FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063210577> ?p ?o ?g. }

• W2063210577 endingPage "358" @default.
• W2063210577 startingPage "350" @default.
• W2063210577 abstract "Context: It is necessary to advance the field of alternative treatments for chronic wounds that are financially accessible to the least economically developed countries. Previously we demonstrated that topical applications of Lactobacillus plantarum culture supernatants (LAPS) on human-infected chronic wounds reduce the pathogenic bioburden, the amount of necrotic tissue, and the wound area, as well as promote debridement, granulation tissue, and wound healing.Objective: To study LAPS chemically and biologically and to find potential molecules responsible for its pro-healing and anti-pathogenic properties in chronic wounds.Materials and methods: (1) Chemical analysis: extracts were subjected to a column chromatography and the fractions obtained were studied by GCMS. (2) Quantification: dl-lactic acid (commercial kit), phenolic compounds (Folin–Ciocalteu), H2O2 (micro-titration), and cations (flame photometry). (3) Biological analysis: autoinducers type 2 (AI-2) (Vibrio harveyi BB170 bioassay), DNAase activity (Agar DNAase), and Pseudomonas aeruginosa biofilm inhibition (crystal violet technique).Results: According to its biological activity, the most significant molecules found by GCMS were the following: antimicrobials (mevalonolactone, 5-methyl-hydantoine, benzoic acid, etc.); surfactants (di-palmitin, distearin, and 1,5-monolinolein); anesthetics (barbituric acid derivatives), and AI-2 precursors (4,5-dihydroxy-2,3-pentanedione and 2-methyl-2,3,3,4-tetrahydroxytetrahydrofurane). Concentrations measured (µg/mL): dl-lactic acid (11.71 ± 1.53) and H2O2 (36 ± 2.0); phenolic compounds (485.2 ± 15.20); sodium (370 ± 17); potassium 920 ± 24); calcium (20 ± 4); and magnesium (15 ± 3). DNAase from LAPS had activity on genomic DNA from PMNs and P. aeruginosa.Discussion and conclusion: The molecules and biological activities found in LAPS could explain the observed effects in human chronic wounds." @default.
• W2063210577 created "2016-06-24" @default.
• W2063210577 creator A5019210119 @default.
• W2063210577 creator A5033080866 @default.
• W2063210577 creator A5033327871 @default.
• W2063210577 creator A5045553607 @default.
• W2063210577 creator A5081435911 @default.
• W2063210577 creator A5086899633 @default.
• W2063210577 date "2014-10-27" @default.
• W2063210577 modified "2023-10-18" @default.
• W2063210577 title "Compounds from<i>Lactobacillus plantarum</i>culture supernatants with potential pro-healing and anti-pathogenic properties in skin chronic wounds" @default.
• W2063210577 cites W1540602097 @default.
• W2063210577 cites W1818684172 @default.
• W2063210577 cites W1851197753 @default.
• W2063210577 cites W1963626859 @default.
• W2063210577 cites W1964553975 @default.
• W2063210577 cites W1984846855 @default.
• W2063210577 cites W1986041162 @default.
• W2063210577 cites W1986308133 @default.
• W2063210577 cites W1987054304 @default.
• W2063210577 cites W1989324168 @default.
• W2063210577 cites W1991045187 @default.
• W2063210577 cites W1994462493 @default.
• W2063210577 cites W1996135784 @default.
• W2063210577 cites W1996778256 @default.
• W2063210577 cites W1996872292 @default.
• W2063210577 cites W2013385303 @default.
• W2063210577 cites W2015718294 @default.
• W2063210577 cites W2019548778 @default.
• W2063210577 cites W2026548787 @default.
• W2063210577 cites W2030160629 @default.
• W2063210577 cites W2034993279 @default.
• W2063210577 cites W2042669775 @default.
• W2063210577 cites W2043346930 @default.
• W2063210577 cites W2050078027 @default.
• W2063210577 cites W2056064788 @default.
• W2063210577 cites W2056368477 @default.
• W2063210577 cites W2064365613 @default.
• W2063210577 cites W2067477145 @default.
• W2063210577 cites W2094149145 @default.
• W2063210577 cites W2098064749 @default.
• W2063210577 cites W2098159838 @default.
• W2063210577 cites W2114106834 @default.
• W2063210577 cites W2121607410 @default.
• W2063210577 cites W2134515577 @default.
• W2063210577 cites W2138776000 @default.
• W2063210577 cites W2143554109 @default.
• W2063210577 cites W2144640625 @default.
• W2063210577 cites W2145402561 @default.
• W2063210577 cites W2146292204 @default.
• W2063210577 cites W2150014711 @default.
• W2063210577 cites W2156382695 @default.
• W2063210577 cites W2159019565 @default.
• W2063210577 cites W2163542601 @default.
• W2063210577 cites W2166229810 @default.
• W2063210577 cites W2166832761 @default.
• W2063210577 cites W2167307872 @default.
• W2063210577 cites W2315482024 @default.
• W2063210577 doi "https://doi.org/10.3109/13880209.2014.920037" @default.
• W2063210577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25347359" @default.
• W2063210577 hasPublicationYear "2014" @default.
• W2063210577 type Work @default.
• W2063210577 sameAs 2063210577 @default.
• W2063210577 citedByCount "32" @default.
• W2063210577 countsByYear W20632105772015 @default.
• W2063210577 countsByYear W20632105772016 @default.
• W2063210577 countsByYear W20632105772018 @default.
• W2063210577 countsByYear W20632105772019 @default.
• W2063210577 countsByYear W20632105772020 @default.
• W2063210577 countsByYear W20632105772021 @default.
• W2063210577 countsByYear W20632105772022 @default.
• W2063210577 countsByYear W20632105772023 @default.
• W2063210577 crossrefType "journal-article" @default.
• W2063210577 hasAuthorship W2063210577A5019210119 @default.
• W2063210577 hasAuthorship W2063210577A5033080866 @default.
• W2063210577 hasAuthorship W2063210577A5033327871 @default.
• W2063210577 hasAuthorship W2063210577A5045553607 @default.
• W2063210577 hasAuthorship W2063210577A5081435911 @default.
• W2063210577 hasAuthorship W2063210577A5086899633 @default.
• W2063210577 hasBestOaLocation W20632105771 @default.
• W2063210577 hasConcept C151730666 @default.
• W2063210577 hasConcept C185592680 @default.
• W2063210577 hasConcept C203014093 @default.
• W2063210577 hasConcept C2775920511 @default.
• W2063210577 hasConcept C2778660310 @default.
• W2063210577 hasConcept C2778985185 @default.
• W2063210577 hasConcept C2779343474 @default.
• W2063210577 hasConcept C2780104969 @default.
• W2063210577 hasConcept C2780269544 @default.
• W2063210577 hasConcept C31903555 @default.
• W2063210577 hasConcept C523546767 @default.
• W2063210577 hasConcept C54355233 @default.
• W2063210577 hasConcept C86803240 @default.
• W2063210577 hasConcept C89423630 @default.
• W2063210577 hasConceptScore W2063210577C151730666 @default.
• W2063210577 hasConceptScore W2063210577C185592680 @default.
• W2063210577 hasConceptScore W2063210577C203014093 @default.
• W2063210577 hasConceptScore W2063210577C2775920511 @default.

• next