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• W2062730953 endingPage "1106" @default.
• W2062730953 startingPage "1096" @default.
• W2062730953 abstract "The aim of this study was to investigate the short-term effects of tertiary-treated municipal effluents on the freshwater mussel Elliptio complanata. Caged mussels were immersed during 2 weeks in a river located North of Montreal Island, upstream/downstream the outfall and in one reference site located at the beginning of the Rivière des Prairies. A selection of biomarkers was analyzed to depict changes on various physiological systems: general physiology (mussel viability, condition index and gonado-somatic index), immune status (hemocyte viability, cellularity, phagocytosis efficiency, NK-like cytotoxic activity and lysozyme activity), inflammation (cyclo-oxygenase activity), detoxification (glutathione-S-transferases activity) and vitellogenesis (alkali-labile phosphate level). The analysis of total and fecal coliform counts in water and of heterotrophic bacteria levels in mussel tissues showed that the bacteriological quality of the water strongly decreased from the reference site to the downstream site. This was correlated with a significant loss of weight and an increase of mussel mortality. Cellularity and phagocytosis efficiency were significantly increased in the downstream site compared to the reference site. Though not statistically significant, lysozyme activity was also increased. NK-like cytotoxicity, activity of the pro-inflammatory enzyme COX and the levels of ALP and MT were not significantly changed. Conversely, the municipal effluents induced a significant increase of GST activity in downstream site, indicating a stimulation of detoxification metabolism. Altogether, these results confirm that a short-term exposure to a mixture of bacterial and chemical compounds released by the wastewater treatment plant La Pinière induces adverse physiological effects in E. complanata, as observed with the modulation of immune response and induction of detoxification metabolism." @default.
• W2062730953 created "2016-06-24" @default.
• W2062730953 creator A5006270431 @default.
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• W2062730953 date "2011-11-01" @default.
• W2062730953 modified "2023-09-28" @default.
• W2062730953 title "Short-term physiological effects of a xenobiotic mixture on the freshwater mussel Elliptio complanata exposed to municipal effluents" @default.
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• W2062730953 doi "https://doi.org/10.1016/j.envres.2011.07.009" @default.
• W2062730953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21831370" @default.
• W2062730953 hasPublicationYear "2011" @default.

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