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• W2063278239 abstract "Stereotactic radiotherapy using a linear accelerator is usually equated with the technique of delivery using multiple non-coplanar arcs, which achieves a spherical dose distribution. As the majority of intracranial lesions are not spherical, a range of schematized tumour shapes were planned to assess the role of static conformal beams in the treatment of irregular lesions. A sphere and 2 ellipsoids, ranging from 20 to 50 mm maximum diameter located intracranially were planned using 3, 4, and 6 non-coplanar static beams with conformal blocks and were compared with four 120 non-coplanar arcs. Comparison of the plans was made by the relative sparing of normal tissue outside the target volume using three-dimensional dose-volume distributions. Non-coplanar arcs spared more normal tissue at low isodoses and achieved the best high dose sparing for spherical targets. For the majority of irregular targets, 3 and 4 static beams spared more tissue at doses ≥ 50% and ≥ 80% than the arc technique. For all irregular volumes, maximum sparing of normal tissue to isodoses ≥ 50% and ≥ 80% of the treatment isodose was obtained with 6 static conformal beams. We conclude that irregularly shaped tumours suitable for stereotactic radiotherapy with a linear accelerator are better treated with conformal static non-coplanar beams rather than with the multiple arc technique." @default.
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• W2063278239 date "1993-09-01" @default.
• W2063278239 modified "2023-10-18" @default.
• W2063278239 title "Stereotactic radiotherapy of irregular targets: a comparison between static conformal beams and non-coplanar arcs" @default.
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• W2063278239 doi "https://doi.org/10.1016/0167-8140(93)90064-f" @default.
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