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- W2063069091 abstract "Antigens present in mouse mammary tumor MM2 reacting with tumor-specific antibodies were extracted with 0.2% deoxycholate. After the removal of deoxycholate by dialysis, most antigens were precipitated by centrifugation at 105,000 × g for 60 min. Hyperimmunization of C3H/He mice with these antigens induced heightened resistance against MM2. Antibodies appeared in the serum after a booster injection of deoxycholate extract of tumor cells was given. Antigens were solubilized from deoxycholate extract with distilled water. Purified soluble antigen inhibited the neutralization activity of the tumor-specific antibody to MM2 tumor. From these observations, it is concluded that transplantation antigens of isografted mammary tumors in C3H/He mice are present in deoxycholate extracts of MM2 tumor." @default.
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- W2063069091 date "1969-03-15" @default.
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- W2063069091 title "Immunological studies on mouse mammary tumors. IV. Extraction and solubilization of transplantation antigen of mouse mammary tumor" @default.
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- W2063069091 doi "https://doi.org/10.1002/ijc.2910040205" @default.
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