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- W2063032783 abstract "The second type of cytochrome b5 reductase (Cb5R-II) gene was characterized in the arachidonic acid-producing fungus Mortierella alpina 1S-4. Its cDNA (897 bp) and predicted amino acid (298 aa) sequences show more than 70% similarity to the previously isolated first type of Cb5R. Highly conserved exon-intron organization suggests that the two genes evolved from the duplication of a common ancestral gene. Cb5R-II has a flavin-binding domain at its highly hydrophobic N-terminal and an NADH-binding domain at the C-terminal. In comparison with Cb5R genes from other sources, high homology (46-54%) was found for yeast and plant genes. Phylogenetic analysis revealed that microbial and plant Cb5R genes represent a gene family evolved from one prototype and are different from mammalian Cb5R genes." @default.
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- W2063032783 date "1999-01-01" @default.
- W2063032783 modified "2023-09-23" @default.
- W2063032783 title "Characterization of the second form of NADH-Cytochrome b5 reductase gene from arachidonic acid-producing fungus Mortierella alpina 1S-4" @default.
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- W2063032783 doi "https://doi.org/10.1016/s1389-1723(00)87098-x" @default.
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