FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062868425> ?p ?o ?g. }

• W2062868425 endingPage "244" @default.
• W2062868425 startingPage "236" @default.
• W2062868425 abstract "Synaptic dysfunction has recently gained attention for its involvement in mood disorders. Electroconvulsive therapy (ECT) possibly plays a role in synaptic repair. However, the underlying mechanisms remain uncertain. Thrombospondin-1 (TSP-1), a member of the TSP family, is reported to be secreted by astrocytes and to regulate synaptogenesis. We investigated the effects of electroconvulsive seizure (ECS) on the expression of TSPs in the adult rat hippocampus. Single and repeated ECS significantly increased TSP-1 mRNA expression after 2 h and returned to sham levels at 24 h. Conversely, the TSP-2 and -4 mRNA levels did not change. Only repeated ECS induced TSP-1 proteins. ECS also induced glial fibrillary acidic protein (GFAP) expression. The GFAP expression occurred later than the TSP-1 mRNA expression following single ECS; however, it occurred earlier and was more persistent following repeated ECS. ECS had no effect on the α2δ-1 or neuroligin-1 expressions, both of which are TSP-1 receptors. Furthermore, chronic treatment with antidepressants did not induce the expression of TSP-1 or GFAP. These findings suggest that repeated ECS, but not chronic treatment with antidepressants, induces TSP-1 expression partially via the activation of astrocytes. Therefore, TSP-1 is possibly involved in the synaptogenic effects of ECS." @default.
• W2062868425 created "2016-06-24" @default.
• W2062868425 creator A5002181472 @default.
• W2062868425 creator A5011102342 @default.
• W2062868425 creator A5046095148 @default.
• W2062868425 creator A5051571606 @default.
• W2062868425 creator A5066885799 @default.
• W2062868425 creator A5073047222 @default.
• W2062868425 creator A5086724485 @default.
• W2062868425 date "2014-01-01" @default.
• W2062868425 modified "2023-10-16" @default.
• W2062868425 title "Electroconvulsive seizure induces thrombospondin-1 in the adult rat hippocampus" @default.
• W2062868425 cites W1497663490 @default.
• W2062868425 cites W1973125755 @default.
• W2062868425 cites W1974271139 @default.
• W2062868425 cites W1975787020 @default.
• W2062868425 cites W1983109693 @default.
• W2062868425 cites W1988452935 @default.
• W2062868425 cites W1992958350 @default.
• W2062868425 cites W1995493368 @default.
• W2062868425 cites W1996626446 @default.
• W2062868425 cites W1998628114 @default.
• W2062868425 cites W2012935976 @default.
• W2062868425 cites W2017132462 @default.
• W2062868425 cites W2022149149 @default.
• W2062868425 cites W2025582889 @default.
• W2062868425 cites W2026147918 @default.
• W2062868425 cites W2026807633 @default.
• W2062868425 cites W2026813655 @default.
• W2062868425 cites W2036755685 @default.
• W2062868425 cites W2044730840 @default.
• W2062868425 cites W2048033931 @default.
• W2062868425 cites W2059940674 @default.
• W2062868425 cites W2068787795 @default.
• W2062868425 cites W2083739539 @default.
• W2062868425 cites W2089351762 @default.
• W2062868425 cites W2089686007 @default.
• W2062868425 cites W2095555809 @default.
• W2062868425 cites W2098622411 @default.
• W2062868425 cites W2106165895 @default.
• W2062868425 cites W2124940469 @default.
• W2062868425 cites W2127087678 @default.
• W2062868425 cites W2152284832 @default.
• W2062868425 cites W2154797040 @default.
• W2062868425 cites W2157504436 @default.
• W2062868425 cites W2159229968 @default.
• W2062868425 cites W2159494007 @default.
• W2062868425 cites W2160229338 @default.
• W2062868425 cites W4256132137 @default.
• W2062868425 cites W70078742 @default.
• W2062868425 doi "https://doi.org/10.1016/j.pnpbp.2013.10.001" @default.
• W2062868425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24121060" @default.
• W2062868425 hasPublicationYear "2014" @default.
• W2062868425 type Work @default.
• W2062868425 sameAs 2062868425 @default.
• W2062868425 citedByCount "26" @default.
• W2062868425 countsByYear W20628684252015 @default.
• W2062868425 countsByYear W20628684252016 @default.
• W2062868425 countsByYear W20628684252017 @default.
• W2062868425 countsByYear W20628684252018 @default.
• W2062868425 countsByYear W20628684252019 @default.
• W2062868425 countsByYear W20628684252020 @default.
• W2062868425 countsByYear W20628684252021 @default.
• W2062868425 countsByYear W20628684252022 @default.
• W2062868425 countsByYear W20628684252023 @default.
• W2062868425 crossrefType "journal-article" @default.
• W2062868425 hasAuthorship W2062868425A5002181472 @default.
• W2062868425 hasAuthorship W2062868425A5011102342 @default.
• W2062868425 hasAuthorship W2062868425A5046095148 @default.
• W2062868425 hasAuthorship W2062868425A5051571606 @default.
• W2062868425 hasAuthorship W2062868425A5066885799 @default.
• W2062868425 hasAuthorship W2062868425A5073047222 @default.
• W2062868425 hasAuthorship W2062868425A5086724485 @default.
• W2062868425 hasConcept C109523444 @default.
• W2062868425 hasConcept C126322002 @default.
• W2062868425 hasConcept C134018914 @default.
• W2062868425 hasConcept C15744967 @default.
• W2062868425 hasConcept C167814343 @default.
• W2062868425 hasConcept C169760540 @default.
• W2062868425 hasConcept C170493617 @default.
• W2062868425 hasConcept C204232928 @default.
• W2062868425 hasConcept C2777330709 @default.
• W2062868425 hasConcept C2780394083 @default.
• W2062868425 hasConcept C2780495277 @default.
• W2062868425 hasConcept C2781161787 @default.
• W2062868425 hasConcept C2910926394 @default.
• W2062868425 hasConcept C55728118 @default.
• W2062868425 hasConcept C65232495 @default.
• W2062868425 hasConcept C71924100 @default.
• W2062868425 hasConcept C86803240 @default.
• W2062868425 hasConcept C99194444 @default.
• W2062868425 hasConceptScore W2062868425C109523444 @default.
• W2062868425 hasConceptScore W2062868425C126322002 @default.
• W2062868425 hasConceptScore W2062868425C134018914 @default.
• W2062868425 hasConceptScore W2062868425C15744967 @default.
• W2062868425 hasConceptScore W2062868425C167814343 @default.
• W2062868425 hasConceptScore W2062868425C169760540 @default.
• W2062868425 hasConceptScore W2062868425C170493617 @default.

• next