Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063249570> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2063249570 abstract "The recent development of an ultrasensitive immunofluorometric rat LH assay makes possible evaluation of pulsatile LH secretion in intact male rats under physiological conditions of minimal volume blood sampling without requiring orchidectomy. Specifically, we applied this assay to determine the effect of macronutrient restriction on pulsatile LH secretion in the presence or absence of testes. In testes-intact rats, halving of food intake for 7 days while maintaining micronutrient supply caused a reduction of mean, maximal, and basal LH levels and LH pulse amplitude (all P < 0.05) compared with those in ad libitum fed controls. The loss of body weight was positively correlated with decreases in mean LH level, pulse amplitude, and area under the curve (all P < 0.009). In contrast, the same food restriction in castrated rats caused an increase in pulse length and area under the curve and a decrease in pulse frequency, but did not change mean, maximal, and basal LH levels or LH pulse amplitude compared to castrated ad libitum fed controls (all P < 0.02). The observed positive correlations between body weight and the LH secretion parameters in intact rats were absent or reversed in castrated rats. This study demonstrates qualitatively different effects of macronutrient restriction on pulsatile LH secretion in castrated and intact rats, indicating that it is not necessary valid to extrapolate consequences of undernutrition on LH secretion from castrate to intact male rats. We conclude that undernutrition-induced inhibition of LH secretion involves both an indirect suppression of LH secretion via amplification of endogenous testicular negative feedback as well as more direct suppression of GnRH release." @default.
- W2063249570 created "2016-06-24" @default.
- W2063249570 creator A5014846710 @default.
- W2063249570 creator A5033717242 @default.
- W2063249570 creator A5051955190 @default.
- W2063249570 creator A5088392007 @default.
- W2063249570 date "1994-08-01" @default.
- W2063249570 modified "2023-09-24" @default.
- W2063249570 title "Effect of undernutrition on pulsatile luteinizing hormone (LH) secretion in castrate and intact male rats using an ultrasensitive immunofluorometric LH assay." @default.
- W2063249570 cites W1558956026 @default.
- W2063249570 cites W1936724401 @default.
- W2063249570 cites W1976536522 @default.
- W2063249570 cites W1978308275 @default.
- W2063249570 cites W1979556744 @default.
- W2063249570 cites W1983542426 @default.
- W2063249570 cites W1986118516 @default.
- W2063249570 cites W1989301672 @default.
- W2063249570 cites W1997768813 @default.
- W2063249570 cites W1999831221 @default.
- W2063249570 cites W2001542573 @default.
- W2063249570 cites W2003814064 @default.
- W2063249570 cites W2013927954 @default.
- W2063249570 cites W2020562485 @default.
- W2063249570 cites W2021080540 @default.
- W2063249570 cites W2024081693 @default.
- W2063249570 cites W2038753834 @default.
- W2063249570 cites W2058697479 @default.
- W2063249570 cites W2058746698 @default.
- W2063249570 cites W2070193527 @default.
- W2063249570 cites W2071599591 @default.
- W2063249570 cites W2076272004 @default.
- W2063249570 cites W2079273383 @default.
- W2063249570 cites W2079918392 @default.
- W2063249570 cites W2088991685 @default.
- W2063249570 cites W2092206211 @default.
- W2063249570 cites W2121299924 @default.
- W2063249570 cites W2146900772 @default.
- W2063249570 doi "https://doi.org/10.1210/endo.135.2.8033822" @default.
- W2063249570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8033822" @default.
- W2063249570 hasPublicationYear "1994" @default.
- W2063249570 type Work @default.
- W2063249570 sameAs 2063249570 @default.
- W2063249570 citedByCount "22" @default.
- W2063249570 countsByYear W20632495702013 @default.
- W2063249570 countsByYear W20632495702016 @default.
- W2063249570 countsByYear W20632495702018 @default.
- W2063249570 countsByYear W20632495702019 @default.
- W2063249570 countsByYear W20632495702021 @default.
- W2063249570 crossrefType "journal-article" @default.
- W2063249570 hasAuthorship W2063249570A5014846710 @default.
- W2063249570 hasAuthorship W2063249570A5033717242 @default.
- W2063249570 hasAuthorship W2063249570A5051955190 @default.
- W2063249570 hasAuthorship W2063249570A5088392007 @default.
- W2063249570 hasConcept C126322002 @default.
- W2063249570 hasConcept C134018914 @default.
- W2063249570 hasConcept C185592680 @default.
- W2063249570 hasConcept C2778024521 @default.
- W2063249570 hasConcept C2778575703 @default.
- W2063249570 hasConcept C2779306644 @default.
- W2063249570 hasConcept C71315377 @default.
- W2063249570 hasConcept C71924100 @default.
- W2063249570 hasConcept C79191276 @default.
- W2063249570 hasConcept C86803240 @default.
- W2063249570 hasConceptScore W2063249570C126322002 @default.
- W2063249570 hasConceptScore W2063249570C134018914 @default.
- W2063249570 hasConceptScore W2063249570C185592680 @default.
- W2063249570 hasConceptScore W2063249570C2778024521 @default.
- W2063249570 hasConceptScore W2063249570C2778575703 @default.
- W2063249570 hasConceptScore W2063249570C2779306644 @default.
- W2063249570 hasConceptScore W2063249570C71315377 @default.
- W2063249570 hasConceptScore W2063249570C71924100 @default.
- W2063249570 hasConceptScore W2063249570C79191276 @default.
- W2063249570 hasConceptScore W2063249570C86803240 @default.
- W2063249570 hasLocation W20632495701 @default.
- W2063249570 hasLocation W20632495702 @default.
- W2063249570 hasOpenAccess W2063249570 @default.
- W2063249570 hasPrimaryLocation W20632495701 @default.
- W2063249570 hasRelatedWork W2032650231 @default.
- W2063249570 hasRelatedWork W2036239614 @default.
- W2063249570 hasRelatedWork W2041693873 @default.
- W2063249570 hasRelatedWork W2062564531 @default.
- W2063249570 hasRelatedWork W2063249570 @default.
- W2063249570 hasRelatedWork W2085735884 @default.
- W2063249570 hasRelatedWork W2098767853 @default.
- W2063249570 hasRelatedWork W2153510880 @default.
- W2063249570 hasRelatedWork W2324562794 @default.
- W2063249570 hasRelatedWork W3080261640 @default.
- W2063249570 isParatext "false" @default.
- W2063249570 isRetracted "false" @default.
- W2063249570 magId "2063249570" @default.
- W2063249570 workType "article" @default.