Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062739582> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2062739582 endingPage "9361" @default.
- W2062739582 startingPage "9354" @default.
- W2062739582 abstract "A remarkable recent discovery in red blood cell function is that the Rhesus antigen complex that for so long was considered to be simply a means of cell recognition is also the ammonia transporter. It catalyzes transmembrane exchange of ammonia on the subsecond time scale, and yet because of a lack of rapid-exchange methodology its kinetics had not been characterized. The flux of ammonia varies appreciably in diverse clinical states, and a convenient method for its characterization would be of basic and of clinical diagnostic value. Fluoroethylamine is water-soluble and when added to a suspension of human red blood cells (RBCs) displays the experimentally useful property of giving separate 19F NMR spectral peaks for the populations inside and outside the cells. By using two-site, one-dimensional magnetization exchange spectroscopy (1D-EXSY), the transmembrane exchange of fluoroethylamine was measured; it was found to occur on the subsecond time scale with an apparent first-order rate constant for efflux, under the equilibrium exchange conditions, of 3.4 s(-1). The method was used to characterize the concentration, temperature, and pH dependence of the exchange rate constant. We determined the extent of competitive inhibition exhibited by ammonia and two molecules that contain an amine group (ethylamine and methylamine). Inhibition of the exchange by incubating the suspension with anti-RhAG antibody, and no inhibition by anti-RhD antibody, suggested specificity of exchange via the RhAG protein of the Rh complex." @default.
- W2062739582 created "2016-06-24" @default.
- W2062739582 creator A5002951013 @default.
- W2062739582 creator A5037543636 @default.
- W2062739582 creator A5053932606 @default.
- W2062739582 creator A5081563103 @default.
- W2062739582 date "2006-07-07" @default.
- W2062739582 modified "2023-09-24" @default.
- W2062739582 title "Rapid Exchange of Fluoroethylamine via the Rhesus Complex in Human Erythrocytes: <sup>19</sup>F NMR Magnetization Transfer Analysis Showing Competition by Ammonia and Ammonia Analogues" @default.
- W2062739582 cites W1562801779 @default.
- W2062739582 cites W1578413957 @default.
- W2062739582 cites W1877828639 @default.
- W2062739582 cites W1926579911 @default.
- W2062739582 cites W2025348885 @default.
- W2062739582 cites W2052422985 @default.
- W2062739582 cites W2059179751 @default.
- W2062739582 cites W2317164129 @default.
- W2062739582 cites W2333767572 @default.
- W2062739582 cites W4206550032 @default.
- W2062739582 doi "https://doi.org/10.1021/bi060505n" @default.
- W2062739582 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16866382" @default.
- W2062739582 hasPublicationYear "2006" @default.
- W2062739582 type Work @default.
- W2062739582 sameAs 2062739582 @default.
- W2062739582 citedByCount "9" @default.
- W2062739582 countsByYear W20627395822016 @default.
- W2062739582 countsByYear W20627395822017 @default.
- W2062739582 countsByYear W20627395822018 @default.
- W2062739582 countsByYear W20627395822019 @default.
- W2062739582 crossrefType "journal-article" @default.
- W2062739582 hasAuthorship W2062739582A5002951013 @default.
- W2062739582 hasAuthorship W2062739582A5037543636 @default.
- W2062739582 hasAuthorship W2062739582A5053932606 @default.
- W2062739582 hasAuthorship W2062739582A5081563103 @default.
- W2062739582 hasConcept C121332964 @default.
- W2062739582 hasConcept C12554922 @default.
- W2062739582 hasConcept C126838900 @default.
- W2062739582 hasConcept C143409427 @default.
- W2062739582 hasConcept C144647389 @default.
- W2062739582 hasConcept C147789679 @default.
- W2062739582 hasConcept C148898269 @default.
- W2062739582 hasConcept C185592680 @default.
- W2062739582 hasConcept C2776382133 @default.
- W2062739582 hasConcept C2776557347 @default.
- W2062739582 hasConcept C2776589458 @default.
- W2062739582 hasConcept C2778678469 @default.
- W2062739582 hasConcept C2778969155 @default.
- W2062739582 hasConcept C27826641 @default.
- W2062739582 hasConcept C41625074 @default.
- W2062739582 hasConcept C55493867 @default.
- W2062739582 hasConcept C62520636 @default.
- W2062739582 hasConcept C71240020 @default.
- W2062739582 hasConcept C71924100 @default.
- W2062739582 hasConcept C86803240 @default.
- W2062739582 hasConcept C93391505 @default.
- W2062739582 hasConceptScore W2062739582C121332964 @default.
- W2062739582 hasConceptScore W2062739582C12554922 @default.
- W2062739582 hasConceptScore W2062739582C126838900 @default.
- W2062739582 hasConceptScore W2062739582C143409427 @default.
- W2062739582 hasConceptScore W2062739582C144647389 @default.
- W2062739582 hasConceptScore W2062739582C147789679 @default.
- W2062739582 hasConceptScore W2062739582C148898269 @default.
- W2062739582 hasConceptScore W2062739582C185592680 @default.
- W2062739582 hasConceptScore W2062739582C2776382133 @default.
- W2062739582 hasConceptScore W2062739582C2776557347 @default.
- W2062739582 hasConceptScore W2062739582C2776589458 @default.
- W2062739582 hasConceptScore W2062739582C2778678469 @default.
- W2062739582 hasConceptScore W2062739582C2778969155 @default.
- W2062739582 hasConceptScore W2062739582C27826641 @default.
- W2062739582 hasConceptScore W2062739582C41625074 @default.
- W2062739582 hasConceptScore W2062739582C55493867 @default.
- W2062739582 hasConceptScore W2062739582C62520636 @default.
- W2062739582 hasConceptScore W2062739582C71240020 @default.
- W2062739582 hasConceptScore W2062739582C71924100 @default.
- W2062739582 hasConceptScore W2062739582C86803240 @default.
- W2062739582 hasConceptScore W2062739582C93391505 @default.
- W2062739582 hasIssue "30" @default.
- W2062739582 hasLocation W20627395821 @default.
- W2062739582 hasLocation W20627395822 @default.
- W2062739582 hasOpenAccess W2062739582 @default.
- W2062739582 hasPrimaryLocation W20627395821 @default.
- W2062739582 hasRelatedWork W1556319456 @default.
- W2062739582 hasRelatedWork W1971006064 @default.
- W2062739582 hasRelatedWork W2036428514 @default.
- W2062739582 hasRelatedWork W2046802915 @default.
- W2062739582 hasRelatedWork W2052780656 @default.
- W2062739582 hasRelatedWork W2064011811 @default.
- W2062739582 hasRelatedWork W2095954763 @default.
- W2062739582 hasRelatedWork W2135755331 @default.
- W2062739582 hasRelatedWork W228662401 @default.
- W2062739582 hasRelatedWork W2904857710 @default.
- W2062739582 hasVolume "45" @default.
- W2062739582 isParatext "false" @default.
- W2062739582 isRetracted "false" @default.
- W2062739582 magId "2062739582" @default.
- W2062739582 workType "article" @default.