FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062699548> ?p ?o ?g. }

• W2062699548 endingPage "84" @default.
• W2062699548 startingPage "82" @default.
• W2062699548 abstract "Acute myelogenous leukemia has been associated with several recurrent genetic abnormalities, each with specific prognostic implications [ [1] Kolomietz E. Al-Maghrabi J. Brennan S. Karaskova J. Minkin S. Lipton J. Squire J.A. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis. Blood. 2001; 97: 3581-3588 Crossref PubMed Scopus (192) Google Scholar ]. Acute myelomonocytic leukemia with eosinophilia (FAB classification AML M4 Eo) is characterized by monocytic and granulocytic differentiation with a prominent eosinophilic component. AML M4 Eo is commonly associated with pericentric inversions of chromosome 16, involving the core binding factor beta gene (CBFB) on 16q22 and the myosin heavy chain gene (MYH11) on 16p13 [ 2 Le Beau M.M. Larson R.A. Bitter M.A. Vardiman J.W. Golomb H.M. Rowley J.D. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia: a unique cytogenetic–clinicopathological association. N Engl J Med. 1983; 309: 630-636 Crossref PubMed Scopus (445) Google Scholar , 3 Liu P. Tarlé S.A. Hajra A. Claxton D.F. Marlton P. Freedman M. Siciliano M.J. Collins F.S. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Science. 1993; 261: 1041-1044 Crossref PubMed Scopus (655) Google Scholar ]. Inversion of chromosome 16 creates a fusion gene composed of the 5′ CBFB gene and the 3′ MYH11 gene on the short arm of the inverted chromosome [ [3] Liu P. Tarlé S.A. Hajra A. Claxton D.F. Marlton P. Freedman M. Siciliano M.J. Collins F.S. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Science. 1993; 261: 1041-1044 Crossref PubMed Scopus (655) Google Scholar ]. This fusion gene interferes with the normal transcriptional activity of the CBFA/CBFB heterodimer, and disrupts transcription of genes necessary for myeloid differentiation. The inversion inv(16)(p13q22) is considered a favorable prognostic indicator; with current chemotherapy regimens that incorporate high-dose cytarabine, patients with this chromosomal aberration tend to do better than other patients with AML [ 4 Bloomfield C.D. Shuma C. Regal L. Philip P.P. Hossfeld D.K. Hagemeijer A.M. Garson O.M. Peterson B.A. Sakurai M. Alimena G. Berger R. Rowley J.D. Ruutu T. Mitelman F. Dewald G.W. Swansbury J. Long-term survival of patients with acute myeloid leukemia: a third follow-up of the Fourth International Workshop on Chromosomes in Leukemia. Cancer. 1997; 80: 2191-2198 Crossref PubMed Google Scholar , 5 Delaunay J. Vey N. Leblanc T. Fenaux P. Rigal-Huguet F. Witz F. Lamy T. Auvrignon A. Blaise D. Pigneux A. Mugneret F. Bastard C. Dastugue N. Van den Akker J. Fiere D. Reiffers J. Castaigne S. Leverger G. Harousseau J.L. Dombret H. French Acute Myeloid Leukemia Intergroup; Groupe Ouest-Est des Leucémies Aigües Myeoblastiques; Leucémies Aigües Myeoblastiques de l'Enfant; Acute Leukemia French Association; Bordeaux-Grenoble-Marseille-Toulouse cooperative groups. Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup. Blood. 2003; 102: 462-469 Crossref PubMed Scopus (162) Google Scholar ]." @default.
• W2062699548 created "2016-06-24" @default.
• W2062699548 creator A5049350161 @default.
• W2062699548 creator A5053690777 @default.
• W2062699548 creator A5076974313 @default.
• W2062699548 creator A5087767536 @default.
• W2062699548 date "2007-11-01" @default.
• W2062699548 modified "2023-09-27" @default.
• W2062699548 title "Inverted and deleted chromosome 16 with deletion of 3′ CBFB identified by fluorescence in situ hybridization" @default.
• W2062699548 cites W1965569038 @default.
• W2062699548 cites W1985368637 @default.
• W2062699548 cites W2047591593 @default.
• W2062699548 cites W2054037962 @default.
• W2062699548 cites W2077954350 @default.
• W2062699548 cites W2079004059 @default.
• W2062699548 cites W2123081362 @default.
• W2062699548 cites W2127016965 @default.
• W2062699548 cites W2328556759 @default.
• W2062699548 cites W76376182 @default.
• W2062699548 doi "https://doi.org/10.1016/j.cancergencyto.2007.08.007" @default.
• W2062699548 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17981221" @default.
• W2062699548 hasPublicationYear "2007" @default.
• W2062699548 type Work @default.
• W2062699548 sameAs 2062699548 @default.
• W2062699548 citedByCount "4" @default.
• W2062699548 countsByYear W20626995482020 @default.
• W2062699548 countsByYear W20626995482022 @default.
• W2062699548 crossrefType "journal-article" @default.
• W2062699548 hasAuthorship W2062699548A5049350161 @default.
• W2062699548 hasAuthorship W2062699548A5053690777 @default.
• W2062699548 hasAuthorship W2062699548A5076974313 @default.
• W2062699548 hasAuthorship W2062699548A5087767536 @default.
• W2062699548 hasConcept C104317684 @default.
• W2062699548 hasConcept C111829193 @default.
• W2062699548 hasConcept C153911025 @default.
• W2062699548 hasConcept C165984737 @default.
• W2062699548 hasConcept C2777542201 @default.
• W2062699548 hasConcept C30481170 @default.
• W2062699548 hasConcept C53226629 @default.
• W2062699548 hasConcept C54355233 @default.
• W2062699548 hasConcept C86803240 @default.
• W2062699548 hasConceptScore W2062699548C104317684 @default.
• W2062699548 hasConceptScore W2062699548C111829193 @default.
• W2062699548 hasConceptScore W2062699548C153911025 @default.
• W2062699548 hasConceptScore W2062699548C165984737 @default.
• W2062699548 hasConceptScore W2062699548C2777542201 @default.
• W2062699548 hasConceptScore W2062699548C30481170 @default.
• W2062699548 hasConceptScore W2062699548C53226629 @default.
• W2062699548 hasConceptScore W2062699548C54355233 @default.
• W2062699548 hasConceptScore W2062699548C86803240 @default.
• W2062699548 hasIssue "1" @default.
• W2062699548 hasLocation W20626995481 @default.
• W2062699548 hasLocation W20626995482 @default.
• W2062699548 hasOpenAccess W2062699548 @default.
• W2062699548 hasPrimaryLocation W20626995481 @default.
• W2062699548 hasRelatedWork W1970446973 @default.
• W2062699548 hasRelatedWork W1987287319 @default.
• W2062699548 hasRelatedWork W2001519584 @default.
• W2062699548 hasRelatedWork W2031436818 @default.
• W2062699548 hasRelatedWork W2036374520 @default.
• W2062699548 hasRelatedWork W2128111640 @default.
• W2062699548 hasRelatedWork W2145816365 @default.
• W2062699548 hasRelatedWork W2355121570 @default.
• W2062699548 hasRelatedWork W2367579304 @default.
• W2062699548 hasRelatedWork W3024939118 @default.
• W2062699548 hasVolume "179" @default.
• W2062699548 isParatext "false" @default.
• W2062699548 isRetracted "false" @default.
• W2062699548 magId "2062699548" @default.
• W2062699548 workType "article" @default.