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• W2062720002 abstract "Purpose: Because of its rarity in any oncology centre, the clinical trends of male breast cancer specific to its geographical distribution have remained relatively unexplored. This study was done to analyze the clinico-pathological data, treatment given and survival patterns of male breast cancer patients visiting our tertiary medical centre and compare our results with available literature. Methods : All male breast cancer patients registered at our clinic from 2003 to 2009 were included. Frequency distribution analysis of the demographic and clinico-pathological data and treatment variables was done. Treatment outcome was examined from Kaplan-Meir survival estimates. Results: Thirty-three male breast cancer patients were encountered. The median age of presentation was sixty years. Mostly (87.9%) they presented with lump in breast or axilla and were clinically staged to be ‘3’ (57.6%).Obesity and alcohol were the commonest risk factors identified. Modified radical mastectomy was the commonest (69.6%) definitive therapy rendered with (only for clinically staged 3 patients) or without neo-adjuvant chemotherapy. Infiltrating ductal carcinoma was identified in most cases. Twenty-two patients received adjuvant chemotherapy and twenty-four received adjuvant radiotherapy. Eighteen (54.5%) patients were hormone-receptor positive and received tamoxifen. The median Overall survival (OS) and Progression-free survival (PFS) came out to be 14.3 months (standard error, SE of 1.185; 95% confidence interval, CI 12-16.6) and 15.7 (SE 5.35, 95% CI 5.2-26.19) months respectively. Conclusion : Male breast cancers usually carry a poor prognosis due to presentation at later stages. Most of our results correlate with previous literature. Multi-centric prospective studies are required to validate the etiological factors and prognostic determinants of survival. ----------------------------- Cite this article as: Mukherjee A, Saha A, Chattopadhyay S, Sur P. Clinical trends and outcomes of Male Breast Cancer: experience of a tertiary oncology centre in India. Int J Cancer Ther Oncol 2014; 2 (3):02035. DOI : 10.14319/ijcto.0203.5" @default.
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• W2062720002 date "2014-05-22" @default.
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• W2062720002 title "Clinical trends and outcomes of male breast cancer: Experience of a tertiary oncology centre in India" @default.
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• W2062720002 doi "https://doi.org/10.14319/ijcto.0203.5" @default.
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