FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062817549> ?p ?o ?g. }

• W2062817549 endingPage "218" @default.
• W2062817549 startingPage "213" @default.
• W2062817549 abstract "We developed an in vitro screening system for antihyperlipidemic activity by measuring lipoprotein profiles secreted from human intestinal epithelium-like cells from the colon cancer cell line, Caco-2. Sodium (Na) butyrate at 5 mM differentiated Caco-2 cells into intestinal epithelium-like cells and numerous microvilli on the apical side of cells were observed under transmission electron microscopy. Real-time RT-PCR analysis revealed that Na butyrate stimulated expression levels of intestinal differentiation markers in Caco-2 cells in a dose-dependent manner and 5 mM Na butyrate up-regulated intestinal alkaline phosphatase, sucrase–isomaltase complex, and microsomal triglyceride transfer protein by 8.1-, 1.9-, and 2.1-fold that of non-treated cells, respectively. Lipoprotein secretions from differentiated Caco-2 cells were promoted by lysophosphatidyl choline and Na oleate, which are a stimulator of lipoprotein secretion and a substrate of triglycerides, respectively. We examined the effects of Pluronic L-81, a lipoprotein secretion inhibitor, on lipoprotein profiles of differentiated Caco-2 cells. Pluronic L-81 at 1.0 μg/ml inhibited TG contents in lipoprotein fractions from cells by 25.6 % and secretion was completely suppressed by the agent at 10 μg/ml." @default.
• W2062817549 created "2016-06-24" @default.
• W2062817549 creator A5000851112 @default.
• W2062817549 creator A5026321214 @default.
• W2062817549 creator A5033209408 @default.
• W2062817549 creator A5039795050 @default.
• W2062817549 creator A5056498978 @default.
• W2062817549 creator A5067636810 @default.
• W2062817549 creator A5069516350 @default.
• W2062817549 creator A5070627622 @default.
• W2062817549 creator A5086136301 @default.
• W2062817549 date "2012-09-05" @default.
• W2062817549 modified "2023-10-05" @default.
• W2062817549 title "An in vitro assay system for antihyperlipidemic agents by evaluating lipoprotein profiles from human intestinal epithelium-like cells" @default.
• W2062817549 cites W1874699653 @default.
• W2062817549 cites W1948504907 @default.
• W2062817549 cites W1972580189 @default.
• W2062817549 cites W2000899073 @default.
• W2062817549 cites W2033770158 @default.
• W2062817549 cites W2046320133 @default.
• W2062817549 cites W2066342412 @default.
• W2062817549 cites W2075131415 @default.
• W2062817549 cites W2108306194 @default.
• W2062817549 cites W2108997457 @default.
• W2062817549 cites W2116361358 @default.
• W2062817549 cites W2131675835 @default.
• W2062817549 cites W2140510507 @default.
• W2062817549 cites W2151400756 @default.
• W2062817549 cites W2157030222 @default.
• W2062817549 doi "https://doi.org/10.1007/s13205-012-0085-1" @default.
• W2062817549 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3646105" @default.
• W2062817549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28324370" @default.
• W2062817549 hasPublicationYear "2012" @default.
• W2062817549 type Work @default.
• W2062817549 sameAs 2062817549 @default.
• W2062817549 citedByCount "2" @default.
• W2062817549 countsByYear W20628175492017 @default.
• W2062817549 countsByYear W20628175492019 @default.
• W2062817549 crossrefType "journal-article" @default.
• W2062817549 hasAuthorship W2062817549A5000851112 @default.
• W2062817549 hasAuthorship W2062817549A5026321214 @default.
• W2062817549 hasAuthorship W2062817549A5033209408 @default.
• W2062817549 hasAuthorship W2062817549A5039795050 @default.
• W2062817549 hasAuthorship W2062817549A5056498978 @default.
• W2062817549 hasAuthorship W2062817549A5067636810 @default.
• W2062817549 hasAuthorship W2062817549A5069516350 @default.
• W2062817549 hasAuthorship W2062817549A5070627622 @default.
• W2062817549 hasAuthorship W2062817549A5086136301 @default.
• W2062817549 hasBestOaLocation W20628175492 @default.
• W2062817549 hasConcept C100544194 @default.
• W2062817549 hasConcept C104317684 @default.
• W2062817549 hasConcept C134018914 @default.
• W2062817549 hasConcept C153911025 @default.
• W2062817549 hasConcept C160160445 @default.
• W2062817549 hasConcept C181199279 @default.
• W2062817549 hasConcept C185592680 @default.
• W2062817549 hasConcept C193176779 @default.
• W2062817549 hasConcept C202751555 @default.
• W2062817549 hasConcept C2776979534 @default.
• W2062817549 hasConcept C2778163477 @default.
• W2062817549 hasConcept C2778942008 @default.
• W2062817549 hasConcept C2780072125 @default.
• W2062817549 hasConcept C2781077229 @default.
• W2062817549 hasConcept C49039625 @default.
• W2062817549 hasConcept C529295009 @default.
• W2062817549 hasConcept C54355233 @default.
• W2062817549 hasConcept C55493867 @default.
• W2062817549 hasConcept C81885089 @default.
• W2062817549 hasConcept C86803240 @default.
• W2062817549 hasConceptScore W2062817549C100544194 @default.
• W2062817549 hasConceptScore W2062817549C104317684 @default.
• W2062817549 hasConceptScore W2062817549C134018914 @default.
• W2062817549 hasConceptScore W2062817549C153911025 @default.
• W2062817549 hasConceptScore W2062817549C160160445 @default.
• W2062817549 hasConceptScore W2062817549C181199279 @default.
• W2062817549 hasConceptScore W2062817549C185592680 @default.
• W2062817549 hasConceptScore W2062817549C193176779 @default.
• W2062817549 hasConceptScore W2062817549C202751555 @default.
• W2062817549 hasConceptScore W2062817549C2776979534 @default.
• W2062817549 hasConceptScore W2062817549C2778163477 @default.
• W2062817549 hasConceptScore W2062817549C2778942008 @default.
• W2062817549 hasConceptScore W2062817549C2780072125 @default.
• W2062817549 hasConceptScore W2062817549C2781077229 @default.
• W2062817549 hasConceptScore W2062817549C49039625 @default.
• W2062817549 hasConceptScore W2062817549C529295009 @default.
• W2062817549 hasConceptScore W2062817549C54355233 @default.
• W2062817549 hasConceptScore W2062817549C55493867 @default.
• W2062817549 hasConceptScore W2062817549C81885089 @default.
• W2062817549 hasConceptScore W2062817549C86803240 @default.
• W2062817549 hasIssue "3" @default.
• W2062817549 hasLocation W20628175491 @default.
• W2062817549 hasLocation W20628175492 @default.
• W2062817549 hasLocation W20628175493 @default.
• W2062817549 hasOpenAccess W2062817549 @default.
• W2062817549 hasPrimaryLocation W20628175491 @default.
• W2062817549 hasRelatedWork W1571122109 @default.
• W2062817549 hasRelatedWork W2007194872 @default.
• W2062817549 hasRelatedWork W2033247222 @default.

• next