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- W2063116392 abstract "Various kinds of water-soluble 9-acyloxyellipticine derivatives were synthesized in a search for compounds with potent antitumor activity. Antitumor activities against several tumors in mice (P388 leukemia, colon 26, Lewis lung carcinoma and B16 melanoma) were evaluated by using intravenous administration. Many compounds exhibited good antitumor activities; in particular, the glutarate derivative (5o) showed potent antitumor activity. This comopound (5o) may be converted to 9-hydroxyellipticine (2) by enzyme-catalyzed hydrolysis in the body." @default.
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- W2063116392 date "1997-01-01" @default.
- W2063116392 modified "2023-10-18" @default.
- W2063116392 title "Synthesis and Antitumor Activity of 9-Acyloxyellipticines." @default.
- W2063116392 doi "https://doi.org/10.1248/cpb.45.1156" @default.
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