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- W2062843759 abstract "The decomposition of the variance of the average heterozygosity into variances between and within populations is studied in the general case of a finite number of loci. These loci are assumed randomly distributed over chromosome pairs having a non-interference recombination scheme, and independently subject to mutation according to the infinite-allele model. The equilibrium behavior of that decomposition is discussed in the monoecious mating case with regard to each parameter of the model: mutation rate per gene per generation (u), population size (N), number of loci (n), map length of chomosome pairs (L). It is shown that the proportion Q of the between-population variability in the total variance of the average heterozygosity is decreasing as either the mean heterozygosity (θ = 4Nu/(1 + 4Nu)) or the mean number of mutations per gamete per generation (v = nu) is increasing. Moreover, even if Q is always smaller than 13 for this model, it is not negligible unless θ is close to one or v is much larger than one for L long enough." @default.
- W2062843759 created "2016-06-24" @default.
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- W2062843759 date "1981-12-01" @default.
- W2062843759 modified "2023-09-25" @default.
- W2062843759 title "Is the between-population variance negligible in the total variance of heterozygosity? Case of a finite number of loci subject to the infinite-allele model in finite monoecious populations" @default.
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- W2062843759 doi "https://doi.org/10.1016/0040-5809(81)90054-x" @default.
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