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- W2062831952 abstract "To ascertain antimicrobial susceptibility profile of Proteus mirabilis ( P. mirabilis ) from clinical urine specimens at a university hospital in the spate of its recorded increasing resistance patterns. The study was retrospective in nature. Data generated from urine cultures of patients at University of Calabar Teaching Hospital for a period of five years (2004–2009) were compiled. Relevant information obtained were age and gender of patients, organisms recovered and their antibiotic susceptibility patterns. P. mirabilis was identified using standard laboratory procedures. P. mirabilis showed the highest resistance against ampicillin, cloxacillin, amoxicillin, tetracycline, co-trimoxazole, erythromycin and chloramphenicol (100%–37.2%) while colistin, ofloxacin, ciprofloxacin, ceftriaxone, nalidixic acid and nitrofurantoin recorded the highest activity (59.1%–96.9%) with no drug recording 100% activity. The resistance of the nosocomial isolates of the organism were significantly higher than the community acquired isolates against that of the common antibiotics in use (P<0.05). Extreme caution should be exercised in antibiotic administration in hospital setting and the potential benefits adequately assessed while control of nosocomial infections be given a priority so as to limit the spread of resistant bacteria." @default.
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- W2062831952 date "2012-02-01" @default.
- W2062831952 modified "2023-10-15" @default.
- W2062831952 title "Nosocomial and community acquired uropathogenic isolates of Proteus mirabilis and antimicrobial susceptibility profiles at a university hospital in Sub–Saharan Africa" @default.
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- W2062831952 doi "https://doi.org/10.1016/s2222-1808(12)60003-6" @default.
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