Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063020863> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2063020863 endingPage "156" @default.
- W2063020863 startingPage "151" @default.
- W2063020863 abstract "Thirty-two healthy men and women, 23 to 78 yr old, received single 650-mg intravenous doses of acetaminophen and the drug's kinetics were determined from multiple plasma samples drawn over the next 8 to 12 hr. Acetaminophen elimination half-life averaged 2.7 hr (range, 1.9 to 4.3 hr) and was not related to age or sex. Volume of distribution (corrected for weight) was larger in men than in women (0.99 and 0.86 l/kg) and declined with age in both sexes. This probably reflects increased fat per kilogram body weight in women and in the elderly, together with incomplete distribution of this nonlipophilic drug into body fat. Acetaminophen clearance tended to decline with age in both sexes, but differences were of borderline significance. On the basis of kinetics data alone, adjustment of acetaminophen dosage for the elderly is generally not necessary." @default.
- W2063020863 created "2016-06-24" @default.
- W2063020863 creator A5018546198 @default.
- W2063020863 creator A5028460883 @default.
- W2063020863 creator A5085911565 @default.
- W2063020863 creator A5087737186 @default.
- W2063020863 date "1982-02-01" @default.
- W2063020863 modified "2023-10-16" @default.
- W2063020863 title "Acetaminophen kinetics in the elderly" @default.
- W2063020863 cites W1968275730 @default.
- W2063020863 cites W1999852053 @default.
- W2063020863 cites W2003225109 @default.
- W2063020863 cites W2010669389 @default.
- W2063020863 cites W2087070363 @default.
- W2063020863 cites W2102098971 @default.
- W2063020863 cites W2291058680 @default.
- W2063020863 cites W2409800341 @default.
- W2063020863 cites W2412683438 @default.
- W2063020863 cites W2423092877 @default.
- W2063020863 cites W2613223189 @default.
- W2063020863 doi "https://doi.org/10.1038/clpt.1982.24" @default.
- W2063020863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7056022" @default.
- W2063020863 hasPublicationYear "1982" @default.
- W2063020863 type Work @default.
- W2063020863 sameAs 2063020863 @default.
- W2063020863 citedByCount "84" @default.
- W2063020863 countsByYear W20630208632014 @default.
- W2063020863 countsByYear W20630208632015 @default.
- W2063020863 countsByYear W20630208632016 @default.
- W2063020863 countsByYear W20630208632017 @default.
- W2063020863 countsByYear W20630208632018 @default.
- W2063020863 countsByYear W20630208632019 @default.
- W2063020863 countsByYear W20630208632022 @default.
- W2063020863 countsByYear W20630208632023 @default.
- W2063020863 crossrefType "journal-article" @default.
- W2063020863 hasAuthorship W2063020863A5018546198 @default.
- W2063020863 hasAuthorship W2063020863A5028460883 @default.
- W2063020863 hasAuthorship W2063020863A5085911565 @default.
- W2063020863 hasAuthorship W2063020863A5087737186 @default.
- W2063020863 hasConcept C112705442 @default.
- W2063020863 hasConcept C120863210 @default.
- W2063020863 hasConcept C121332964 @default.
- W2063020863 hasConcept C126322002 @default.
- W2063020863 hasConcept C139254425 @default.
- W2063020863 hasConcept C147583825 @default.
- W2063020863 hasConcept C148898269 @default.
- W2063020863 hasConcept C207892153 @default.
- W2063020863 hasConcept C2778722691 @default.
- W2063020863 hasConcept C2991747820 @default.
- W2063020863 hasConcept C3018403923 @default.
- W2063020863 hasConcept C42219234 @default.
- W2063020863 hasConcept C62520636 @default.
- W2063020863 hasConcept C71924100 @default.
- W2063020863 hasConceptScore W2063020863C112705442 @default.
- W2063020863 hasConceptScore W2063020863C120863210 @default.
- W2063020863 hasConceptScore W2063020863C121332964 @default.
- W2063020863 hasConceptScore W2063020863C126322002 @default.
- W2063020863 hasConceptScore W2063020863C139254425 @default.
- W2063020863 hasConceptScore W2063020863C147583825 @default.
- W2063020863 hasConceptScore W2063020863C148898269 @default.
- W2063020863 hasConceptScore W2063020863C207892153 @default.
- W2063020863 hasConceptScore W2063020863C2778722691 @default.
- W2063020863 hasConceptScore W2063020863C2991747820 @default.
- W2063020863 hasConceptScore W2063020863C3018403923 @default.
- W2063020863 hasConceptScore W2063020863C42219234 @default.
- W2063020863 hasConceptScore W2063020863C62520636 @default.
- W2063020863 hasConceptScore W2063020863C71924100 @default.
- W2063020863 hasIssue "2" @default.
- W2063020863 hasLocation W20630208631 @default.
- W2063020863 hasLocation W20630208632 @default.
- W2063020863 hasOpenAccess W2063020863 @default.
- W2063020863 hasPrimaryLocation W20630208631 @default.
- W2063020863 hasRelatedWork W1975326190 @default.
- W2063020863 hasRelatedWork W1982443836 @default.
- W2063020863 hasRelatedWork W1988674255 @default.
- W2063020863 hasRelatedWork W1997066199 @default.
- W2063020863 hasRelatedWork W2058986278 @default.
- W2063020863 hasRelatedWork W2063020863 @default.
- W2063020863 hasRelatedWork W2409584343 @default.
- W2063020863 hasRelatedWork W2410427007 @default.
- W2063020863 hasRelatedWork W2468737134 @default.
- W2063020863 hasRelatedWork W4361004422 @default.
- W2063020863 hasVolume "31" @default.
- W2063020863 isParatext "false" @default.
- W2063020863 isRetracted "false" @default.
- W2063020863 magId "2063020863" @default.
- W2063020863 workType "article" @default.