Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062889098> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2062889098 abstract "The effects of scrapie agent on local cerebral energy metabolism were studied by the [14C]2-deoxyglucose (2-DG) autoradiographic method of Sokoloff et al. after stereomicroinoculation (0.5 microliter, 10(-2) of scrapie suspension) in hamster left striatum. From a group of 20 hamsters inoculated, 2 animals were killed every 10 days from the 30th day after inoculation to the terminal stage of the disease. Experiments were carried out according to the qualitative 2-DG procedure and cerebral autoradiographs of inoculated animals were compared to those of 3 controls. The results show changes of local cerebral glucose utilization in some discrete brain regions, ipsilateral to the side of inoculation, and their sequential spreading to other cerebral structures with a definite order: left anterior thalamus, left posterior thalamus, then medial geniculate body (ipsilateral, then controlateral), and finally some brainstem nuclei (inferior colliculus, superior olivary nucleus); the inoculated striatum is affected very late, after clinical signs. Metabolic changes which first occur ipsilaterally to the side of inoculation precede the clinical symptoms, while their contralateral spreading is concomitant with the clinical signs. The data demonstrate a rostral--caudal sequence of the cerebral metabolic changes, ipsilateral to the side of inoculation, which may reflect in part the slow spread of agent in the central nervous system from the inoculation site." @default.
- W2062889098 created "2016-06-24" @default.
- W2062889098 creator A5008525421 @default.
- W2062889098 creator A5028620615 @default.
- W2062889098 creator A5030261347 @default.
- W2062889098 creator A5053754870 @default.
- W2062889098 creator A5080849427 @default.
- W2062889098 date "1983-04-01" @default.
- W2062889098 modified "2023-09-27" @default.
- W2062889098 title "Cerebral glucose utilization: Local changes after microinoculation of scrapie agent in hamster" @default.
- W2062889098 cites W1991090581 @default.
- W2062889098 cites W1993357915 @default.
- W2062889098 cites W2027234732 @default.
- W2062889098 cites W2047086207 @default.
- W2062889098 cites W2054891157 @default.
- W2062889098 cites W2090306035 @default.
- W2062889098 cites W2094251808 @default.
- W2062889098 cites W2282824187 @default.
- W2062889098 cites W2419062902 @default.
- W2062889098 cites W2401269904 @default.
- W2062889098 doi "https://doi.org/10.1016/0304-3940(83)90262-8" @default.
- W2062889098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6683389" @default.
- W2062889098 hasPublicationYear "1983" @default.
- W2062889098 type Work @default.
- W2062889098 sameAs 2062889098 @default.
- W2062889098 citedByCount "10" @default.
- W2062889098 countsByYear W20628890982012 @default.
- W2062889098 crossrefType "journal-article" @default.
- W2062889098 hasAuthorship W2062889098A5008525421 @default.
- W2062889098 hasAuthorship W2062889098A5028620615 @default.
- W2062889098 hasAuthorship W2062889098A5030261347 @default.
- W2062889098 hasAuthorship W2062889098A5053754870 @default.
- W2062889098 hasAuthorship W2062889098A5080849427 @default.
- W2062889098 hasConcept C105702510 @default.
- W2062889098 hasConcept C126322002 @default.
- W2062889098 hasConcept C134018914 @default.
- W2062889098 hasConcept C169760540 @default.
- W2062889098 hasConcept C2775980177 @default.
- W2062889098 hasConcept C2776735649 @default.
- W2062889098 hasConcept C2778474254 @default.
- W2062889098 hasConcept C2778575167 @default.
- W2062889098 hasConcept C2779134260 @default.
- W2062889098 hasConcept C2779246727 @default.
- W2062889098 hasConcept C2780062018 @default.
- W2062889098 hasConcept C2780723820 @default.
- W2062889098 hasConcept C2781041448 @default.
- W2062889098 hasConcept C2909708642 @default.
- W2062889098 hasConcept C3019804061 @default.
- W2062889098 hasConcept C513476851 @default.
- W2062889098 hasConcept C529278444 @default.
- W2062889098 hasConcept C552161191 @default.
- W2062889098 hasConcept C71924100 @default.
- W2062889098 hasConcept C86803240 @default.
- W2062889098 hasConceptScore W2062889098C105702510 @default.
- W2062889098 hasConceptScore W2062889098C126322002 @default.
- W2062889098 hasConceptScore W2062889098C134018914 @default.
- W2062889098 hasConceptScore W2062889098C169760540 @default.
- W2062889098 hasConceptScore W2062889098C2775980177 @default.
- W2062889098 hasConceptScore W2062889098C2776735649 @default.
- W2062889098 hasConceptScore W2062889098C2778474254 @default.
- W2062889098 hasConceptScore W2062889098C2778575167 @default.
- W2062889098 hasConceptScore W2062889098C2779134260 @default.
- W2062889098 hasConceptScore W2062889098C2779246727 @default.
- W2062889098 hasConceptScore W2062889098C2780062018 @default.
- W2062889098 hasConceptScore W2062889098C2780723820 @default.
- W2062889098 hasConceptScore W2062889098C2781041448 @default.
- W2062889098 hasConceptScore W2062889098C2909708642 @default.
- W2062889098 hasConceptScore W2062889098C3019804061 @default.
- W2062889098 hasConceptScore W2062889098C513476851 @default.
- W2062889098 hasConceptScore W2062889098C529278444 @default.
- W2062889098 hasConceptScore W2062889098C552161191 @default.
- W2062889098 hasConceptScore W2062889098C71924100 @default.
- W2062889098 hasConceptScore W2062889098C86803240 @default.
- W2062889098 hasLocation W20628890981 @default.
- W2062889098 hasLocation W20628890982 @default.
- W2062889098 hasOpenAccess W2062889098 @default.
- W2062889098 hasPrimaryLocation W20628890981 @default.
- W2062889098 hasRelatedWork W2019552131 @default.
- W2062889098 hasRelatedWork W2058149053 @default.
- W2062889098 hasRelatedWork W2058231178 @default.
- W2062889098 hasRelatedWork W2059941532 @default.
- W2062889098 hasRelatedWork W2062889098 @default.
- W2062889098 hasRelatedWork W2067434670 @default.
- W2062889098 hasRelatedWork W2085737607 @default.
- W2062889098 hasRelatedWork W2382741518 @default.
- W2062889098 hasRelatedWork W3010654070 @default.
- W2062889098 hasRelatedWork W3083984862 @default.
- W2062889098 isParatext "false" @default.
- W2062889098 isRetracted "false" @default.
- W2062889098 magId "2062889098" @default.
- W2062889098 workType "article" @default.