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- W2063212198 abstract "Mutant ms (1)6S of Drosophila melanogaster is characterized by a spectrum of abnormalities of spermatid differentiation. Included in these are failure of the basal body to make normal attachment to the nucleus, failure of acrosomes to develop, and lack of a normal population of perinuclear microtubules. There is also a failure of normal chromatin condensation and nuclear elongation. The mitochondria do not form a normal nebenkern, but nevertheless fuse, elongate, and develop paracrystalline bodies. The number of normal axonemes is markedly reduced as a result of the failure of some centrioles to form basal bodies. All of these aberrations can be related to defective interactions of the “centrosome” or “microtubule-organizing-centre” with other organelles. The analysis of spermiogenesis in this mutant further clarifies the roles of microtubules in nuclear condensation and elongation and in cellular elongation in general." @default.
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- W2063212198 date "1977-08-01" @default.
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- W2063212198 title "Genetic control of spermiogenesis in Drosophila melanogaster: The effects of abnormal association of centrosome and nucleus in mutant ms(1)6S" @default.
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- W2063212198 doi "https://doi.org/10.1016/s0022-5320(77)80067-1" @default.
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