FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063172021> ?p ?o ?g. }

• W2063172021 endingPage "1200" @default.
• W2063172021 startingPage "1192" @default.
• W2063172021 abstract "Patients with underlying renal disease may be vulnerable to vancomycin-mediated nephrotoxicity and Staphylococcus aureus bacteremia treatment failure. In light of recent data demonstrating the successful use of β-lactam plus daptomycin in very difficult cases of S. aureus bacteremia, we examined safety and clinical outcomes for patients who received daptomycin with or without concomitant β-lactams. We identified 106 patients who received daptomycin for S. aureus bacteremia, had mild or moderate renal insufficiency according to FDA criteria, and enrolled in the Cubicin Outcomes Registry and Experience (CORE), a multicenter registry, from 2005 to 2009. Daptomycin treatment success was 81%. Overall treatment efficacy was slightly enhanced with the addition of a β-lactam (87% versus 78%; P = 0.336), but this trend was most pronounced for bacteremia associated with endocarditis or bone/joint infection or bacteremia from an unknown source (90% versus 57%; P = 0.061). Factors associated with reduced daptomycin efficacy (by logistic regression) were an unknown source of bacteremia (odds ratio [OR] = 7.59; 95% confidence interval [CI] = 1.55 to 37.2), moderate renal impairment (OR = 9.11; 95% CI = 1.46 to 56.8), and prior vancomycin failure (OR = 11.2; 95% CI = 1.95 to 64.5). Two patients experienced an increase in creatine phosphokinase (CPK) that resolved after stopping daptomycin. No patients developed worsening renal insufficiency related to daptomycin. In conclusion, daptomycin appeared to be effective and well tolerated in patients with S. aureus bacteremia and mild to moderate renal insufficiency. Daptomycin treatment efficacy might be enhanced with β-lactam combination therapy in primary endovascular and bone/joint infections. Additional studies will be necessary to confirm these findings." @default.
• W2063172021 created "2016-06-24" @default.
• W2063172021 creator A5006503604 @default.
• W2063172021 creator A5010993325 @default.
• W2063172021 creator A5016366474 @default.
• W2063172021 creator A5017445754 @default.
• W2063172021 creator A5022639391 @default.
• W2063172021 creator A5023470932 @default.
• W2063172021 creator A5053081800 @default.
• W2063172021 creator A5064512017 @default.
• W2063172021 creator A5075853165 @default.
• W2063172021 date "2013-03-01" @default.
• W2063172021 modified "2023-09-26" @default.
• W2063172021 title "Multicenter Evaluation of the Clinical Outcomes of Daptomycin with and without Concomitant β-Lactams in Patients with Staphylococcus aureus Bacteremia and Mild to Moderate Renal Impairment" @default.
• W2063172021 cites W1884980943 @default.
• W2063172021 cites W1982348201 @default.
• W2063172021 cites W1998918836 @default.
• W2063172021 cites W2001914137 @default.
• W2063172021 cites W2002249283 @default.
• W2063172021 cites W2024370781 @default.
• W2063172021 cites W2044368480 @default.
• W2063172021 cites W2053081212 @default.
• W2063172021 cites W2073262651 @default.
• W2063172021 cites W2076342820 @default.
• W2063172021 cites W2087937367 @default.
• W2063172021 cites W2095215130 @default.
• W2063172021 cites W2098479591 @default.
• W2063172021 cites W2099481682 @default.
• W2063172021 cites W2108433768 @default.
• W2063172021 cites W2111070278 @default.
• W2063172021 cites W2111442039 @default.
• W2063172021 cites W2112549514 @default.
• W2063172021 cites W2114585210 @default.
• W2063172021 cites W2117913801 @default.
• W2063172021 cites W2119317021 @default.
• W2063172021 cites W2133120422 @default.
• W2063172021 cites W2133613588 @default.
• W2063172021 cites W2136296616 @default.
• W2063172021 cites W2138194474 @default.
• W2063172021 cites W2142848829 @default.
• W2063172021 cites W2143134882 @default.
• W2063172021 cites W2143185955 @default.
• W2063172021 cites W2144504167 @default.
• W2063172021 cites W2145830075 @default.
• W2063172021 cites W2146598854 @default.
• W2063172021 cites W2151746991 @default.
• W2063172021 cites W2161881689 @default.
• W2063172021 cites W2162000793 @default.
• W2063172021 cites W2168482920 @default.
• W2063172021 cites W2168625432 @default.
• W2063172021 cites W2171436655 @default.
• W2063172021 cites W2323611005 @default.
• W2063172021 doi "https://doi.org/10.1128/aac.02192-12" @default.
• W2063172021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3591880" @default.
• W2063172021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23254428" @default.
• W2063172021 hasPublicationYear "2013" @default.
• W2063172021 type Work @default.
• W2063172021 sameAs 2063172021 @default.
• W2063172021 citedByCount "75" @default.
• W2063172021 countsByYear W20631720212013 @default.
• W2063172021 countsByYear W20631720212014 @default.
• W2063172021 countsByYear W20631720212015 @default.
• W2063172021 countsByYear W20631720212016 @default.
• W2063172021 countsByYear W20631720212017 @default.
• W2063172021 countsByYear W20631720212018 @default.
• W2063172021 countsByYear W20631720212019 @default.
• W2063172021 countsByYear W20631720212020 @default.
• W2063172021 countsByYear W20631720212021 @default.
• W2063172021 countsByYear W20631720212022 @default.
• W2063172021 crossrefType "journal-article" @default.
• W2063172021 hasAuthorship W2063172021A5006503604 @default.
• W2063172021 hasAuthorship W2063172021A5010993325 @default.
• W2063172021 hasAuthorship W2063172021A5016366474 @default.
• W2063172021 hasAuthorship W2063172021A5017445754 @default.
• W2063172021 hasAuthorship W2063172021A5022639391 @default.
• W2063172021 hasAuthorship W2063172021A5023470932 @default.
• W2063172021 hasAuthorship W2063172021A5053081800 @default.
• W2063172021 hasAuthorship W2063172021A5064512017 @default.
• W2063172021 hasAuthorship W2063172021A5075853165 @default.
• W2063172021 hasBestOaLocation W20631720211 @default.
• W2063172021 hasConcept C126322002 @default.
• W2063172021 hasConcept C141071460 @default.
• W2063172021 hasConcept C156957248 @default.
• W2063172021 hasConcept C2775872228 @default.
• W2063172021 hasConcept C2778651397 @default.
• W2063172021 hasConcept C2778653478 @default.
• W2063172021 hasConcept C2778980435 @default.
• W2063172021 hasConcept C2779384505 @default.
• W2063172021 hasConcept C2779443120 @default.
• W2063172021 hasConcept C2779489039 @default.
• W2063172021 hasConcept C501593827 @default.
• W2063172021 hasConcept C523546767 @default.
• W2063172021 hasConcept C54355233 @default.
• W2063172021 hasConcept C71924100 @default.
• W2063172021 hasConcept C86803240 @default.
• W2063172021 hasConcept C89423630 @default.
• W2063172021 hasConceptScore W2063172021C126322002 @default.
• W2063172021 hasConceptScore W2063172021C141071460 @default.

• next