FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063022214> ?p ?o ?g. }

• W2063022214 endingPage "1134" @default.
• W2063022214 startingPage "1128" @default.
• W2063022214 abstract "Purpose Endothelin-1, prostaglandins (PGs), and nitric oxide (NO) have been implicated in the intestinal microvascular dysfunction of necrotizing enterocolitis (NEC). We hypothesized that direct peritoneal resuscitation (DPR) dilates the intestinal microvasculature and improves blood flow independent of these mechanisms. Methods Rat pups were assigned by litter to experimental NEC or CONTROL groups. Laser Doppler flowmetry evaluation of intestinal microvascular blood flow was studied at baseline, with mediator blockade (endothelin-A receptor, endothelin-B receptor, PG synthesis, or NO synthase) and with DPR. Repeated-measures analysis of variance test was applied with Tukey-Kramer honestly significant difference test (P < .05). Results At baseline, NEC animals demonstrated significantly decreased ileal blood flow as compared with CONTROLs (P < .05). Endothelin-A receptor and PG inhibition increased flow in the intestinal microvasculature, but this was significantly augmented by the addition of DPR (P < .05). Blockade of NO synthase decreased intestinal blood flow, which was overcome with addition of DPR (P < .05). Conclusion Ileal blood flow was significantly reduced in NEC animals as compared with CONTROLs. The addition of DPR to the peritoneum increased ileal blood flow significantly in all groups in spite of blockade of these known vasoactive mechanisms. Direct peritoneal resuscitation may be a novel strategy to improve intestinal blood flow in NEC." @default.
• W2063022214 created "2016-06-24" @default.
• W2063022214 creator A5000210829 @default.
• W2063022214 creator A5018105198 @default.
• W2063022214 creator A5033725162 @default.
• W2063022214 creator A5067437019 @default.
• W2063022214 creator A5073013948 @default.
• W2063022214 date "2012-06-01" @default.
• W2063022214 modified "2023-09-27" @default.
• W2063022214 title "Direct peritoneal resuscitation augments ileal blood flow in necrotizing enterocolitis via a novel mechanism" @default.
• W2063022214 cites W1966017962 @default.
• W2063022214 cites W1966487525 @default.
• W2063022214 cites W1967789917 @default.
• W2063022214 cites W1968961107 @default.
• W2063022214 cites W1971015436 @default.
• W2063022214 cites W1974809420 @default.
• W2063022214 cites W1977527748 @default.
• W2063022214 cites W1982188613 @default.
• W2063022214 cites W1986138196 @default.
• W2063022214 cites W1991485851 @default.
• W2063022214 cites W2012611711 @default.
• W2063022214 cites W2018750501 @default.
• W2063022214 cites W2023495203 @default.
• W2063022214 cites W2042281074 @default.
• W2063022214 cites W2051326485 @default.
• W2063022214 cites W2077825367 @default.
• W2063022214 cites W2078473047 @default.
• W2063022214 cites W2078768544 @default.
• W2063022214 cites W2078965259 @default.
• W2063022214 cites W2085319013 @default.
• W2063022214 cites W2086072225 @default.
• W2063022214 cites W2091356199 @default.
• W2063022214 cites W2096579470 @default.
• W2063022214 cites W2133163355 @default.
• W2063022214 cites W2148952060 @default.
• W2063022214 cites W2161858872 @default.
• W2063022214 cites W2188379545 @default.
• W2063022214 cites W2237475035 @default.
• W2063022214 cites W2282406415 @default.
• W2063022214 cites W4252096944 @default.
• W2063022214 cites W72496549 @default.
• W2063022214 doi "https://doi.org/10.1016/j.jpedsurg.2012.03.017" @default.
• W2063022214 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22703782" @default.
• W2063022214 hasPublicationYear "2012" @default.
• W2063022214 type Work @default.
• W2063022214 sameAs 2063022214 @default.
• W2063022214 citedByCount "9" @default.
• W2063022214 countsByYear W20630222142013 @default.
• W2063022214 countsByYear W20630222142014 @default.
• W2063022214 countsByYear W20630222142016 @default.
• W2063022214 countsByYear W20630222142017 @default.
• W2063022214 countsByYear W20630222142019 @default.
• W2063022214 countsByYear W20630222142022 @default.
• W2063022214 crossrefType "journal-article" @default.
• W2063022214 hasAuthorship W2063022214A5000210829 @default.
• W2063022214 hasAuthorship W2063022214A5018105198 @default.
• W2063022214 hasAuthorship W2063022214A5033725162 @default.
• W2063022214 hasAuthorship W2063022214A5067437019 @default.
• W2063022214 hasAuthorship W2063022214A5073013948 @default.
• W2063022214 hasConcept C126322002 @default.
• W2063022214 hasConcept C134018914 @default.
• W2063022214 hasConcept C144980905 @default.
• W2063022214 hasConcept C158846371 @default.
• W2063022214 hasConcept C170493617 @default.
• W2063022214 hasConcept C2778165595 @default.
• W2063022214 hasConcept C2778468042 @default.
• W2063022214 hasConcept C2779303187 @default.
• W2063022214 hasConcept C2780199535 @default.
• W2063022214 hasConcept C42219234 @default.
• W2063022214 hasConcept C519581460 @default.
• W2063022214 hasConcept C52305850 @default.
• W2063022214 hasConcept C71924100 @default.
• W2063022214 hasConceptScore W2063022214C126322002 @default.
• W2063022214 hasConceptScore W2063022214C134018914 @default.
• W2063022214 hasConceptScore W2063022214C144980905 @default.
• W2063022214 hasConceptScore W2063022214C158846371 @default.
• W2063022214 hasConceptScore W2063022214C170493617 @default.
• W2063022214 hasConceptScore W2063022214C2778165595 @default.
• W2063022214 hasConceptScore W2063022214C2778468042 @default.
• W2063022214 hasConceptScore W2063022214C2779303187 @default.
• W2063022214 hasConceptScore W2063022214C2780199535 @default.
• W2063022214 hasConceptScore W2063022214C42219234 @default.
• W2063022214 hasConceptScore W2063022214C519581460 @default.
• W2063022214 hasConceptScore W2063022214C52305850 @default.
• W2063022214 hasConceptScore W2063022214C71924100 @default.
• W2063022214 hasIssue "6" @default.
• W2063022214 hasLocation W20630222141 @default.
• W2063022214 hasLocation W20630222142 @default.
• W2063022214 hasOpenAccess W2063022214 @default.
• W2063022214 hasPrimaryLocation W20630222141 @default.
• W2063022214 hasRelatedWork W1983371938 @default.
• W2063022214 hasRelatedWork W1996846474 @default.
• W2063022214 hasRelatedWork W2018368842 @default.
• W2063022214 hasRelatedWork W2033472167 @default.
• W2063022214 hasRelatedWork W2034583712 @default.
• W2063022214 hasRelatedWork W2052453588 @default.
• W2063022214 hasRelatedWork W2061429094 @default.
• W2063022214 hasRelatedWork W2063619316 @default.

• next