2062661013 @default.
• W2062661013 citedByCount "22" @default.
• W2062661013 countsByYear W20626610132015 @default.
• W2062661013 countsByYear W20626610132016 @default.
• W2062661013 countsByYear W20626610132017 @default.
• W2062661013 countsByYear W20626610132018 @default.
• W2062661013 countsByYear W20626610132019 @default.
• W2062661013 countsByYear W20626610132020 @default.
• W2062661013 countsByYear W20626610132021 @default.
• W2062661013 countsByYear W20626610132022 @default.
• W2062661013 countsByYear W20626610132023 @default.
• W2062661013 crossrefType "journal-article" @default.
• W2062661013 hasAuthorship W2062661013A5048286805 @default.
• W2062661013 hasAuthorship W2062661013A5064913310 @default.
• W2062661013 hasConcept C104317684 @default.
• W2062661013 hasConcept C109316439 @default.
• W2062661013 hasConcept C11432220 @default.
• W2062661013 hasConcept C12554922 @default.
• W2062661013 hasConcept C135983454 @default.
• W2062661013 hasConcept C153356533 @default.
• W2062661013 hasConcept C155672457 @default.
• W2062661013 hasConcept C159985019 @default.
• W2062661013 hasConcept C171250308 @default.
• W2062661013 hasConcept C183882617 @default.
• W2062661013 hasConcept C185592680 @default.
• W2062661013 hasConcept C188027245 @default.
• W2062661013 hasConcept C192562407 @default.
• W2062661013 hasConcept C202751555 @default.
• W2062661013 hasConcept C204389451 @default.
• W2062661013 hasConcept C2775925850 @default.
• W2062661013 hasConcept C521977710 @default.
• W2062661013 hasConcept C54009773 @default.
• W2062661013 hasConcept C55493867 @default.
• W2062661013 hasConcept C86181022 @default.
• W2062661013 hasConcept C86803240 @default.
• W2062661013 hasConceptScore W2062661013C104317684 @default.
• W2062661013 hasConceptScore W2062661013C109316439 @default.
• W2062661013 hasConceptScore W2062661013C11432220 @default.
• W2062661013 hasConceptScore W2062661013C12554922 @default.
• W2062661013 hasConceptScore W2062661013C135983454 @default.
• W2062661013 hasConceptScore W2062661013C153356533 @default.
• W2062661013 hasConceptScore W2062661013C155672457 @default.
• W2062661013 hasConceptScore W2062661013C159985019 @default.
• W2062661013 hasConceptScore W2062661013C171250308 @default.
• W2062661013 hasConceptScore W2062661013C183882617 @default.
• W2062661013 hasConceptScore W2062661013C185592680 @default.
• W2062661013 hasConceptScore W2062661013C188027245 @default.
• W2062661013 hasConceptScore W2062661013C192562407 @default.
• W2062661013 hasConceptScore W2062661013C202751555 @default.
• W2062661013 hasConceptScore W2062661013C204389451 @default.
• W2062661013 hasConceptScore W2062661013C2775925850 @default.
• W2062661013 hasConceptScore W2062661013C521977710 @default.
• W2062661013 hasConceptScore W2062661013C54009773 @default.
• W2062661013 hasConceptScore W2062661013C55493867 @default.
• W2062661013 hasConceptScore W2062661013C86181022 @default.
• W2062661013 hasConceptScore W2062661013C86803240 @default.
• W2062661013 hasFunder F4320321040 @default.

• next