FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063183886> ?p ?o ?g. }

• W2063183886 endingPage "39" @default.
• W2063183886 startingPage "32" @default.
• W2063183886 abstract "Summary: Proton magnetic resonance spectroscopy (MRS) studies have shown focal reductions of N ‐acetyl aspartate (NAA) signal in patients with different forms of temporal lobe epilepsy (TLE), including those with normal magnetic resonance imaging (MRI), as well as extratemporal partial epilepsies. Both single‐voxel and multivoxel 1 H‐MRS have high sensitivity for detecting low NAA, indicative of neuronal dysfunction in focal epilepsies. Decreases in NAA correlate strongly with EEG abnormalities and severity of cell loss, and may be a more sensitive measure than structural MRI. However, the NAA decrease is often more widespread than the epileptogenic focus. The results of published MRS studies suggest that in patients with partial epilepsy, there is a metabolic abnormality throughout the brain, with patterns of asymmetry and focal accentuation that are useful for noninvasive localization of epileptogenic foci. A major limitation of current proton MRS studies in epilepsy is the inability to cover the entire brain in a single acquisition, thus leading to major sampling bias. The area of maximal abnormality may reside farther away, even when there is an abnormality inside of the volume of interest used for that particular examination. Decreased NAA ratios are present even in children at the onset of their epilepsy, and evidence points to a gradual and progressive course of further reduction in NAA values. Conversely, the relative NAA concentration can recover ipsilaterally and contralaterally after successful resection of a temporal lobe focus. These observations, together with the fact of the often widespread NAA abnormality, must be taken into account for the correct and adequate interpretation of proton MRS studies in the assessment of partial epilepsies." @default.
• W2063183886 created "2016-06-24" @default.
• W2063183886 creator A5006679597 @default.
• W2063183886 creator A5008598861 @default.
• W2063183886 creator A5034100976 @default.
• W2063183886 creator A5038960596 @default.
• W2063183886 creator A5044809264 @default.
• W2063183886 creator A5075572802 @default.
• W2063183886 creator A5083003643 @default.
• W2063183886 creator A5083212886 @default.
• W2063183886 date "2002-01-01" @default.
• W2063183886 modified "2023-10-02" @default.
• W2063183886 title "Magnetic Resonance Spectroscopy in Epilepsy: Clinical Issues" @default.
• W2063183886 cites W1963967604 @default.
• W2063183886 cites W1970959659 @default.
• W2063183886 cites W1981014506 @default.
• W2063183886 cites W1981924762 @default.
• W2063183886 cites W1984066695 @default.
• W2063183886 cites W1984067525 @default.
• W2063183886 cites W1990495050 @default.
• W2063183886 cites W1997920681 @default.
• W2063183886 cites W1999578225 @default.
• W2063183886 cites W2002871377 @default.
• W2063183886 cites W2004056002 @default.
• W2063183886 cites W2006283660 @default.
• W2063183886 cites W2006355389 @default.
• W2063183886 cites W2009101311 @default.
• W2063183886 cites W2012023014 @default.
• W2063183886 cites W2013256573 @default.
• W2063183886 cites W2015473428 @default.
• W2063183886 cites W2016984701 @default.
• W2063183886 cites W2018256104 @default.
• W2063183886 cites W2023272399 @default.
• W2063183886 cites W2023901164 @default.
• W2063183886 cites W2024786756 @default.
• W2063183886 cites W2028756615 @default.
• W2063183886 cites W2030182697 @default.
• W2063183886 cites W2032246984 @default.
• W2063183886 cites W2040351640 @default.
• W2063183886 cites W2042712208 @default.
• W2063183886 cites W2046603905 @default.
• W2063183886 cites W2055097674 @default.
• W2063183886 cites W2061496400 @default.
• W2063183886 cites W2063431778 @default.
• W2063183886 cites W2064243125 @default.
• W2063183886 cites W2066365005 @default.
• W2063183886 cites W2067330382 @default.
• W2063183886 cites W2069265040 @default.
• W2063183886 cites W2069405063 @default.
• W2063183886 cites W2070506499 @default.
• W2063183886 cites W2072066577 @default.
• W2063183886 cites W2077704161 @default.
• W2063183886 cites W2078134381 @default.
• W2063183886 cites W2078689130 @default.
• W2063183886 cites W2078962795 @default.
• W2063183886 cites W2079159386 @default.
• W2063183886 cites W2079431350 @default.
• W2063183886 cites W2081023192 @default.
• W2063183886 cites W2083082730 @default.
• W2063183886 cites W2088388877 @default.
• W2063183886 cites W2091423543 @default.
• W2063183886 cites W2094131569 @default.
• W2063183886 cites W2095583754 @default.
• W2063183886 cites W2101660242 @default.
• W2063183886 cites W2102106700 @default.
• W2063183886 cites W2103376251 @default.
• W2063183886 cites W2105712524 @default.
• W2063183886 cites W2111543822 @default.
• W2063183886 cites W2111753311 @default.
• W2063183886 cites W2118129131 @default.
• W2063183886 cites W2119825727 @default.
• W2063183886 cites W2127854791 @default.
• W2063183886 cites W2133006254 @default.
• W2063183886 cites W2133995671 @default.
• W2063183886 cites W2157590017 @default.
• W2063183886 cites W2160760539 @default.
• W2063183886 cites W2161351145 @default.
• W2063183886 cites W2164255848 @default.
• W2063183886 cites W2168846506 @default.
• W2063183886 doi "https://doi.org/10.1046/j.1528-1157.2002.043s1032.x" @default.
• W2063183886 hasPublicationYear "2002" @default.
• W2063183886 type Work @default.
• W2063183886 sameAs 2063183886 @default.
• W2063183886 citedByCount "28" @default.
• W2063183886 countsByYear W20631838862013 @default.
• W2063183886 countsByYear W20631838862014 @default.
• W2063183886 countsByYear W20631838862016 @default.
• W2063183886 countsByYear W20631838862019 @default.
• W2063183886 countsByYear W20631838862020 @default.
• W2063183886 countsByYear W20631838862021 @default.
• W2063183886 countsByYear W20631838862022 @default.
• W2063183886 crossrefType "journal-article" @default.
• W2063183886 hasAuthorship W2063183886A5006679597 @default.
• W2063183886 hasAuthorship W2063183886A5008598861 @default.
• W2063183886 hasAuthorship W2063183886A5034100976 @default.
• W2063183886 hasAuthorship W2063183886A5038960596 @default.
• W2063183886 hasAuthorship W2063183886A5044809264 @default.
• W2063183886 hasAuthorship W2063183886A5075572802 @default.

• next