Matches in SemOpenAlex for { <https://semopenalex.org/work/W2062953018> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2062953018 endingPage "769" @default.
- W2062953018 startingPage "762" @default.
- W2062953018 abstract "Cytochrome P450 (CP450) catalyzed oxidative metabolism of carbofuran (1), carbaryl (2), and pirimicarb (3) has been modeled using biomimetic oxidations catalyzed by iron(III) tetraarylporphyrins. Oxidation products of 1 were identified by comparison of HPLC retention times measured under standardized conditions for metabolites synthesized and characterized by (1)H and (13)C NMR spectroscopy. Comparison of product distributions to in vivo metabolic profiles revealed that the H(2)O(2)/meso-tetrakis(pentafluorophenyl)porphyrin iron(III) chloride [Fe(TF(20)PP)] system mimics the action of insect CP450s against carbofuran. The effectiveness of this system was further demonstrated by the biomimetic oxidation of other carbamate insecticides (2 and 3) monitored by HPLC/electrospray MS. The predictive power of this biomimetic model was compared to that of knowledge-based expert systems. Although similar models were recently applied in pharmaceutical research, the usefulness of this approach has first been demonstrated for the prediction of metabolic profiles of agrochemicals." @default.
- W2062953018 created "2016-06-24" @default.
- W2062953018 creator A5018133234 @default.
- W2062953018 creator A5020753663 @default.
- W2062953018 creator A5022888378 @default.
- W2062953018 creator A5026142517 @default.
- W2062953018 creator A5044690551 @default.
- W2062953018 creator A5066739988 @default.
- W2062953018 date "1999-01-26" @default.
- W2062953018 modified "2023-10-18" @default.
- W2062953018 title "Chemical Models of Cytochrome P450 Catalyzed Insecticide Metabolism. Application to the Oxidative Metabolism of Carbamate Insecticides" @default.
- W2062953018 cites W1583977177 @default.
- W2062953018 cites W1975755330 @default.
- W2062953018 cites W1986753688 @default.
- W2062953018 cites W1988163318 @default.
- W2062953018 cites W1993625621 @default.
- W2062953018 cites W2001994367 @default.
- W2062953018 cites W2010486872 @default.
- W2062953018 cites W2041328598 @default.
- W2062953018 cites W2063887000 @default.
- W2062953018 cites W2073928749 @default.
- W2062953018 cites W2080033943 @default.
- W2062953018 cites W2090264326 @default.
- W2062953018 cites W2106814193 @default.
- W2062953018 cites W211920609 @default.
- W2062953018 cites W2193086126 @default.
- W2062953018 cites W2365639806 @default.
- W2062953018 cites W4210769220 @default.
- W2062953018 cites W4293282011 @default.
- W2062953018 doi "https://doi.org/10.1021/jf980347+" @default.
- W2062953018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10563966" @default.
- W2062953018 hasPublicationYear "1999" @default.
- W2062953018 type Work @default.
- W2062953018 sameAs 2062953018 @default.
- W2062953018 citedByCount "20" @default.
- W2062953018 countsByYear W20629530182015 @default.
- W2062953018 countsByYear W20629530182022 @default.
- W2062953018 crossrefType "journal-article" @default.
- W2062953018 hasAuthorship W2062953018A5018133234 @default.
- W2062953018 hasAuthorship W2062953018A5020753663 @default.
- W2062953018 hasAuthorship W2062953018A5022888378 @default.
- W2062953018 hasAuthorship W2062953018A5026142517 @default.
- W2062953018 hasAuthorship W2062953018A5044690551 @default.
- W2062953018 hasAuthorship W2062953018A5066739988 @default.
- W2062953018 hasConcept C161176658 @default.
- W2062953018 hasConcept C181199279 @default.
- W2062953018 hasConcept C185592680 @default.
- W2062953018 hasConcept C2776051353 @default.
- W2062953018 hasConcept C2777477808 @default.
- W2062953018 hasConcept C2779303437 @default.
- W2062953018 hasConcept C2780862241 @default.
- W2062953018 hasConcept C2781109383 @default.
- W2062953018 hasConcept C2781401687 @default.
- W2062953018 hasConcept C43617362 @default.
- W2062953018 hasConcept C526171541 @default.
- W2062953018 hasConcept C55493867 @default.
- W2062953018 hasConcept C57600042 @default.
- W2062953018 hasConcept C62231903 @default.
- W2062953018 hasConcept C6557445 @default.
- W2062953018 hasConcept C86803240 @default.
- W2062953018 hasConceptScore W2062953018C161176658 @default.
- W2062953018 hasConceptScore W2062953018C181199279 @default.
- W2062953018 hasConceptScore W2062953018C185592680 @default.
- W2062953018 hasConceptScore W2062953018C2776051353 @default.
- W2062953018 hasConceptScore W2062953018C2777477808 @default.
- W2062953018 hasConceptScore W2062953018C2779303437 @default.
- W2062953018 hasConceptScore W2062953018C2780862241 @default.
- W2062953018 hasConceptScore W2062953018C2781109383 @default.
- W2062953018 hasConceptScore W2062953018C2781401687 @default.
- W2062953018 hasConceptScore W2062953018C43617362 @default.
- W2062953018 hasConceptScore W2062953018C526171541 @default.
- W2062953018 hasConceptScore W2062953018C55493867 @default.
- W2062953018 hasConceptScore W2062953018C57600042 @default.
- W2062953018 hasConceptScore W2062953018C62231903 @default.
- W2062953018 hasConceptScore W2062953018C6557445 @default.
- W2062953018 hasConceptScore W2062953018C86803240 @default.
- W2062953018 hasIssue "2" @default.
- W2062953018 hasLocation W20629530181 @default.
- W2062953018 hasLocation W20629530182 @default.
- W2062953018 hasOpenAccess W2062953018 @default.
- W2062953018 hasPrimaryLocation W20629530181 @default.
- W2062953018 hasRelatedWork W1968847994 @default.
- W2062953018 hasRelatedWork W1978872362 @default.
- W2062953018 hasRelatedWork W2062145926 @default.
- W2062953018 hasRelatedWork W2065179077 @default.
- W2062953018 hasRelatedWork W2075846655 @default.
- W2062953018 hasRelatedWork W2080704802 @default.
- W2062953018 hasRelatedWork W2118545690 @default.
- W2062953018 hasRelatedWork W2364613358 @default.
- W2062953018 hasRelatedWork W2370744822 @default.
- W2062953018 hasRelatedWork W2381958489 @default.
- W2062953018 hasVolume "47" @default.
- W2062953018 isParatext "false" @default.
- W2062953018 isRetracted "false" @default.
- W2062953018 magId "2062953018" @default.
- W2062953018 workType "article" @default.