FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062672912> ?p ?o ?g. }

• W2062672912 endingPage "513" @default.
• W2062672912 startingPage "503" @default.
• W2062672912 abstract "Epithelial cells mostly orient the spindle along the plane of the epithelium (planar orientation) for mitosis to produce two identical daughter cells. The correct orientation of the spindle relies on the interaction between cortical polarity components and astral microtubules. Recent studies in mammalian tissue culture cells suggest that the apically localised atypical protein kinase C (aPKC) is important for the planar orientation of the mitotic spindle in dividing epithelial cells. Yet, in chicken neuroepithelial cells, aPKC is not required in vivo for spindle orientation, and it has been proposed that the polarization cues vary between different epithelial cell types and/or developmental processes. In order to investigate whether Drosophila aPKC is required for spindle orientation during symmetric division of epithelial cells, we took advantage of a previously isolated temperature-sensitive allele of aPKC. We showed that Drosophila aPKC is required in vivo for spindle planar orientation and apical exclusion of Pins (Raps). This suggests that the cortical cues necessary for spindle orientation are not only conserved between Drosophila and mammalian cells, but are also similar to those required for spindle apicobasal orientation during asymmetric cell division." @default.
• W2062672912 created "2016-06-24" @default.
• W2062672912 creator A5029624631 @default.
• W2062672912 creator A5049901408 @default.
• W2062672912 creator A5063635149 @default.
• W2062672912 creator A5064385054 @default.
• W2062672912 creator A5070271391 @default.
• W2062672912 date "2012-02-01" @default.
• W2062672912 modified "2023-10-01" @default.
• W2062672912 title "<i>Drosophila</i> aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells" @default.
• W2062672912 cites W1502837338 @default.
• W2062672912 cites W1560056935 @default.
• W2062672912 cites W1573053105 @default.
• W2062672912 cites W1595817144 @default.
• W2062672912 cites W1984024996 @default.
• W2062672912 cites W1990188178 @default.
• W2062672912 cites W1994404140 @default.
• W2062672912 cites W2002315827 @default.
• W2062672912 cites W2003067279 @default.
• W2062672912 cites W2027235566 @default.
• W2062672912 cites W2028511117 @default.
• W2062672912 cites W2028945975 @default.
• W2062672912 cites W2029572691 @default.
• W2062672912 cites W2034696312 @default.
• W2062672912 cites W2036355011 @default.
• W2062672912 cites W2036833378 @default.
• W2062672912 cites W2045843159 @default.
• W2062672912 cites W2048039677 @default.
• W2062672912 cites W2051221246 @default.
• W2062672912 cites W2058036227 @default.
• W2062672912 cites W2059400753 @default.
• W2062672912 cites W2063197874 @default.
• W2062672912 cites W2082074319 @default.
• W2062672912 cites W2084808179 @default.
• W2062672912 cites W2084887960 @default.
• W2062672912 cites W2089839677 @default.
• W2062672912 cites W2090700126 @default.
• W2062672912 cites W2097125495 @default.
• W2062672912 cites W2099378655 @default.
• W2062672912 cites W2100143950 @default.
• W2062672912 cites W2114786488 @default.
• W2062672912 cites W2125031377 @default.
• W2062672912 cites W2126070753 @default.
• W2062672912 cites W2136872433 @default.
• W2062672912 cites W2141251844 @default.
• W2062672912 cites W2143057291 @default.
• W2062672912 cites W2146015448 @default.
• W2062672912 cites W2147819429 @default.
• W2062672912 cites W2161930851 @default.
• W2062672912 cites W2163043134 @default.
• W2062672912 cites W2168436318 @default.
• W2062672912 cites W2168826080 @default.
• W2062672912 doi "https://doi.org/10.1242/dev.071027" @default.
• W2062672912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22223679" @default.
• W2062672912 hasPublicationYear "2012" @default.
• W2062672912 type Work @default.
• W2062672912 sameAs 2062672912 @default.
• W2062672912 citedByCount "56" @default.
• W2062672912 countsByYear W20626729122012 @default.
• W2062672912 countsByYear W20626729122013 @default.
• W2062672912 countsByYear W20626729122014 @default.
• W2062672912 countsByYear W20626729122015 @default.
• W2062672912 countsByYear W20626729122016 @default.
• W2062672912 countsByYear W20626729122017 @default.
• W2062672912 countsByYear W20626729122018 @default.
• W2062672912 countsByYear W20626729122019 @default.
• W2062672912 countsByYear W20626729122020 @default.
• W2062672912 countsByYear W20626729122021 @default.
• W2062672912 countsByYear W20626729122022 @default.
• W2062672912 crossrefType "journal-article" @default.
• W2062672912 hasAuthorship W2062672912A5029624631 @default.
• W2062672912 hasAuthorship W2062672912A5049901408 @default.
• W2062672912 hasAuthorship W2062672912A5063635149 @default.
• W2062672912 hasAuthorship W2062672912A5064385054 @default.
• W2062672912 hasAuthorship W2062672912A5070271391 @default.
• W2062672912 hasBestOaLocation W20626729121 @default.
• W2062672912 hasConcept C1491633281 @default.
• W2062672912 hasConcept C20418707 @default.
• W2062672912 hasConcept C2778977658 @default.
• W2062672912 hasConcept C29537977 @default.
• W2062672912 hasConcept C47432576 @default.
• W2062672912 hasConcept C49353375 @default.
• W2062672912 hasConcept C54355233 @default.
• W2062672912 hasConcept C70547292 @default.
• W2062672912 hasConcept C84815855 @default.
• W2062672912 hasConcept C85813293 @default.
• W2062672912 hasConcept C86803240 @default.
• W2062672912 hasConcept C93304396 @default.
• W2062672912 hasConcept C95444343 @default.
• W2062672912 hasConcept C9565192 @default.
• W2062672912 hasConceptScore W2062672912C1491633281 @default.
• W2062672912 hasConceptScore W2062672912C20418707 @default.
• W2062672912 hasConceptScore W2062672912C2778977658 @default.
• W2062672912 hasConceptScore W2062672912C29537977 @default.
• W2062672912 hasConceptScore W2062672912C47432576 @default.
• W2062672912 hasConceptScore W2062672912C49353375 @default.
• W2062672912 hasConceptScore W2062672912C54355233 @default.
• W2062672912 hasConceptScore W2062672912C70547292 @default.

• next