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• W2063089076 abstract "Eichenbaum and colleagues observed that the same place did or did not activate the goal-approach cells in hippocampus depending on whether the place was the way for rats to approach specific goal. Parallel with this, the present neuroimage study revealed that, the same type of items could activate the hippocampus more when it was related to the task at hand than when it not. Participants were scanned by fMRI while they made judgments on the type of relationships contained in the word-pairs (e.g., Does the word pair, furniture-table, contain a category-exemplar relationship?). Event-related analysis revealed that the forming of task-related association activated hippocampus more than that of task-unrelated, even if it was the same type of items, and, this hippocampal difference was not caused by the different judgment requirements, nor by the effects of yes response. Consistently, the post-judgment cued-recall test exhibited a better retrieval performance for task-related associations than for the same type but task-unrelated associations. Results also showed that, the semantic relatedness between the to-be-associated individual words (e.g., the related word pair healthy-hospital versus the unrelated word pair price-way) was not enough to activate the hippocampus when it was task-unrelated. Generally, we proposed that, through participating in forming of task-related associations and consolidating of episodic memory, hippocampus enabled the organism to keep the information that owned great survival values in mind for future usage." @default.
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• W2063089076 date "2008-08-01" @default.
• W2063089076 modified "2023-09-23" @default.
• W2063089076 title "Hippocampus’s role in forming “task-related” associations: Flashing to the things you are looking for" @default.
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• W2063089076 doi "https://doi.org/10.1007/s11434-008-0321-6" @default.
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