FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063025483> ?p ?o ?g. }

• W2063025483 endingPage "13" @default.
• W2063025483 startingPage "8" @default.
• W2063025483 abstract "Background: The efficacy and safety of conversion treatment with sirolimus in renal transplant recipients using the calcineurin inhibitor (CNI) with one or more risk factors was evaluated. Methods: Ninety-three renal transplant recipients were prospectively enrolled. CNIs(CsA and FK506) as main immunosuppressant were converted to SRL immunosuppressant protocol. Rapid conversion with si-rolimus was performed in all patients. The CNI withdrawal was in 2 weeks. At 4 hours after oral administration of cyclosporin A or tacrolimus, the patients took sirolimus. Initial dose of sirolimus was 6 mg, and repeated maintenance dose is 1.0 - 2.0 mg/d. The first concentration of sirolimus was detected at 5 - 7 days after first oral administration, and the target concentration was 6 - 10 μg/L. Results: The symptoms were markedly improved in patients with CNI induced renal toxicity and CNI induced liver toxicity, and the concentration of sirolimus were maintained at (5.1 ± 1.2) μg/L. Serum creatinine levels decreased from (297.72 ± 150.28) μmol/L to (123.76 ± 44.2) μmol/L, and the liver function were recovery in 24 (92.3%) patients. 9 patients with high glucose returned to normal, and 2 patients were improved. Serum creatinine levels decreased more than 25% of primary level in 17 patients, and the effective rate was 51.5%. 10 patients with tumor were appeared 6 - 43 months after renal transplantation, no recurrence was found in 8 of them and 2 patients were dead. Acute rejections were occurred in 3 patients at 6 months after conversion treatment. The complications were included hyperlipidemia and proteinuria. 3 patients were dead, 6 patients returned to dialysis treatment, and 2 patients were removal of grafts. At 3 years after conversion treatment, the survival rates of patients and grafts were 90.9% and 75.8%, respectively. Conclusion: The conversion treatment with SRL and MMF may be a better option for the renal transplant recipients using the CNI with risk factors appeared." @default.
• W2063025483 created "2016-06-24" @default.
• W2063025483 creator A5007054845 @default.
• W2063025483 creator A5032597919 @default.
• W2063025483 creator A5050943142 @default.
• W2063025483 creator A5054094651 @default.
• W2063025483 creator A5055588065 @default.
• W2063025483 creator A5090067601 @default.
• W2063025483 date "2011-01-01" @default.
• W2063025483 modified "2023-09-30" @default.
• W2063025483 title "Conversion from Calcineurin Inhibitors to Sirolimus Maintenance Therapy in Renal Allograft Recipients with Risk Factors" @default.
• W2063025483 cites W1982231207 @default.
• W2063025483 cites W2005128153 @default.
• W2063025483 cites W2021137320 @default.
• W2063025483 cites W2024863238 @default.
• W2063025483 cites W2049580582 @default.
• W2063025483 cites W2051763571 @default.
• W2063025483 cites W2055840660 @default.
• W2063025483 cites W2061071218 @default.
• W2063025483 cites W2073178544 @default.
• W2063025483 cites W2115061192 @default.
• W2063025483 cites W2138620116 @default.
• W2063025483 cites W2145644068 @default.
• W2063025483 cites W2168286678 @default.
• W2063025483 cites W22166133 @default.
• W2063025483 doi "https://doi.org/10.4236/ojots.2011.11002" @default.
• W2063025483 hasPublicationYear "2011" @default.
• W2063025483 type Work @default.
• W2063025483 sameAs 2063025483 @default.
• W2063025483 citedByCount "0" @default.
• W2063025483 crossrefType "journal-article" @default.
• W2063025483 hasAuthorship W2063025483A5007054845 @default.
• W2063025483 hasAuthorship W2063025483A5032597919 @default.
• W2063025483 hasAuthorship W2063025483A5050943142 @default.
• W2063025483 hasAuthorship W2063025483A5054094651 @default.
• W2063025483 hasAuthorship W2063025483A5055588065 @default.
• W2063025483 hasAuthorship W2063025483A5090067601 @default.
• W2063025483 hasBestOaLocation W20630254831 @default.
• W2063025483 hasConcept C126322002 @default.
• W2063025483 hasConcept C126894567 @default.
• W2063025483 hasConcept C128057223 @default.
• W2063025483 hasConcept C159641895 @default.
• W2063025483 hasConcept C2777921159 @default.
• W2063025483 hasConcept C2780306776 @default.
• W2063025483 hasConcept C2909675724 @default.
• W2063025483 hasConcept C2911091166 @default.
• W2063025483 hasConcept C29730261 @default.
• W2063025483 hasConcept C35294091 @default.
• W2063025483 hasConcept C71924100 @default.
• W2063025483 hasConcept C90924648 @default.
• W2063025483 hasConcept C98274493 @default.
• W2063025483 hasConceptScore W2063025483C126322002 @default.
• W2063025483 hasConceptScore W2063025483C126894567 @default.
• W2063025483 hasConceptScore W2063025483C128057223 @default.
• W2063025483 hasConceptScore W2063025483C159641895 @default.
• W2063025483 hasConceptScore W2063025483C2777921159 @default.
• W2063025483 hasConceptScore W2063025483C2780306776 @default.
• W2063025483 hasConceptScore W2063025483C2909675724 @default.
• W2063025483 hasConceptScore W2063025483C2911091166 @default.
• W2063025483 hasConceptScore W2063025483C29730261 @default.
• W2063025483 hasConceptScore W2063025483C35294091 @default.
• W2063025483 hasConceptScore W2063025483C71924100 @default.
• W2063025483 hasConceptScore W2063025483C90924648 @default.
• W2063025483 hasConceptScore W2063025483C98274493 @default.
• W2063025483 hasIssue "01" @default.
• W2063025483 hasLocation W20630254831 @default.
• W2063025483 hasOpenAccess W2063025483 @default.
• W2063025483 hasPrimaryLocation W20630254831 @default.
• W2063025483 hasRelatedWork W1980983627 @default.
• W2063025483 hasRelatedWork W1982767989 @default.
• W2063025483 hasRelatedWork W2009735756 @default.
• W2063025483 hasRelatedWork W2031600833 @default.
• W2063025483 hasRelatedWork W2061071218 @default.
• W2063025483 hasRelatedWork W2063025483 @default.
• W2063025483 hasRelatedWork W2092809732 @default.
• W2063025483 hasRelatedWork W2093178194 @default.
• W2063025483 hasRelatedWork W2333832977 @default.
• W2063025483 hasRelatedWork W2410831871 @default.
• W2063025483 hasVolume "01" @default.
• W2063025483 isParatext "false" @default.
• W2063025483 isRetracted "false" @default.
• W2063025483 magId "2063025483" @default.
• W2063025483 workType "article" @default.